SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bt6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 9 ASP A  64
ILE A  97
PRO A  96
ILE A 243
THR A  91
 None
 1.29A 1aj6A-3bt6A:
undetectable		 1aj6A-3bt6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		4 / 7 LEU A 286
LEU A  84
GLY A 282
LEU A 293
 None
 0.71A 1gtiA-3bt6A:
undetectable		 1gtiA-3bt6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 11 LEU B  58
ALA B  99
LEU A 326
LEU A  32
VAL B  60
 None
 1.14A 1ictA-3bt6B:
undetectable
1ictC-3bt6B:
undetectable		 1ictA-3bt6B:
25.15
1ictC-3bt6B:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 ASP A  64
ILE A  97
PRO A  96
ILE A 243
THR A  91
 None
 1.23A 1kijA-3bt6A:
undetectable		 1kijA-3bt6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 ASP A  64
ILE A  97
PRO A  96
ILE A 243
THR A  91
 None
 1.28A 1kijB-3bt6A:
undetectable		 1kijB-3bt6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 9 GLY A   6
GLY B  12
GLY B   4
GLY B   1
ASP B 112
 None
 0.94A 1mxdA-3bt6A:
undetectable		 1mxdA-3bt6A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 11 GLY A   6
GLY B  12
GLY B   4
GLY B   1
ASP B 112
 None
 0.93A 1mxgA-3bt6A:
undetectable		 1mxgA-3bt6A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 11 ARG A  50
LEU A 286
PHE A  41
ARG B  65
GLY A 282
 None
 1.26A 2bxmA-3bt6A:
undetectable		 2bxmA-3bt6A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		4 / 6 THR A  47
THR A  49
ILE A 315
LEU A 293
 None
 0.96A 3deuB-3bt6A:
undetectable		 3deuB-3bt6A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 THR B  25
GLY B  23
ILE B 152
LEU B 118
THR B 140
 None
 1.07A 3eeyC-3bt6B:
undetectable		 3eeyC-3bt6B:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 THR B  25
GLY B  23
ILE B 152
LEU B 118
THR B 140
 None
 1.05A 3eeyE-3bt6B:
undetectable		 3eeyE-3bt6B:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 THR B  25
GLY B  23
ILE B 152
LEU B 118
THR B 140
 None
 1.14A 3eeyF-3bt6B:
undetectable		 3eeyF-3bt6B:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		4 / 6 SER B  26
TYR B  24
ALA B  33
LEU B 122
 None
 1.07A 3ravA-3bt6B:
2.0		 3ravA-3bt6B:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 11 MET A 156
PHE A 152
GLY A 138
SER A 140
PHE A  95
 None
 1.44A 3v3nA-3bt6A:
undetectable		 3v3nA-3bt6A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 11 MET A 156
PHE A 152
GLY A 138
SER A 140
PHE A  95
 None
 1.44A 3v3nD-3bt6A:
undetectable		 3v3nD-3bt6A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		4 / 5 THR A  91
LEU A  67
THR A 186
MET A 248
 None
 1.38A 4mbsB-3bt6A:
undetectable		 4mbsB-3bt6A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus;
Influenza
B
virus) 		4 / 7 ASP B  71
GLN A 106
PRO A 108
ASP A 100
 None
 1.04A 4pcuA-3bt6B:
undetectable		 4pcuA-3bt6B:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 VAL A 279
GLY B  68
GLY A 275
ASP A 183
LYS A 251
 None
 1.41A 4pevB-3bt6A:
undetectable		 4pevB-3bt6A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 ASP A  64
ILE A  97
PRO A  96
ILE A 243
THR A  91
 None
 1.20A 4uroD-3bt6A:
undetectable		 4uroD-3bt6A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		4 / 5 SER B  40
GLY B 106
THR A  20
GLU B 105
 None
 1.15A 5btiA-3bt6B:
undetectable
5btiB-3bt6B:
undetectable		 5btiA-3bt6B:
15.34
5btiB-3bt6B:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		4 / 5 SER B  40
GLY B 106
THR A  20
GLU B 105
 None
 1.17A 5btiC-3bt6B:
undetectable
5btiD-3bt6B:
undetectable		 5btiC-3bt6B:
15.34
5btiD-3bt6B:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		3 / 3 ASP A  64
ASN A  59
PHE A  95
 None
 0.92A 5jglB-3bt6A:
undetectable		 5jglB-3bt6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		5 / 12 GLY B   8
LEU B 115
LEU B 118
GLU B 119
LEU B 116
 None
 1.24A 5nwwA-3bt6B:
undetectable		 5nwwA-3bt6B:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus;
Influenza
B
virus) 		5 / 10 LEU A 111
GLY A 113
GLY B  68
VAL A 249
ALA A 273
 None
 1.04A 5o96E-3bt6A:
undetectable
5o96F-3bt6A:
undetectable		 5o96E-3bt6A:
20.12
5o96F-3bt6A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3bt6 INFLUENZA B
HEMAGGLUTININ (HA)
(Influenza
B
virus) 		4 / 8 ILE B  48
THR B  49
GLU B  57
SER B  56
 None
 0.82A 6c06C-3bt6B:
undetectable		 6c06C-3bt6B:
undetectable