SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 11 ALA A 498
THR A 446
LEU A 423
LEU A 554
GLY A 553
None
1.12A 1b02A-3bxzA:
undetectable
1b02A-3bxzA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 1lzzA-3bxzA:
undetectable
1lzzB-3bxzA:
undetectable
1lzzA-3bxzA:
20.85
1lzzB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 1lzzA-3bxzA:
undetectable
1lzzB-3bxzA:
undetectable
1lzzA-3bxzA:
20.85
1lzzB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 1mmwA-3bxzA:
undetectable
1mmwB-3bxzA:
1.2
1mmwA-3bxzA:
20.85
1mmwB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 LEU A  89
LEU A 114
ILE A  64
MET A  21
None
0.95A 1n13I-3bxzA:
undetectable
1n13L-3bxzA:
undetectable
1n13I-3bxzA:
7.58
1n13L-3bxzA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 1om4A-3bxzA:
undetectable
1om4B-3bxzA:
undetectable
1om4A-3bxzA:
20.85
1om4B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 1p6iA-3bxzA:
0.3
1p6iB-3bxzA:
undetectable
1p6iA-3bxzA:
20.85
1p6iB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.50A 1p6jA-3bxzA:
undetectable
1p6jB-3bxzA:
undetectable
1p6jA-3bxzA:
20.85
1p6jB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 1p6jA-3bxzA:
undetectable
1p6jB-3bxzA:
undetectable
1p6jA-3bxzA:
20.85
1p6jB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.44A 1p6kA-3bxzA:
undetectable
1p6kB-3bxzA:
undetectable
1p6kA-3bxzA:
20.85
1p6kB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 1rs7A-3bxzA:
undetectable
1rs7B-3bxzA:
undetectable
1rs7A-3bxzA:
20.85
1rs7B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
3 / 3 GLY A 579
ASP A 580
ASN A 415
None
0.65A 1vq1A-3bxzA:
3.4
1vq1A-3bxzA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 12 GLY A 177
VAL A 128
ALA A 140
ASP A 133
ALA A 136
None
1.37A 2avdB-3bxzA:
2.2
2avdB-3bxzA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 11 ILE A 567
GLU A 397
GLY A 392
THR A 391
GLU A 210
None
None
None
None
MG  A 903 ( 4.6A)
1.25A 2fn1B-3bxzA:
undetectable
2fn1B-3bxzA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 2hx4A-3bxzA:
undetectable
2hx4B-3bxzA:
undetectable
2hx4A-3bxzA:
20.85
2hx4B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 LEU A  89
LEU A 114
ILE A  64
MET A  21
None
0.97A 2qqcA-3bxzA:
undetectable
2qqcF-3bxzA:
undetectable
2qqcA-3bxzA:
7.81
2qqcF-3bxzA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 LEU A  89
LEU A 114
ILE A  64
MET A  21
None
0.93A 2qqcG-3bxzA:
undetectable
2qqcJ-3bxzA:
undetectable
2qqcG-3bxzA:
7.81
2qqcJ-3bxzA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 6 TYR A 384
TYR A 380
TYR A 182
ILE A 214
None
1.34A 2xz5A-3bxzA:
0.0
2xz5B-3bxzA:
0.0
2xz5A-3bxzA:
17.87
2xz5B-3bxzA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 TYR A 384
TYR A 380
TYR A 182
ILE A 214
None
1.35A 2xz5B-3bxzA:
undetectable
2xz5E-3bxzA:
undetectable
2xz5B-3bxzA:
17.87
2xz5E-3bxzA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 TYR A 384
VAL A 128
TYR A 182
ILE A 214
None
1.24A 2xz5B-3bxzA:
undetectable
2xz5E-3bxzA:
undetectable
2xz5B-3bxzA:
17.87
2xz5E-3bxzA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 ILE A 214
TYR A 384
TYR A 380
TYR A 182
None
1.34A 2xz5D-3bxzA:
undetectable
2xz5E-3bxzA:
undetectable
2xz5D-3bxzA:
17.87
2xz5E-3bxzA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3b3mA-3bxzA:
undetectable
3b3mB-3bxzA:
undetectable
3b3mA-3bxzA:
20.85
3b3mB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3b3nA-3bxzA:
undetectable
3b3nB-3bxzA:
undetectable
3b3nA-3bxzA:
20.85
3b3nB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 3b3oA-3bxzA:
undetectable
3b3oB-3bxzA:
undetectable
3b3oA-3bxzA:
20.85
3b3oB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 8 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.45A 3b3pA-3bxzA:
undetectable
3b3pB-3bxzA:
undetectable
3b3pA-3bxzA:
20.85
3b3pB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
3 / 3 ASN A 179
ASP A 212
GLN A 570
None
0.80A 3eeyC-3bxzA:
2.8
3eeyC-3bxzA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
3 / 3 ASN A 179
ASP A 212
GLN A 570
None
