SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bxv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		4 / 6 PRO A   2
ASP A  82
ASP A  85
TYR A 305
 None
 1.46A 1hpkA-3bxvA:
undetectable		 1hpkA-3bxvA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		5 / 11 PHE A  54
LEU A  52
ALA A 162
TYR A 289
HIS A 166
 None
 1.29A 1qabE-3bxvA:
0.0		 1qabE-3bxvA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		5 / 11 VAL A 252
ILE A 290
GLY A 164
ILE A 180
LEU A 184
 None
 1.06A 1z11A-3bxvA:
undetectable		 1z11A-3bxvA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		5 / 10 VAL A 252
ILE A 290
GLY A 164
ILE A 180
LEU A 184
 None
 1.12A 1z11D-3bxvA:
undetectable		 1z11D-3bxvA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		4 / 6 LEU A  75
MET A 108
MET A  22
LEU A  13
 None
 1.45A 2oz7A-3bxvA:
undetectable		 2oz7A-3bxvA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		4 / 5 LEU A  52
GLY A 164
ILE A 293
ILE A 292
 None
 0.74A 2q9rA-3bxvA:
undetectable		 2q9rA-3bxvA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		3 / 3 PRO A   4
PHE A  40
LYS A  81
 None
 1.15A 3bjwG-3bxvA:
undetectable		 3bjwG-3bxvA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		5 / 12 ALA A 190
TYR A 121
ASP A 123
TYR A 273
GLY A 263
 None
 1.44A 3vwqA-3bxvA:
undetectable		 3vwqA-3bxvA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		4 / 6 GLN A 107
PRO A  17
PHE A  20
PHE A  23
 None
 1.01A 4fgkA-3bxvA:
undetectable		 4fgkA-3bxvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		5 / 11 ALA A 190
VAL A 267
PRO A 288
PHE A  54
ILE A 290
 None
 1.23A 4j4vA-3bxvA:
undetectable		 4j4vA-3bxvA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		4 / 5 TYR A  77
LEU A 306
GLU A 253
VAL A 151
 None
 1.15A 4nkvA-3bxvA:
undetectable		 4nkvA-3bxvA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3bxv SULFUR
OXYGENASE/REDUCTASE
(Acidianus
tengchongensis) 		4 / 6 TYR A  77
LEU A 306
GLU A 253
VAL A 151
 None
 1.14A 4nkvC-3bxvA:
undetectable		 4nkvC-3bxvA:
21.10