SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bxj'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_A_CHDA1503_0 (FERROCHELATASE)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	3 / 3	LEU A 699 PRO A 698 LEU A 702	None	0.51A	1hrkA-3bxjA: undetectable	1hrkA-3bxjA: 23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_B_BEZB504_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	4 / 7	LEU A 595 ILE A 499 ALA A 586 ILE A 615	None	0.93A	1oniB-3bxjA: undetectable 1oniC-3bxjA: undetectable	1oniB-3bxjA: 14.08 1oniC-3bxjA: 14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_B_VIAB902_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 12	ALA A 435 ILE A 439 LEU A 710 ILE A 396 PHE A 405	None	1.10A	2h42B-3bxjA: undetectable	2h42B-3bxjA: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OK6_H_BEZH2001_0 (AROMATIC AMINE DEHYDROGENASE, LARGE SUBUNIT AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 10	LEU A 638 ASN A 635 GLY A 632 LEU A 631 PHE A 637	None	1.29A	2ok6A-3bxjA: undetectable 2ok6H-3bxjA: undetectable	2ok6A-3bxjA: 21.25 2ok6H-3bxjA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD5_B_CHDB1104_0 (FERROCHELATASE)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	3 / 3	LEU A 397 PRO A 398 LEU A 401	None	0.43A	2qd5B-3bxjA: undetectable	2qd5B-3bxjA: 23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_C_TOPC200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 11	LEU A 436 VAL A 409 LEU A 681 PHE A 405 THR A 443	None	1.34A	3fl9C-3bxjA: undetectable	3fl9C-3bxjA: 16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_H_TOPH200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 9	LEU A 436 VAL A 409 LEU A 681 PHE A 405 THR A 443	None	1.37A	3fl9H-3bxjA: undetectable	3fl9H-3bxjA: 16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NUV_A_ASDA126_1 (STEROID DELTA-ISOMERASE)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 12	SER A 575 LEU A 649 PHE A 546 VAL A 539 MET A 483	None	1.48A	3nuvA-3bxjA: undetectable	3nuvA-3bxjA: 12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	3 / 3	LEU A 397 PRO A 398 LEU A 401	None	0.49A	3w1wB-3bxjA: undetectable	3w1wB-3bxjA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESH_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 12	ALA A 679 LEU A 680 ILE A 486 TYR A 482 GLY A 666	None	1.23A	5eshA-3bxjA: undetectable	5eshA-3bxjA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V0V_A_8QPA612_1 (SERUM ALBUMIN)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 12	GLU A 431 LEU A 416 LEU A 681 ILE A 439 ALA A 435	None	1.21A	5v0vA-3bxjA: 2.0	5v0vA-3bxjA: 22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H1L_A_FJQA501_0 (BIFUNCTIONAL CYTOCHROME P450/NADPH--P450 REDUCTASE)	3bxj	RAS GTPASE-ACTIVATING PROTEIN SYNGAP (Rattus norvegicus)	5 / 10	ALA A 535 LEU A 536 VAL A 539 PHE A 648 LEU A 583	None	1.00A	6h1lA-3bxjA: undetectable	6h1lA-3bxjA: 21.61