SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bw8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 4 ILE A  38
ASP A  72
LEU A 176
ARG A  45
 None
 1.25A 2a7qA-3bw8A:
undetectable		 2a7qA-3bw8A:
22.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 7 ARG A  88
SER A 134
ARG A 146
GLN A 172
GLU A 174
 None
 0.59A 2c8aA-3bw8A:
32.4		 2c8aA-3bw8A:
59.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 7 ARG A  88
SER A 134
PHE A 143
GLU A 174
 None
 1.27A 2c8aA-3bw8A:
32.4		 2c8aA-3bw8A:
59.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 7 SER A 134
SER A 136
GLN A 172
GLU A 174
 None
 0.78A 2c8aA-3bw8A:
32.4		 2c8aA-3bw8A:
59.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 7 ARG A  88
GLY A  89
SER A 134
ARG A 146
GLU A 174
 None
 0.33A 2c8aB-3bw8A:
31.4		 2c8aB-3bw8A:
59.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 6 ARG A  88
SER A 134
ARG A 146
GLU A 174
 None
 0.30A 2c8aC-3bw8A:
30.6		 2c8aC-3bw8A:
59.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 6 ARG A  88
SER A 134
PHE A 143
GLU A 174
 None
 1.36A 2c8aC-3bw8A:
30.6		 2c8aC-3bw8A:
59.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 7 ARG A  88
GLY A  89
SER A 134
ARG A 146
GLU A 174
 None
 0.38A 2c8aD-3bw8A:
31.3		 2c8aD-3bw8A:
59.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 7 GLY A  89
SER A 134
SER A 136
GLU A 174
 None
 0.91A 2c8aD-3bw8A:
31.3		 2c8aD-3bw8A:
59.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		3 / 3 ARG A 127
GLY A  96
PRO A  97
 None
 0.64A 2hreD-3bw8A:
undetectable		 2hreD-3bw8A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 7 ILE A 149
ILE A 103
LEU A 104
ILE A 110
 None
 0.89A 2q83A-3bw8A:
undetectable		 2q83A-3bw8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 12 TYR A  94
ILE A 148
GLY A  89
ILE A 133
LEU A 203
 None
 1.05A 4iv0A-3bw8A:
undetectable		 4iv0A-3bw8A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		4 / 8 ASN A  42
ALA A  44
PRO A  49
GLU A 129
 None
SO4  A 206 (-3.1A)
None
None
 0.98A 4jjkA-3bw8A:
undetectable		 4jjkA-3bw8A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 12 TYR A  94
ILE A 148
GLY A  89
ILE A 133
LEU A 203
 None
 1.01A 4mwzB-3bw8A:
undetectable		 4mwzB-3bw8A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 12 LEU A 104
GLY A  93
ASP A  98
ILE A 110
ILE A 103
 None
 0.86A 5e5jB-3bw8A:
undetectable		 5e5jB-3bw8A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		3 / 3 ILE A 148
PRO A 147
ILE A 197
 None
 0.45A 5hw8F-3bw8A:
undetectable		 5hw8F-3bw8A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 12 LEU A  86
SER A 186
ARG A  88
ILE A 199
ASP A  90
 None
 1.47A 6bxnA-3bw8A:
undetectable		 6bxnA-3bw8A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		5 / 12 LEU A 177
SER A 186
ARG A  88
ILE A 199
ASP A  90
 None
 1.47A 6bxnA-3bw8A:
undetectable		 6bxnA-3bw8A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Hathewaya
limosa) 		3 / 3 LEU A 177
ASP A 126
ILE A 185
 None
 0.62A 6dh0B-3bw8A:
undetectable		 6dh0B-3bw8A:
17.62