SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.51A 1fbmB-3bv4A:
undetectable		 1fbmB-3bv4A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.68A 1fbmD-3bv4A:
undetectable		 1fbmD-3bv4A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 5 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.55A 1fbmE-3bv4A:
undetectable		 1fbmE-3bv4A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 8 LEU A 283
PRO A 294
VAL A 267
GLY A 266
TRP A 295
 None
 1.48A 1hrkA-3bv4A:
undetectable		 1hrkA-3bv4A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 8 LEU A 283
PRO A 294
VAL A 267
GLY A 266
TRP A 295
 None
 1.47A 1hrkB-3bv4A:
undetectable		 1hrkB-3bv4A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 11 GLU A 187
LEU A 270
ILE A 185
TYR A 213
THR A 205
 None
13P  A3371 (-3.8A)
None
None
None
 1.18A 1jomA-3bv4A:
undetectable		 1jomA-3bv4A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		3 / 3 ALA A  19
HIS A  20
VAL A  23
 None
 0.49A 1lqtB-3bv4A:
undetectable		 1lqtB-3bv4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		3 / 3 ALA A  19
HIS A  20
VAL A  23
 None
 0.52A 1lquB-3bv4A:
undetectable		 1lquB-3bv4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.70A 1mz9D-3bv4A:
undetectable		 1mz9D-3bv4A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 10 LEU A 209
VAL A 264
VAL A 186
PRO A 294
LEU A 256
 None
 1.30A 1sv5A-3bv4A:
undetectable		 1sv5A-3bv4A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 5 TRP A 295
PRO A 261
LEU A 223
GLY A 225
 None
 1.30A 1ya4C-3bv4A:
undetectable		 1ya4C-3bv4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		3 / 3 PHE A 144
SER A 300
LEU A  30
 None
 0.71A 2w1bA-3bv4A:
undetectable		 2w1bA-3bv4A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 12 THR A 298
GLY A  28
ALA A  24
ALA A  31
ASP A  33
 None
None
None
13P  A3371 ( 4.3A)
None
 1.11A 2yvlD-3bv4A:
undetectable		 2yvlD-3bv4A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 9 GLY A 105
VAL A 104
ASP A 143
ILE A 182
VAL A 108
 None
 1.24A 3fi0O-3bv4A:
undetectable		 3fi0O-3bv4A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 12 GLY A 225
GLN A 178
VAL A 183
LEU A 216
ILE A  22
 None
 1.28A 3h52B-3bv4A:
undetectable		 3h52B-3bv4A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 12 GLY A 273
LEU A 270
GLU A 276
ALA A 279
ASN A 282
 None
13P  A3371 (-3.8A)
None
None
None
 1.07A 3kkzA-3bv4A:
undetectable		 3kkzA-3bv4A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		3 / 3 GLU A 187
LEU A 270
LEU A  30
 None
13P  A3371 (-3.8A)
None
 0.77A 3ohtB-3bv4A:
undetectable		 3ohtB-3bv4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		5 / 12 GLU A 187
LEU A 270
ILE A 185
TYR A 213
THR A 205
 None
13P  A3371 (-3.8A)
None
None
None
 1.14A 4ej1B-3bv4A:
undetectable		 4ej1B-3bv4A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 7 THR A 259
LEU A 151
ASN A 231
LEU A 270
 None
None
None
13P  A3371 (-3.8A)
 1.08A 4ib4A-3bv4A:
undetectable		 4ib4A-3bv4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 8 THR A 234
PRO A 235
SER A 244
HIS A 245
 None
 0.89A 4qknA-3bv4A:
undetectable		 4qknA-3bv4A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 8 ASN A 231
PRO A 230
PHE A 269
SER A 271
 None
None
None
13P  A3371 (-3.1A)
 1.42A 5amiB-3bv4A:
undetectable		 5amiB-3bv4A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 6 GLY A 273
ASP A  33
ILE A  39
ARG A  42
 None
None
None
SO4  A   1 (-3.2A)
 1.03A 5iwuA-3bv4A:
undetectable		 5iwuA-3bv4A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A
(Oryctolagus
cuniculus) 		4 / 5 ILE A  39
SER A  38
ALA A  31
LEU A  62
 None
None
13P  A3371 ( 4.3A)
None
 0.99A 6dwnA-3bv4A:
undetectable		 6dwnA-3bv4A:
12.21