SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bwn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 279
TYR A  35
TYR A  38
LEU A 263
LEU A  80
 None
 1.23A 1e7wA-3bwnA:
undetectable		 1e7wA-3bwnA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 ALA A 150
VAL A 122
TRP A 146
 None
 0.94A 1ng8B-3bwnA:
undetectable		 1ng8B-3bwnA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 ALA A 150
VAL A 122
TRP A 146
 None
 0.95A 1nrmA-3bwnA:
undetectable		 1nrmA-3bwnA:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 ALA A 150
VAL A 122
TRP A 146
 None
 0.95A 1nrmB-3bwnA:
undetectable		 1nrmB-3bwnA:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 ALA A 150
VAL A 122
TRP A 146
 None
 0.93A 1nruA-3bwnA:
undetectable		 1nruA-3bwnA:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 ALA A 150
VAL A 122
TRP A 146
 None
 0.93A 1nruB-3bwnA:
undetectable		 1nruB-3bwnA:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 279
TYR A  35
TYR A  38
LEU A 263
LEU A  80
 None
 1.39A 1p33A-3bwnA:
undetectable		 1p33A-3bwnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 279
TYR A  35
TYR A  38
LEU A 263
LEU A  80
 None
 1.35A 1p33B-3bwnA:
undetectable		 1p33B-3bwnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQJ_A_TRPA650_0
(TRYPTOPHAN
HALOGENASE, PRNA)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 ILE A 218
ILE A  77
HIS A  81
PHE A 280
ASN A  86
 None
 1.36A 2aqjA-3bwnA:
0.0		 2aqjA-3bwnA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKC_A_TRPA1520_0
(FLAVIN-DEPENDENT
TRYPTOPHAN
HALOGENASE PRNA)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 10 ILE A 218
ILE A  77
HIS A  81
PHE A 280
ASN A  86
 None
 1.37A 2jkcA-3bwnA:
0.0		 2jkcA-3bwnA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2002_0
(TRYPTOPHAN
HALOGENASE)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 218
ILE A  77
HIS A  81
PHE A 280
ASN A  86
 None
 1.37A 2oa1A-3bwnA:
1.1		 2oa1A-3bwnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2003_0
(TRYPTOPHAN
HALOGENASE)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 218
ILE A  77
HIS A  81
PHE A 280
ASN A  86
 None
 1.37A 2oa1B-3bwnA:
0.8		 2oa1B-3bwnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 LEU A 263
LEU A 230
PRO A 197
GLY A  85
 None
 1.01A 2po5A-3bwnA:
undetectable		 2po5A-3bwnA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 ILE A 218
TRP A 228
LEU A  73
ILE A 226
 None
 0.93A 2q83B-3bwnA:
undetectable		 2q83B-3bwnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 SER A  60
PHE A 215
GLY A 227
ILE A  77
 None
 0.78A 3aodA-3bwnA:
undetectable		 3aodA-3bwnA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 ILE A  77
VAL A  83
GLY A  85
PRO A 197
LEU A 230
 None
 1.13A 3em0B-3bwnA:
undetectable		 3em0B-3bwnA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 PRO A 201
SER A 320
ASN A 315
 None
 0.84A 3lslG-3bwnA:
undetectable		 3lslG-3bwnA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PRO A 197
TYR A  35
ILE A 202
PHE A 213
ILE A 218
 None
 1.40A 3q5pA-3bwnA:
undetectable		 3q5pA-3bwnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 7 LEU A 330
VAL A 364
VAL A 298
LEU A 367
MET A 287
 None
 1.44A 3rgfA-3bwnA:
undetectable		 3rgfA-3bwnA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 TYR A 309
MET A 286
LEU A 367
 None
 0.99A 3vw1D-3bwnA:
undetectable		 3vw1D-3bwnA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 TYR A 199
THR A  89
LEU A 230
THR A 164
 None
None
None
PMP  A1001 (-3.5A)
 1.41A 4mbsB-3bwnA:
undetectable		 4mbsB-3bwnA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 TYR A 199
GLY A  30
SER A 365
LEU A 367
 None
 1.28A 5bphC-3bwnA:
undetectable		 5bphC-3bwnA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 TYR A 199
GLY A  30
SER A 365
LEU A 367
 None
 1.30A 5bphD-3bwnA:
undetectable		 5bphD-3bwnA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 212
LEU A  65
LEU A 103
ILE A 245
ALA A 110
 None
 0.90A 5ienB-3bwnA:
undetectable		 5ienB-3bwnA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3bwn L-TRYPTOPHAN
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 GLN A 102
ILE A  94
ALA A 237
VAL A 236
 None
 1.02A 6hu9a-3bwnA:
1.8
6hu9e-3bwnA:
undetectable		 6hu9a-3bwnA:
21.64
6hu9e-3bwnA:
16.16