SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bvm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 8 HIS A  31
TYR A  28
TYR A  32
LEU A  27
 None
 1.09A 1i7zA-3bvmA:
undetectable		 1i7zA-3bvmA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 5 TYR A  77
SER A 153
THR A 222
ASN A 220
 None
 1.28A 1yvpA-3bvmA:
undetectable		 1yvpA-3bvmA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 6 TYR A  77
SER A 153
THR A 222
ASN A 220
 None
 1.17A 1yvpB-3bvmA:
undetectable		 1yvpB-3bvmA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 6 ASN A 220
ILE A 161
GLN A 157
THR A  66
 None
 1.23A 2hkkA-3bvmA:
undetectable		 2hkkA-3bvmA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 8 TYR A 112
TYR A  89
GLN A 157
SER A  87
 None
 1.15A 2xz5B-3bvmA:
undetectable
2xz5E-3bvmA:
undetectable		 2xz5B-3bvmA:
23.37
2xz5E-3bvmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 7 TYR A  85
ILE A 161
THR A  66
TYR A  51
 None
 1.04A 3tneB-3bvmA:
undetectable		 3tneB-3bvmA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		3 / 3 TYR A  90
ASP A  55
ASP A  62
 None
 0.86A 4a6eA-3bvmA:
undetectable		 4a6eA-3bvmA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 7 LEU A 214
THR A 109
THR A  66
VAL A  64
 None
 0.80A 4ik7A-3bvmA:
undetectable		 4ik7A-3bvmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 8 LEU A 214
THR A 109
THR A  66
VAL A  64
 None
 0.78A 4ik7B-3bvmA:
undetectable		 4ik7B-3bvmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 7 GLY A  86
ASP A 219
MET A 216
TYR A 217
 None
 0.81A 6ag0A-3bvmA:
undetectable		 6ag0A-3bvmA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 7 GLY A  86
ASP A 219
MET A 216
TYR A 217
 None
 0.84A 6ag0C-3bvmA:
undetectable		 6ag0C-3bvmA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		5 / 6 TYR A 174
ILE A 168
ALA A 163
ARG A 164
ASP A 199
 None
 1.45A 6hu9m-3bvmA:
undetectable
6hu9q-3bvmA:
undetectable		 6hu9m-3bvmA:
17.58
6hu9q-3bvmA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 3bvm ENTEROTOXIN TYPE C-3
(Staphylococcus
aureus) 		4 / 5 GLY A 184
LEU A 234
SER A 179
TYR A 174
 None
 1.12A 6ji6A-3bvmA:
undetectable		 6ji6A-3bvmA:
23.13