SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		4 / 8 LEU A 257
ARG A 221
LEU A  28
SER A 223
 None
 1.12A 1hk3A-3busA:
undetectable		 1hk3A-3busA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
ILE A  92
ASP A 119
SER A 138
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
SAH  A 274 (-3.6A)
None
 0.48A 1ri4A-3busA:
17.2		 1ri4A-3busA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		6 / 12 GLY A  71
ILE A  92
SER A  93
ALA A 120
SER A 138
HIS A 141
 SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
None
SAH  A 274 (-3.5A)
None
SAH  A 274 (-4.0A)
 0.92A 1ve3A-3busA:
18.5		 1ve3A-3busA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		6 / 12 GLY A  71
ILE A  92
SER A  93
ALA A 120
SER A 138
HIS A 141
 SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
None
SAH  A 274 (-3.5A)
None
SAH  A 274 (-4.0A)
 0.81A 1ve3B-3busA:
19.1		 1ve3B-3busA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 11 LEU A 224
HIS A 141
HIS A 140
PHE A 184
GLY A  25
 None
SAH  A 274 (-4.0A)
None
None
None
 1.17A 1zz1A-3busA:
3.0		 1zz1A-3busA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 LEU A 224
HIS A 141
HIS A 140
PHE A 184
GLY A  25
 None
SAH  A 274 (-4.0A)
None
None
None
 1.19A 1zz1B-3busA:
3.5
1zz1C-3busA:
3.9		 1zz1B-3busA:
24.27
1zz1C-3busA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		4 / 6 LEU A 247
VAL A 238
MET A 250
ILE A 251
 None
 0.77A 2piwA-3busA:
undetectable		 2piwA-3busA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 HIS A  29
GLY A  69
GLY A  71
LEU A 136
ILE A  92
 SAH  A 274 (-4.2A)
SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.3A)
SAH  A 274 (-4.0A)
 1.15A 3cjtG-3busA:
15.1		 3cjtG-3busA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
ILE A  92
ALA A 120
LEU A 136
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
SAH  A 274 (-3.5A)
SAH  A 274 (-4.3A)
 0.91A 3ckkA-3busA:
11.1		 3ckkA-3busA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 VAL A  68
GLY A  69
GLY A  71
ASP A 119
ALA A 120
 None
SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-3.6A)
SAH  A 274 (-3.5A)
 0.67A 3fuuA-3busA:
12.3		 3fuuA-3busA:
27.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 11 GLY A  69
GLY A  71
ILE A  92
ASP A 119
ALA A 120
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
SAH  A 274 (-3.6A)
SAH  A 274 (-3.5A)
 0.69A 3grvA-3busA:
4.4		 3grvA-3busA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 7 GLY A 189
GLY A 188
LEU A  28
PHE A 167
HIS A 140
 None
 1.31A 3o9mA-3busA:
undetectable		 3o9mA-3busA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLU A 245
GLY A 246
PHE A 231
ILE A  23
GLY A 243
 None
 1.22A 3ps9A-3busA:
11.4		 3ps9A-3busA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 11 ILE A 164
ARG A 145
ILE A 196
VAL A 266
VAL A 168
 None
 1.29A 3rf4A-3busA:
undetectable
3rf4B-3busA:
undetectable		 3rf4A-3busA:
18.22
3rf4B-3busA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 11 ILE A 164
ARG A 145
ILE A 196
VAL A 266
VAL A 168
 None
 1.33A 3rf4B-3busA:
undetectable
3rf4C-3busA:
undetectable		 3rf4B-3busA:
18.22
3rf4C-3busA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		4 / 7 ASP A  35
GLY A  37
ALA A  38
ASP A  39
 None
 0.76A 3t3cA-3busA:
undetectable		 3t3cA-3busA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
ILE A  92
SER A 138
HIS A 141
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
None
SAH  A 274 (-4.0A)
 0.95A 4iv0A-3busA:
24.5		 4iv0A-3busA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		6 / 12 GLY A  69
GLY A  71
ILE A  92
ASP A 119
SER A 138
HIS A 141
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
SAH  A 274 (-3.6A)
None
SAH  A 274 (-4.0A)
