SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3bv8 TETRAHYDRODIPICOLINA
TE ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 PRO A  37
TYR A  36
THR A  35
ILE A  34
 None
 0.84A 5mzrE-3bv8A:
undetectable		 5mzrE-3bv8A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3bv8 TETRAHYDRODIPICOLINA
TE ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 ILE A  51
PHE A  69
GLY A  29
PHE A  31
GLY A  44
 None
 1.34A 6awoA-3bv8A:
undetectable		 6awoA-3bv8A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3bv8 TETRAHYDRODIPICOLINA
TE ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 ILE A  51
PHE A  69
GLY A  29
PHE A  31
GLY A  44
 None
 1.34A 6awqA-3bv8A:
undetectable		 6awqA-3bv8A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3bv8 TETRAHYDRODIPICOLINA
TE ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 ILE A  51
PRO A  37
ILE A  23
THR A  21
 None
None
None
NA  A 101 ( 4.3A)
 1.02A 6cduG-3bv8A:
undetectable
6cduH-3bv8A:
undetectable		 6cduG-3bv8A:
13.29
6cduH-3bv8A:
13.29