SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bwq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		5 / 12 ILE A 288
GLY A 156
ALA A 112
ASP A 198
LEU A 197
 None
 1.21A 1i9gA-3bwqA:
undetectable		 1i9gA-3bwqA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		5 / 12 LEU A 290
ILE A 288
VAL A 243
LEU A 244
GLY A 251
 None
 0.91A 1uakA-3bwqA:
undetectable		 1uakA-3bwqA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		4 / 8 GLY A 251
GLU A 111
ALA A 112
ASN A 217
 None
 0.76A 2dtjA-3bwqA:
undetectable
2dtjB-3bwqA:
undetectable		 2dtjA-3bwqA:
21.01
2dtjB-3bwqA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		4 / 8 ILE A  32
GLU A 216
LYS A 255
GLU A 157
 None
 0.95A 2j9dJ-3bwqA:
undetectable
2j9dK-3bwqA:
undetectable
2j9dL-3bwqA:
undetectable		 2j9dJ-3bwqA:
18.55
2j9dK-3bwqA:
18.55
2j9dL-3bwqA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		4 / 8 LYS A 255
GLU A 157
ILE A  32
GLU A 216
 None
 0.93A 2j9dJ-3bwqA:
undetectable
2j9dK-3bwqA:
undetectable
2j9dL-3bwqA:
undetectable		 2j9dJ-3bwqA:
18.55
2j9dK-3bwqA:
18.55
2j9dL-3bwqA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		5 / 10 GLY A 227
GLY A 226
THR A 225
TYR A 224
GLU A 228
 None
 1.17A 3fw1A-3bwqA:
undetectable		 3fw1A-3bwqA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		4 / 4 PRO A 210
TYR A 220
GLY A 222
THR A 223
 None
 1.44A 3ib0A-3bwqA:
undetectable		 3ib0A-3bwqA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		4 / 6 PHE A 152
PHE A 221
THR A 117
VAL A 115
 None
 1.21A 3lb3A-3bwqA:
undetectable		 3lb3A-3bwqA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		4 / 6 PHE A 152
PHE A 221
THR A 117
VAL A 115
 None
 1.21A 3lb3B-3bwqA:
undetectable		 3lb3B-3bwqA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		5 / 7 THR A 218
PRO A 210
ASN A 215
GLY A 222
THR A 223
 None
 1.49A 3tajA-3bwqA:
undetectable		 3tajA-3bwqA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		4 / 7 GLY A 227
GLY A 226
TYR A 224
GLU A 228
 None
 0.97A 4fgkB-3bwqA:
undetectable		 4fgkB-3bwqA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		5 / 12 CYH A  49
LEU A  51
THR A 218
ILE A  93
ALA A  91
 None
 1.11A 5eypB-3bwqA:
undetectable		 5eypB-3bwqA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		5 / 12 CYH A  49
LEU A  51
THR A 218
ILE A  93
ALA A  91
 None
 1.16A 5xiwD-3bwqA:
undetectable		 5xiwD-3bwqA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		5 / 12 LEU A 290
ILE A 288
VAL A 243
LEU A 244
GLY A 251
 None
 0.88A 5zhmB-3bwqA:
undetectable		 5zhmB-3bwqA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3bwq CAPSID PROTEIN VP1
(Macaca
mulatta
polyomavirus
1) 		3 / 3 GLN A 187
TYR A 168
ASN A 167
 None
 0.99A 6dwdC-3bwqA:
undetectable		 6dwdC-3bwqA:
18.80