 0.90A 4iv0B-3busA:
24.9		 4iv0B-3busA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		6 / 12 GLY A  69
GLY A  71
SER A  93
ASP A 119
ALA A 120
HIS A 141
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
None
SAH  A 274 (-3.6A)
SAH  A 274 (-3.5A)
SAH  A 274 (-4.0A)
 0.81A 4krhA-3busA:
25.2		 4krhA-3busA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
SER A  93
ALA A 120
HIS A 141
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
None
SAH  A 274 (-3.5A)
SAH  A 274 (-4.0A)
 0.73A 4krhB-3busA:
25.5		 4krhB-3busA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
ILE A  92
SER A 138
HIS A 141
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
None
SAH  A 274 (-4.0A)
 0.89A 4mwzA-3busA:
25.4		 4mwzA-3busA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
ILE A  92
SER A 138
HIS A 141
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
None
SAH  A 274 (-4.0A)
 0.91A 4mwzB-3busA:
24.5		 4mwzB-3busA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		6 / 12 GLY A  69
GLY A  71
ILE A  92
SER A  93
LEU A 136
HIS A 141
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.0A)
None
SAH  A 274 (-4.3A)
SAH  A 274 (-4.0A)
 0.85A 4qdjA-3busA:
16.1		 4qdjA-3busA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
GLY A  73
SER A  91
ALA A 120
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
None
SAH  A 274 (-3.0A)
SAH  A 274 (-3.5A)
 0.85A 4uciA-3busA:
7.3		 4uciA-3busA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
GLY A  73
SER A  91
ALA A 120
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
None
SAH  A 274 (-3.0A)
SAH  A 274 (-3.5A)
 0.85A 4uciB-3busA:
7.3		 4uciB-3busA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
GLY A  73
SER A  91
ALA A 120
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
None
SAH  A 274 (-3.0A)
SAH  A 274 (-3.5A)
 0.86A 4uckA-3busA:
5.8		 4uckA-3busA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
PRO A  75
LEU A 136
GLU A 137
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
SAH  A 274 (-4.3A)
SAH  A 274 (-4.3A)
None
 1.31A 4x61A-3busA:
8.5		 4x61A-3busA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 THR A 227
ALA A 228
LEU A 247
ARG A 235
LEU A  28
 None
 1.13A 5gs4A-3busA:
undetectable		 5gs4A-3busA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  71
SER A  93
ASP A 119
SER A 138
HIS A 141
 SAH  A 274 (-3.4A)
None
SAH  A 274 (-3.6A)
None
SAH  A 274 (-4.0A)
 1.17A 5hikA-3busA:
17.8		 5hikA-3busA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 12 GLY A  69
GLY A  71
SER A  93
GLN A  96
ASP A 119
 SAH  A 274 (-3.1A)
SAH  A 274 (-3.4A)
None
SAH  A 274 (-2.8A)
SAH  A 274 (-3.6A)
 0.84A 5kpcB-3busA:
22.9		 5kpcB-3busA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		3 / 3 GLU A 200
TYR A 199
ARG A 145
 None
 0.76A 5uunA-3busA:
undetectable		 5uunA-3busA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		3 / 3 GLU A 200
TYR A 199
ARG A 145
 None
 0.71A 5uunB-3busA:
undetectable		 5uunB-3busA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 11 VAL A  68
GLY A  69
ASP A 119
ALA A 120
SER A 138
 None
SAH  A 274 (-3.1A)
SAH  A 274 (-3.6A)
SAH  A 274 (-3.5A)
None
 0.87A 5x6yA-3busA:
5.9		 5x6yA-3busA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 10 VAL A  68
GLY A  69
ASP A 119
ALA A 120
SER A 138
 None
SAH  A 274 (-3.1A)
SAH  A 274 (-3.6A)
SAH  A 274 (-3.5A)
None
 0.83A 5x6yB-3busA:
2.3		 5x6yB-3busA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 3bus METHYLTRANSFERASE
(Lechevalieria
aerocolonigenes) 		5 / 11 VAL A  68
GLY A  69
ASP A 119
ALA A 120
SER A 138
 None
SAH  A 274 (-3.1A)
SAH  A 274 (-3.6A)
SAH  A 274 (-3.5A)
None
 0.76A 5x6yC-3busA:
5.9		 5x6yC-3busA:
17.08