0.80A 3eeyD-3bxzA:
2.1
3eeyD-3bxzA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
3 / 3 ASN A 179
ASP A 212
GLN A 570
None
0.80A 3eeyE-3bxzA:
undetectable
3eeyE-3bxzA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 12 ILE A  99
GLY A 389
ALA A 112
ALA A 206
VAL A 211
None
0.90A 3jb2A-3bxzA:
undetectable
3jb2A-3bxzA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 12 ILE A  99
GLY A 389
ALA A 112
ALA A 206
VAL A 211
None
1.01A 3jb3A-3bxzA:
undetectable
3jb3A-3bxzA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3jt4A-3bxzA:
undetectable
3jt4B-3bxzA:
undetectable
3jt4A-3bxzA:
20.85
3jt4B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3jt5A-3bxzA:
undetectable
3jt5B-3bxzA:
undetectable
3jt5A-3bxzA:
20.85
3jt5B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 3jt6A-3bxzA:
undetectable
3jt6B-3bxzA:
undetectable
3jt6A-3bxzA:
20.85
3jt6B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3jt7A-3bxzA:
undetectable
3jt7B-3bxzA:
undetectable
3jt7A-3bxzA:
20.85
3jt7B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3jt8A-3bxzA:
undetectable
3jt8B-3bxzA:
undetectable
3jt8A-3bxzA:
20.85
3jt8B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3n2rA-3bxzA:
undetectable
3n2rB-3bxzA:
undetectable
3n2rA-3bxzA:
20.85
3n2rB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3n5vA-3bxzA:
undetectable
3n5vB-3bxzA:
undetectable
3n5vA-3bxzA:
20.85
3n5vB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3n5yA-3bxzA:
undetectable
3n5yB-3bxzA:
undetectable
3n5yA-3bxzA:
20.85
3n5yB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3nlwA-3bxzA:
undetectable
3nlwB-3bxzA:
undetectable
3nlwA-3bxzA:
20.85
3nlwB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 3nm0A-3bxzA:
undetectable
3nm0B-3bxzA:
undetectable
3nm0A-3bxzA:
20.85
3nm0B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 3nnyA-3bxzA:
undetectable
3nnyB-3bxzA:
undetectable
3nnyA-3bxzA:
20.85
3nnyB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 9 ILE A 502
VAL A 465
THR A 559
ILE A 557
ILE A 438
None
1.21A 3p4wB-3bxzA:
undetectable
3p4wB-3bxzA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 10 ILE A 502
VAL A 465
THR A 559
ILE A 557
ILE A 438
None
1.23A 3p4wE-3bxzA:
undetectable
3p4wE-3bxzA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3q99A-3bxzA:
undetectable
3q99B-3bxzA:
undetectable
3q99A-3bxzA:
20.85
3q99B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 3q9aA-3bxzA:
undetectable
3q9aB-3bxzA:
undetectable
3q9aA-3bxzA:
20.85
3q9aB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.46A 3tylA-3bxzA:
undetectable
3tylB-3bxzA:
undetectable
3tylA-3bxzA:
20.85
3tylB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3tynA-3bxzA:
undetectable
3tynB-3bxzA:
undetectable
3tynA-3bxzA:
20.85
3tynB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 3tyoA-3bxzA:
undetectable
3tyoB-3bxzA:
undetectable
3tyoA-3bxzA:
20.85
3tyoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 3tyoA-3bxzA:
undetectable
3tyoB-3bxzA:
undetectable
3tyoA-3bxzA:
20.85
3tyoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3ufoA-3bxzA:
undetectable
3ufoB-3bxzA:
undetectable
3ufoA-3bxzA:
20.85
3ufoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3ufpA-3bxzA:
undetectable
3ufpB-3bxzA:
1.2
3ufpA-3bxzA:
20.85
3ufpB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 3ufrA-3bxzA:
undetectable
3ufrB-3bxzA:
undetectable
3ufrA-3bxzA:
20.85
3ufrB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3ufsA-3bxzA:
undetectable
3ufsB-3bxzA:
undetectable
3ufsA-3bxzA:
20.85
3ufsB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.45A 3uftA-3bxzA:
undetectable
3uftB-3bxzA:
undetectable
3uftA-3bxzA:
20.85
3uftB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 3ufvA-3bxzA:
undetectable
3ufvB-3bxzA:
undetectable
3ufvA-3bxzA:
20.85
3ufvB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 LEU A 423
SER A 583
GLU A 444
HIS A 555
None
1.02A 4aq7A-3bxzA:
2.1
4aq7A-3bxzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_D_LEUD902_0
