SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bwg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		4 / 5 ILE A  56
LEU A  49
ALA A   8
GLU A  12
 None
 1.18A 1xvaA-3bwgA:
undetectable
1xvaB-3bwgA:
undetectable		 1xvaA-3bwgA:
21.55
1xvaB-3bwgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		4 / 8 TYR A 141
ASP A 214
SER A 216
TYR A 215
 None
 1.35A 2bteD-3bwgA:
undetectable		 2bteD-3bwgA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		3 / 3 ASN A 111
TYR A 200
SER A 203
 None
 0.89A 2gvcB-3bwgA:
undetectable		 2gvcB-3bwgA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		3 / 3 ASN A 111
TYR A 200
SER A 203
 None
 0.93A 2gvcE-3bwgA:
undetectable		 2gvcE-3bwgA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		5 / 12 GLU A 185
GLU A 186
TYR A 215
TYR A 122
TYR A 136
 None
EDO  A 240 (-4.1A)
None
None
EDO  A 240 (-4.5A)
 1.35A 3ckzA-3bwgA:
undetectable		 3ckzA-3bwgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		4 / 8 ALA A  55
GLU A  12
ILE A  11
ILE A  43
 None
 0.91A 4kttB-3bwgA:
undetectable		 4kttB-3bwgA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		5 / 12 LEU A 175
LEU A 177
ILE A 201
VAL A 229
LEU A  78
 None
 0.93A 4y0sA-3bwgA:
undetectable		 4y0sA-3bwgA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3bwg UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YYDK
(Bacillus
subtilis) 		5 / 12 ASP A 214
LEU A 199
LEU A  77
SER A 173
LEU A 177
 None
EDO  A 238 (-4.0A)
None
None
None
 1.22A 5hnyB-3bwgA:
undetectable		 5hnyB-3bwgA:
19.43