SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bu2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA506_0 (RNA POLYMERASE 3D-POL)	3bu2	PUTATIVE TRNA-BINDING PROTEIN (Staphylococcus saprophyticus)	3 / 3	VAL A 138 GLY A 96 LYS A 136	None	0.59A	4k50A-3bu2A: undetectable	4k50A-3bu2A: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE504_0 (RNA POLYMERASE 3D-POL)	3bu2	PUTATIVE TRNA-BINDING PROTEIN (Staphylococcus saprophyticus)	3 / 3	VAL A 138 GLY A 96 LYS A 136	None	0.66A	4k50E-3bu2A: undetectable	4k50E-3bu2A: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI504_0 (RNA POLYMERASE 3D-POL)	3bu2	PUTATIVE TRNA-BINDING PROTEIN (Staphylococcus saprophyticus)	3 / 3	VAL A 138 GLY A 96 LYS A 136	None	0.58A	4k50I-3bu2A: undetectable	4k50I-3bu2A: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4N_C_ACTC201_0 (NITROGEN REGULATORY PROTEIN P-II)	3bu2	PUTATIVE TRNA-BINDING PROTEIN (Staphylococcus saprophyticus)	4 / 5	VAL A 28 VAL A 33 GLY A 31 PHE A 81	None	0.88A	5d4nA-3bu2A: undetectable 5d4nC-3bu2A: undetectable	5d4nA-3bu2A: 19.81 5d4nC-3bu2A: 19.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4K50_A_ACTA506_0","RNA POLYMERASE 3D-POL","3bu2","PUTATIVE TRNA-BINDING PROTEIN","Staphylococcus saprophyticus",3,"VAL A 138;GLY A  96;LYS A 136","None","0.59A","4k50A-3bu2A:undetectable","4k50A-3bu2A:18.14"],["4K50_E_ACTE504_0","RNA POLYMERASE 3D-POL","3bu2","PUTATIVE TRNA-BINDING PROTEIN","Staphylococcus saprophyticus",3,"VAL A 138;GLY A  96;LYS A 136","None","0.66A","4k50E-3bu2A:undetectable","4k50E-3bu2A:18.14"],["4K50_I_ACTI504_0","RNA POLYMERASE 3D-POL","3bu2","PUTATIVE TRNA-BINDING PROTEIN","Staphylococcus saprophyticus",3,"VAL A 138;GLY A  96;LYS A 136","None","0.58A","4k50I-3bu2A:undetectable","4k50I-3bu2A:18.14"],["5D4N_C_ACTC201_0","NITROGEN REGULATORY PROTEIN P-II","3bu2","PUTATIVE TRNA-BINDING PROTEIN","Staphylococcus saprophyticus",4,"VAL A  28;VAL A  33;GLY A  31;PHE A  81","None","0.88A","5d4nA-3bu2A:undetectable;5d4nC-3bu2A:undetectable","5d4nA-3bu2A:19.81;5d4nC-3bu2A:19.81"]]