SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bxa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3bxa FAR-RED FLUORESCENT
PROTEIN MKATE
(Entacmaea
quadricolor) 		4 / 5 PRO A 149
LEU A 154
THR A 144
ARG A 220
 None
 1.07A 1i2wA-3bxaA:
undetectable		 1i2wA-3bxaA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3bxa FAR-RED FLUORESCENT
PROTEIN MKATE
(Entacmaea
quadricolor) 		4 / 7 LEU A 147
ILE A  70
ILE A  76
PHE A  88
 None
 0.90A 1uwjA-3bxaA:
undetectable		 1uwjA-3bxaA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3bxa FAR-RED FLUORESCENT
PROTEIN MKATE
(Entacmaea
quadricolor) 		4 / 6 ARG A 197
GLY A 156
THR A 176
ARG A  92
 NRQ  A  63 ( 3.9A)
None
None
NRQ  A  63 ( 2.6A)
 1.08A 2f7fA-3bxaA:
undetectable		 2f7fA-3bxaA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 3bxa FAR-RED FLUORESCENT
PROTEIN MKATE
(Entacmaea
quadricolor) 		3 / 3 GLY A 156
ARG A 157
TYR A 178
 None
 0.82A 2opxA-3bxaA:
undetectable		 2opxA-3bxaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 3bxa FAR-RED FLUORESCENT
PROTEIN MKATE
(Entacmaea
quadricolor) 		5 / 12 GLN A 134
GLY A 139
VAL A 165
ASP A  56
ALA A  54
 None
 1.18A 3d91B-3bxaA:
undetectable		 3d91B-3bxaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3bxa FAR-RED FLUORESCENT
PROTEIN MKATE
(Entacmaea
quadricolor) 		3 / 3 ILE A  70
VAL A 195
ARG A 197
 None
None
NRQ  A  63 ( 3.9A)
 0.49A 3p73A-3bxaA:
1.4		 3p73A-3bxaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3bxa FAR-RED FLUORESCENT
PROTEIN MKATE
(Entacmaea
quadricolor) 		3 / 3 LYS A 182
PRO A 183
LYS A 185
 None
 1.06A 5y9yA-3bxaA:
undetectable		 5y9yA-3bxaA:
21.53