(LEUCINE--TRNA LIGASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 9 LEU A 423
SER A 583
TYR A 587
GLU A 444
HIS A 555
None
1.31A 4aq7D-3bxzA:
0.0
4aq7D-3bxzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 LEU A 423
SER A 583
TYR A 587
HIS A 555
None
1.27A 4arcA-3bxzA:
undetectable
4arcA-3bxzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
6 / 12 ALA A 503
ILE A 557
ILE A 442
VAL A 500
HIS A 476
ILE A 474
None
1.43A 4ax8A-3bxzA:
3.3
4ax8A-3bxzA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.47A 4c39A-3bxzA:
undetectable
4c39B-3bxzA:
undetectable
4c39A-3bxzA:
20.85
4c39B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 4c39A-3bxzA:
undetectable
4c39B-3bxzA:
undetectable
4c39A-3bxzA:
20.85
4c39B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.50A 4canA-3bxzA:
undetectable
4canB-3bxzA:
undetectable
4canA-3bxzA:
20.85
4canB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 4ctuA-3bxzA:
undetectable
4ctuB-3bxzA:
0.2
4ctuA-3bxzA:
20.85
4ctuB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 4ctxA-3bxzA:
undetectable
4ctxB-3bxzA:
undetectable
4ctxA-3bxzA:
20.85
4ctxB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.44A 4d30A-3bxzA:
undetectable
4d30B-3bxzA:
undetectable
4d30A-3bxzA:
20.85
4d30B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.46A 4d31A-3bxzA:
undetectable
4d31B-3bxzA:
undetectable
4d31A-3bxzA:
20.85
4d31B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.45A 4d31A-3bxzA:
undetectable
4d31B-3bxzA:
undetectable
4d31A-3bxzA:
20.85
4d31B-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 6 ASN A 486
ALA A 488
THR A 511
LEU A 135
None
1.05A 4ejgD-3bxzA:
undetectable
4ejgD-3bxzA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 4euxA-3bxzA:
undetectable
4euxB-3bxzA:
1.2
4euxA-3bxzA:
20.85
4euxB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 4fvwA-3bxzA:
undetectable
4fvwB-3bxzA:
undetectable
4fvwA-3bxzA:
20.85
4fvwB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 4fvxA-3bxzA:
undetectable
4fvxB-3bxzA:
undetectable
4fvxA-3bxzA:
20.85
4fvxB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 4fvyA-3bxzA:
undetectable
4fvyB-3bxzA:
undetectable
4fvyA-3bxzA:
20.85
4fvyB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 4gqeA-3bxzA:
undetectable
4gqeB-3bxzA:
undetectable
4gqeA-3bxzA:
20.85
4gqeB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.44A 4imwA-3bxzA:
undetectable
4imwB-3bxzA:
undetectable
4imwA-3bxzA:
20.85
4imwB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 4k5fA-3bxzA:
undetectable
4k5fB-3bxzA:
undetectable
4k5fA-3bxzA:
20.85
4k5fB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 4kciA-3bxzA:
undetectable
4kciB-3bxzA:
undetectable
4kciA-3bxzA:
20.85
4kciB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 4kcjA-3bxzA:
undetectable
4kcjB-3bxzA:
undetectable
4kcjA-3bxzA:
20.85
4kcjB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 4kckA-3bxzA:
undetectable
4kckB-3bxzA:
undetectable
4kckA-3bxzA:
20.85
4kckB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 4kcmA-3bxzA:
undetectable
4kcmB-3bxzA:
undetectable
4kcmA-3bxzA:
20.85
4kcmB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 4kcoA-3bxzA:
undetectable
4kcoB-3bxzA:
undetectable
4kcoA-3bxzA:
20.85
4kcoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.47A 4luxA-3bxzA:
undetectable
4luxB-3bxzA:
undetectable
4luxA-3bxzA:
20.85
4luxB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 4luxA-3bxzA:
undetectable
4luxB-3bxzA:
undetectable
4luxA-3bxzA:
20.85
4luxB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 12 ALA A 120
GLY A 151
ALA A  67
VAL A  71
VAL A  70
None
1.05A 4nkxC-3bxzA:
undetectable
4nkxC-3bxzA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
5 / 12 ALA A 120
GLY A 151
ALA A  67
VAL A  71
VAL A  70
None
1.03A 4nkxD-3bxzA:
undetectable
4nkxD-3bxzA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 4 ALA A 398
VAL A 411
GLY A 392
THR A 391
None
1.11A 4ubeA-3bxzA:
undetectable
4ubeA-3bxzA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 8 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.42A 4uchA-3bxzA:
