SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bwh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		7 / 9 ILE A  71
PHE A  83
GLY A 107
TYR A 109
ILE A 153
GLU A 158
ARG A 161
 None
None
EDO  A 253 (-4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
 0.37A 1mrgA-3bwhA:
39.0		 1mrgA-3bwhA:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		7 / 8 ILE A  71
GLY A 107
TYR A 109
ILE A 153
SER A 157
GLU A 158
ARG A 161
 None
EDO  A 253 (-4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
 0.28A 1mrjA-3bwhA:
40.8		 1mrjA-3bwhA:
61.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		4 / 8 TYR A  70
TYR A 109
SER A 157
GLU A 158
 EDO  A 253 ( 4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 ( 4.6A)
 0.83A 1mrjA-3bwhA:
40.8		 1mrjA-3bwhA:
61.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		4 / 7 GLU A 158
GLU A 187
ILE A 183
LEU A 150
 EDO  A 253 ( 4.6A)
None
None
None
 1.40A 1q0yH-3bwhA:
undetectable
1q0yL-3bwhA:
undetectable		 1q0yH-3bwhA:
18.08
1q0yL-3bwhA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		6 / 12 ALA A  62
LEU A 137
LEU A 152
ILE A 153
PHE A  83
LEU A 103
 None
None
None
EDO  A 253 ( 4.1A)
None
None
 1.29A 1xdkF-3bwhA:
undetectable		 1xdkF-3bwhA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		5 / 12 PHE A  47
LEU A  93
ASP A  65
VAL A  66
VAL A  41
 None
 1.05A 2g70A-3bwhA:
undetectable		 2g70A-3bwhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		5 / 12 PHE A  47
LEU A  93
ASP A  65
VAL A  66
VAL A  41
 None
 1.13A 2g70B-3bwhA:
undetectable		 2g70B-3bwhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		5 / 12 PHE A  47
LEU A  93
ASP A  65
VAL A  66
VAL A  41
 None
 1.08A 2g72A-3bwhA:
undetectable		 2g72A-3bwhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		5 / 12 PHE A  47
LEU A  93
ILE A  48
VAL A  66
VAL A  41
 None
 1.20A 2g72B-3bwhA:
undetectable		 2g72B-3bwhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		4 / 8 TYR A  81
TYR A  74
ALA A 148
ALA A 144
 None
 0.99A 2wx2B-3bwhA:
undetectable		 2wx2B-3bwhA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		4 / 8 TYR A  81
TYR A  74
ALA A 148
ALA A 144
 None
 0.90A 3l4dA-3bwhA:
undetectable		 3l4dA-3bwhA:
17.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		7 / 10 TYR A  70
ILE A  71
ASN A 108
TYR A 109
ILE A 153
GLU A 158
ARG A 161
 EDO  A 253 ( 4.5A)
None
None
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
 0.82A 3u6tA-3bwhA:
39.3		 3u6tA-3bwhA:
58.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		4 / 6 ALA A 146
LEU A 150
VAL A 151
GLU A 124
 None
 0.94A 4g24A-3bwhA:
undetectable		 4g24A-3bwhA:
17.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		5 / 5 TYR A  70
ILE A  71
ASN A 108
TYR A 109
ILE A 153
 EDO  A 253 ( 4.5A)
None
None
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
 0.57A 4jtpA-3bwhA:
39.3		 4jtpA-3bwhA:
58.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		5 / 5 TYR A  70
ASN A 108
TYR A 109
ILE A 153
ARG A 161
 EDO  A 253 ( 4.5A)
None
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 (-2.9A)
 0.43A 4o0oA-3bwhA:
39.3		 4o0oA-3bwhA:
58.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		8 / 9 TYR A  70
ILE A  71
PHE A  83
GLY A 107
TYR A 109
ILE A 153
GLU A 158
ARG A 161
 EDO  A 253 ( 4.5A)
None
None
EDO  A 253 (-4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
 0.48A 4yp2B-3bwhA:
39.4		 4yp2B-3bwhA:
58.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		8 / 9 TYR A  70
ILE A  71
PHE A  83
GLY A 107
TYR A 109
ILE A 153
GLU A 158
ARG A 161
 EDO  A 253 ( 4.5A)
None
None
EDO  A 253 (-4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
 0.45A 5cf9B-3bwhA:
39.5		 5cf9B-3bwhA:
58.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		3 / 3 THR A  76
SER A  75
TYR A  74
 None
 0.79A 5jsdA-3bwhA:
undetectable		 5jsdA-3bwhA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		3 / 3 THR A  76
SER A  75
TYR A  74
 None
 0.81A 5jsdB-3bwhA:
undetectable		 5jsdB-3bwhA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		3 / 3 THR A  76
SER A  75
TYR A  74
 None
 0.79A 5jsdC-3bwhA:
undetectable		 5jsdC-3bwhA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		3 / 3 THR A  76
SER A  75
TYR A  74
 None
 0.81A 5jseA-3bwhA:
undetectable		 5jseA-3bwhA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		3 / 3 THR A  76
SER A  75
TYR A  74
 None
 0.80A 5jseB-3bwhA:
undetectable		 5jseB-3bwhA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		3 / 3 THR A  76
SER A  75
TYR A  74
 None
 0.80A 5jseC-3bwhA:
undetectable		 5jseC-3bwhA:
16.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		5 / 6 TYR A  70
TYR A 109
ILE A 153
GLU A 158
ARG A 161
 EDO  A 253 ( 4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
 0.45A 5z3jA-3bwhA:
35.6		 5z3jA-3bwhA:
36.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3bwh CUCURMOSIN
(Cucurbita
moschata) 		3 / 3 ALA A  63
PHE A  82
GLN A 100
 None
 0.83A 6eceA-3bwhA:
undetectable		 6eceA-3bwhA:
21.05