SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 11 ILE A  38
ALA A  37
MET A  31
VAL A 132
LEU A 105
 None
 1.07A 1n4hA-3bvcA:
undetectable		 1n4hA-3bvcA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		4 / 8 VAL A 175
GLY A 176
THR A 130
ILE A 199
 None
 0.56A 2a1mB-3bvcA:
undetectable		 2a1mB-3bvcA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 12 LEU A 105
LEU A  80
ILE A  38
SER A  79
VAL A 132
 None
 1.13A 2hrcA-3bvcA:
undetectable		 2hrcA-3bvcA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 12 LEU A 105
LEU A  80
ILE A  38
SER A  79
VAL A 132
 None
 1.22A 2pnjB-3bvcA:
undetectable		 2pnjB-3bvcA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 12 LEU A 105
LEU A  80
ILE A  38
SER A  79
VAL A 132
 None
 1.22A 2po5A-3bvcA:
undetectable		 2po5A-3bvcA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 12 LEU A 105
LEU A  80
ILE A  38
SER A  79
VAL A 132
 None
 1.24A 3aqiB-3bvcA:
undetectable		 3aqiB-3bvcA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 12 LEU A 105
LEU A  80
ILE A  38
SER A  79
VAL A 132
 None
 1.27A 3w1wA-3bvcA:
undetectable		 3w1wA-3bvcA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		4 / 8 LEU A 179
LEU A 141
VAL A 171
ILE A 169
 None
 0.86A 4oj4A-3bvcA:
undetectable		 4oj4A-3bvcA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 11 LEU A  76
LEU A  19
VAL A  84
HIS A  83
LEU A 180
 None
 1.03A 4p65C-3bvcA:
undetectable
4p65D-3bvcA:
undetectable
4p65J-3bvcA:
undetectable
4p65L-3bvcA:
undetectable		 4p65C-3bvcA:
7.57
4p65D-3bvcA:
10.24
4p65J-3bvcA:
10.24
4p65L-3bvcA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 12 CYH A  35
LEU A  80
LEU A  66
LEU A  63
ALA A  39
 None
 1.26A 4rtbA-3bvcA:
undetectable		 4rtbA-3bvcA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		4 / 7 LEU A  63
SER A  59
ILE A 107
VAL A 201
 None
 1.00A 4tvtA-3bvcA:
undetectable		 4tvtA-3bvcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 11 ASP A 104
ASN A 204
HIS A 121
HIS A 187
HIS A 119
 None
None
NI  A 304 (-3.6A)
NI  A 304 (-3.5A)
NI  A 304 (-3.6A)
 1.49A 4yhaC-3bvcA:
undetectable		 4yhaC-3bvcA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 10 ASP A 104
ASN A 204
HIS A 121
HIS A 187
HIS A 119
 None
None
NI  A 304 (-3.6A)
NI  A 304 (-3.5A)
NI  A 304 (-3.6A)
 1.40A 4yhaF-3bvcA:
undetectable		 4yhaF-3bvcA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8T_B_SAMB605_0
(GUANINE-N7
METHYLTRANSFERASE)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 11 GLY A  45
ASP A  42
ALA A  39
ASN A  52
CYH A  49
 None
 1.34A 5c8tB-3bvcA:
undetectable		 5c8tB-3bvcA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		5 / 12 PHE A 203
SER A  79
ILE A  72
LEU A 180
TYR A  15
 None
 1.38A 5ycpA-3bvcA:
undetectable		 5ycpA-3bvcA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3bvc UNCHARACTERIZED
PROTEIN ISM_01780
(Roseovarius
nubinhibens) 		3 / 3 HIS A 119
HIS A 187
HIS A 121
 NI  A 304 (-3.6A)
NI  A 304 (-3.5A)
NI  A 304 (-3.6A)
 0.46A 5zrdA-3bvcA:
undetectable		 5zrdA-3bvcA:
17.85