SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bx8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 1.02A 1t85A-3bx8A:
undetectable		 1t85A-3bx8A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.99A 1t87A-3bx8A:
undetectable		 1t87A-3bx8A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.95A 1yrcA-3bx8A:
undetectable		 1yrcA-3bx8A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.96A 1yrdA-3bx8A:
undetectable		 1yrdA-3bx8A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 6 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.98A 2feuA-3bx8A:
undetectable		 2feuA-3bx8A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.97A 2feuB-3bx8A:
undetectable		 2feuB-3bx8A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 8 PHE A  27
THR A  54
THR A 136
VAL A 108
 None
1PE  A 179 ( 4.7A)
None
None
 0.97A 2qbmA-3bx8A:
undetectable		 2qbmA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		5 / 8 PHE A  83
TYR A  56
THR A  54
VAL A 121
THR A 136
 None
None
1PE  A 179 ( 4.7A)
None
None
 1.05A 2qbmA-3bx8A:
undetectable		 2qbmA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 6 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 1.02A 2zuhA-3bx8A:
undetectable		 2zuhA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 6 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 1.00A 2zuiA-3bx8A:
undetectable		 2zuiA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.96A 2zwtA-3bx8A:
undetectable		 2zwtA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.96A 2zwuA-3bx8A:
undetectable		 2zwuA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 1.00A 3fwfA-3bx8A:
undetectable		 3fwfA-3bx8A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 1.00A 3fwfB-3bx8A:
undetectable		 3fwfB-3bx8A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.96A 3fwiA-3bx8A:
undetectable		 3fwiA-3bx8A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.98A 3fwjA-3bx8A:
undetectable		 3fwjA-3bx8A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.99A 3l63A-3bx8A:
undetectable		 3l63A-3bx8A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.94A 3wrhA-3bx8A:
undetectable		 3wrhA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.98A 3wrjA-3bx8A:
undetectable		 3wrjA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.97A 3wrlA-3bx8A:
undetectable		 3wrlA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 1.01A 3wrlE-3bx8A:
undetectable		 3wrlE-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.97A 3wrmA-3bx8A:
undetectable		 3wrmA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.99A 3wrmF-3bx8A:
undetectable		 3wrmF-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 8 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.93A 4iizB-3bx8A:
undetectable		 4iizB-3bx8A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 8 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.95A 4ik6B-3bx8A:
undetectable		 4ik6B-3bx8A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 0.98A 4l4gA-3bx8A:
undetectable		 4l4gA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
None
1PE  A 179 ( 4.7A)
None
 1.03A 5wk9A-3bx8A:
undetectable		 5wk9A-3bx8A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3bx8 ENGINEERED HUMAN
LIPOCALIN 2
(Homo
sapiens) 		5 / 12 VAL A 120
VAL A  33
GLY A  35
PHE A 123
VAL A 108
 None
None
None
1PE  A 179 (-3.8A)
None
 1.20A 6a94B-3bx8A:
undetectable		 6a94B-3bx8A:
18.38