SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bvp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3bvp TP901-1 INTEGRASE
(Lactococcus
phage
TP901-1) 		4 / 5 ALA A   6
TYR A   8
ILE A   7
ASP A  47
 None
 1.26A 1upfA-3bvpA:
undetectable		 1upfA-3bvpA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3bvp TP901-1 INTEGRASE
(Lactococcus
phage
TP901-1) 		4 / 5 ALA A   6
TYR A   8
ILE A   7
ASP A  47
 None
 1.10A 1upfC-3bvpA:
undetectable		 1upfC-3bvpA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bvp TP901-1 INTEGRASE
(Lactococcus
phage
TP901-1) 		4 / 7 GLY A 119
SER A 107
PHE A 122
GLU A 110
 None
 1.02A 2c8aB-3bvpA:
undetectable		 2c8aB-3bvpA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bvp TP901-1 INTEGRASE
(Lactococcus
phage
TP901-1) 		4 / 7 GLY A 119
SER A 107
PHE A 122
GLU A 110
 None
 0.98A 2c8aD-3bvpA:
undetectable		 2c8aD-3bvpA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3bvp TP901-1 INTEGRASE
(Lactococcus
phage
TP901-1) 		3 / 4 SER A 107
GLY A  52
GLU A  56
 None
 0.69A 3raeA-3bvpA:
undetectable
3raeC-3bvpA:
3.5		 3raeA-3bvpA:
15.38
3raeC-3bvpA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 3bvp TP901-1 INTEGRASE
(Lactococcus
phage
TP901-1) 		3 / 4 SER A 107
GLY A  52
GLU A  56
 None
 0.60A 4juoA-3bvpA:
undetectable
4juoC-3bvpA:
3.5		 4juoA-3bvpA:
15.38
4juoC-3bvpA:
11.41