SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bu8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3bu8 TELOMERIC
REPEAT-BINDING
FACTOR 2
(Homo
sapiens) 		4 / 4 THR A  96
LEU A 100
VAL A 103
LEU A 107
 None
 0.78A 1fbmD-3bu8A:
undetectable		 1fbmD-3bu8A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 3bu8 TELOMERIC
REPEAT-BINDING
FACTOR 2
(Homo
sapiens) 		5 / 12 LEU A 145
VAL A 150
SER A 227
LEU A 136
LEU A 107
 None
 1.16A 1mx1E-3bu8A:
undetectable		 1mx1E-3bu8A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bu8 TELOMERIC
REPEAT-BINDING
FACTOR 2
(Homo
sapiens) 		3 / 3 GLU A 114
GLU A 170
LEU A 204
 None
 0.65A 1v8bA-3bu8A:
undetectable		 1v8bA-3bu8A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3bu8 TELOMERIC
REPEAT-BINDING
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  66
GLY A  74
ASP A  81
ILE A  82
ILE A  79
 None
 1.00A 2hs1A-3bu8A:
undetectable		 2hs1A-3bu8A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3bu8 TELOMERIC
REPEAT-BINDING
FACTOR 2
(Homo
sapiens) 		5 / 12 GLU A 112
TYR A  73
PHE A  68
ALA A  64
ASP A  81
 None
 1.27A 3nmuA-3bu8A:
undetectable
3nmuF-3bu8A:
undetectable		 3nmuA-3bu8A:
24.71
3nmuF-3bu8A:
21.30