SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3bwu OUTER MEMBRANE USHER
PROTEIN FIMD,
N-TERMINAL DOMAIN
(Escherichia
coli) 		4 / 7 GLY D  31
PRO D  30
ASP D  18
ALA D  17
 None
 0.92A 1gxsA-3bwuD:
undetectable
1gxsB-3bwuD:
undetectable		 1gxsA-3bwuD:
21.17
1gxsB-3bwuD:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3bwu OUTER MEMBRANE USHER
PROTEIN FIMD,
N-TERMINAL DOMAIN
(Escherichia
coli) 		3 / 3 MET D  44
ASN D 122
GLN D 117
 None
 0.92A 1xoqB-3bwuD:
undetectable		 1xoqB-3bwuD:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3bwu OUTER MEMBRANE USHER
PROTEIN FIMD,
N-TERMINAL DOMAIN
(Escherichia
coli) 		3 / 3 VAL D 106
ASP D 105
GLU D  27
 None
 0.74A 2qeuA-3bwuD:
undetectable		 2qeuA-3bwuD:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3bwu OUTER MEMBRANE USHER
PROTEIN FIMD,
N-TERMINAL DOMAIN
(Escherichia
coli) 		3 / 3 VAL D 106
ASP D 105
GLU D  27
 None
 0.74A 2qeuC-3bwuD:
undetectable		 2qeuC-3bwuD:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3bwu OUTER MEMBRANE USHER
PROTEIN FIMD,
N-TERMINAL DOMAIN
(Escherichia
coli) 		4 / 5 VAL D  35
ILE D 115
TYR D  43
MET D  44
 None
 0.90A 4c8bA-3bwuD:
undetectable		 4c8bA-3bwuD:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3bwu OUTER MEMBRANE USHER
PROTEIN FIMD,
N-TERMINAL DOMAIN
(Escherichia
coli) 		3 / 3 TYR D  43
MET D  44
ILE D 115
 None
 0.66A 4c8bB-3bwuD:
undetectable		 4c8bB-3bwuD:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 3bwu PROTEIN FIMF
(Escherichia
coli) 		4 / 6 LEU F  96
LEU F 131
PHE F  25
THR F  23
 None
 1.03A 4udaA-3bwuF:
undetectable		 4udaA-3bwuF:
21.09