SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bxp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GYX_A_BEZA1077_0
(HYPOTHETICAL PROTEIN
YDCE)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 7 CYH A  40
PHE A 115
PRO A  41
SER A  49
 None
 1.49A 1gyxA-3bxpA:
0.3
1gyxB-3bxpA:
0.3		 1gyxA-3bxpA:
13.72
1gyxB-3bxpA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_2
(MINERALOCORTICOID
RECEPTOR)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 4 LEU A 112
TRP A 265
LEU A 271
MET A  65
 None
 1.34A 2oaxE-3bxpA:
0.0		 2oaxE-3bxpA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 8 ALA A 117
TYR A  72
HIS A 120
GLY A  44
 None
 0.73A 2zm9A-3bxpA:
undetectable		 2zm9A-3bxpA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 8 ILE A 150
HIS A 147
TYR A 212
GLY A 127
 None
 0.85A 3b9lA-3bxpA:
undetectable		 3b9lA-3bxpA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 5 ILE A 150
HIS A 147
TYR A 212
GLY A 127
 None
 0.90A 3b9mA-3bxpA:
undetectable		 3b9mA-3bxpA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 7 LEU A 152
ALA A 193
THR A 223
VAL A 221
 None
 0.82A 3d2tA-3bxpA:
undetectable		 3d2tA-3bxpA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 8 ALA A  91
THR A  92
GLY A 118
PRO A  41
 None
 0.94A 3ny4A-3bxpA:
undetectable		 3ny4A-3bxpA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 7 LEU A 152
ALA A 193
THR A 223
VAL A 221
 None
 0.76A 3ozkB-3bxpA:
undetectable		 3ozkB-3bxpA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 7 LEU A 152
ALA A 193
THR A 223
VAL A 221
 None
 0.68A 4ik7A-3bxpA:
undetectable		 4ik7A-3bxpA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 8 LEU A 152
ALA A 193
THR A 223
VAL A 221
 None
 0.76A 4ik7B-3bxpA:
undetectable		 4ik7B-3bxpA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		4 / 7 ILE A 151
LEU A  89
ILE A  39
MET A  37
 None
 0.98A 4xumA-3bxpA:
undetectable		 4xumA-3bxpA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		5 / 12 GLN A  73
TRP A  84
ALA A  12
ASN A   9
TYR A 143
 None
EPE  A 277 (-3.9A)
None
None
None
 1.39A 5cxvA-3bxpA:
undetectable		 5cxvA-3bxpA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		5 / 9 ILE A  39
GLY A 119
PHE A 115
TYR A  82
ALA A  85
 None
 1.42A 5x66C-3bxpA:
undetectable		 5x66C-3bxpA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3bxp PUTATIVE
LIPASE/ESTERASE
(Lactobacillus
plantarum) 		5 / 10 ILE A  39
GLY A 119
PHE A 115
TYR A  82
ALA A  85
 None
 1.44A 5x66D-3bxpA:
undetectable		 5x66D-3bxpA:
24.12