SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3but'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CAS_A_ASDA332_1 (3-OXO-5-BETA-STEROID 4-DEHYDROGENASE)	3but	UNCHARACTERIZED PROTEIN AF_0446 (Archaeoglobus fulgidus)	5 / 10	ASN A 44 TRP A 81 VAL A 46 VAL A 48 LEU A 78	None	1.32A	3casA-3butA: undetectable	3casA-3butA: 17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXV_D_MTXD2000_2 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	3but	UNCHARACTERIZED PROTEIN AF_0446 (Archaeoglobus fulgidus)	3 / 3	LEU A 73 ARG A 116 ASN A 44	None	0.76A	3qxvD-3butA: undetectable	3qxvD-3butA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJC_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	3but	UNCHARACTERIZED PROTEIN AF_0446 (Archaeoglobus fulgidus)	4 / 7	LEU A 124 ILE A 94 THR A 92 MET A 43	None	1.41A	5ljcA-3butA: undetectable	5ljcA-3butA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA608_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	3but	UNCHARACTERIZED PROTEIN AF_0446 (Archaeoglobus fulgidus)	3 / 3	GLY A 36 THR A 101 GLU A 103	None	0.59A	6b58A-3butA: undetectable	6b58A-3butA: 12.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CAS_A_ASDA332_1","3-OXO-5-BETA-STEROID 4-DEHYDROGENASE","3but","UNCHARACTERIZED PROTEIN AF_0446","Archaeoglobus fulgidus",5,"ASN A  44;TRP A  81;VAL A  46;VAL A  48;LEU A  78","None","1.32A","3casA-3butA:undetectable","3casA-3butA:17.74"],["3QXV_D_MTXD2000_2","ANTI-METHOTREXATE CDR1-4 GRAFT VHH","3but","UNCHARACTERIZED PROTEIN AF_0446","Archaeoglobus fulgidus",3,"LEU A  73;ARG A 116;ASN A  44","None","0.76A","3qxvD-3butA:undetectable","3qxvD-3butA:21.85"],["5LJC_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","3but","UNCHARACTERIZED PROTEIN AF_0446","Archaeoglobus fulgidus",4,"LEU A 124;ILE A  94;THR A  92;MET A  43","None","1.41A","5ljcA-3butA:undetectable","5ljcA-3butA:18.75"],["6B58_A_ACTA608_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","3but","UNCHARACTERIZED PROTEIN AF_0446","Archaeoglobus fulgidus",3,"GLY A  36;THR A 101;GLU A 103","None","0.59A","6b58A-3butA:undetectable","6b58A-3butA:12.48"]]