undetectable
4uchB-3bxzA:
undetectable
4uchA-3bxzA:
21.36
4uchB-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.47A 4uh5A-3bxzA:
undetectable
4uh5B-3bxzA:
undetectable
4uh5A-3bxzA:
21.36
4uh5B-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 4upoA-3bxzA:
undetectable
4upoB-3bxzA:
undetectable
4upoA-3bxzA:
20.85
4upoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 4v3vA-3bxzA:
undetectable
4v3vB-3bxzA:
undetectable
4v3vA-3bxzA:
20.85
4v3vB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 4v3xA-3bxzA:
undetectable
4v3xB-3bxzA:
undetectable
4v3xA-3bxzA:
20.85
4v3xB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5adcA-3bxzA:
undetectable
5adcB-3bxzA:
undetectable
5adcA-3bxzA:
20.85
5adcB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 5agkA-3bxzA:
undetectable
5agkB-3bxzA:
1.3
5agkA-3bxzA:
20.85
5agkB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5aglA-3bxzA:
undetectable
5aglB-3bxzA:
undetectable
5aglA-3bxzA:
20.85
5aglB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.46A 5agoA-3bxzA:
undetectable
5agoB-3bxzA:
undetectable
5agoA-3bxzA:
20.85
5agoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 5agpA-3bxzA:
undetectable
5agpB-3bxzA:
undetectable
5agpA-3bxzA:
20.85
5agpB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 5 GLN A 378
ILE A 404
ILE A 216
TYR A 405
None
1.29A 5dnuA-3bxzA:
undetectable
5dnuA-3bxzA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.45A 5fvqA-3bxzA:
undetectable
5fvqB-3bxzA:
undetectable
5fvqA-3bxzA:
20.85
5fvqB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 5fvsA-3bxzA:
undetectable
5fvsB-3bxzA:
undetectable
5fvsA-3bxzA:
20.85
5fvsB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5fvsA-3bxzA:
undetectable
5fvsB-3bxzA:
undetectable
5fvsA-3bxzA:
20.85
5fvsB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.48A 5fvvA-3bxzA:
undetectable
5fvvB-3bxzA:
0.8
5fvvA-3bxzA:
21.36
5fvvB-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5fvvA-3bxzA:
undetectable
5fvvB-3bxzA:
0.8
5fvvA-3bxzA:
21.36
5fvvB-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 5g0oA-3bxzA:
undetectable
5g0oB-3bxzA:
undetectable
5g0oA-3bxzA:
20.85
5g0oB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 8 GLN A 578
GLY A 107
THR A 111
ASN A 415
None
ADP  A 901 (-3.5A)
None
None
0.88A 5hwaA-3bxzA:
undetectable
5hwaA-3bxzA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
3 / 3 THR A 178
PRO A 222
ARG A 220
None
0.81A 5nd7B-3bxzA:
undetectable
5nd7B-3bxzA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.48A 5unwA-3bxzA:
undetectable
5unwB-3bxzA:
undetectable
5unwA-3bxzA:
20.85
5unwB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 5vukA-3bxzA:
undetectable
5vukB-3bxzA:
undetectable
5vukA-3bxzA:
20.85
5vukB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5vukA-3bxzA:
undetectable
5vukB-3bxzA:
undetectable
5vukA-3bxzA:
20.85
5vukB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5vunA-3bxzA:
undetectable
5vunB-3bxzA:
undetectable
5vunA-3bxzA:
20.85
5vunB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.48A 5vuoA-3bxzA:
undetectable
5vuoB-3bxzA:
undetectable
5vuoA-3bxzA:
20.85
5vuoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 5vuoA-3bxzA:
undetectable
5vuoB-3bxzA:
undetectable
5vuoA-3bxzA:
20.85
5vuoB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.48A 5vuqA-3bxzA:
undetectable
5vuqB-3bxzA:
undetectable
5vuqA-3bxzA:
20.85
5vuqB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5vuqA-3bxzA:
undetectable
5vuqB-3bxzA:
undetectable
5vuqA-3bxzA:
20.85
5vuqB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5vusA-3bxzA:
undetectable
5vusB-3bxzA:
undetectable
5vusA-3bxzA:
20.85
5vusB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.49A 5vutA-3bxzA:
undetectable
5vutB-3bxzA:
undetectable
5vutA-3bxzA:
20.85
5vutB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.48A 5vuuA-3bxzA:
undetectable
5vuuB-3bxzA:
undetectable
5vuuA-3bxzA:
20.85
5vuuB-3bxzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.45A 5vuwA-3bxzA:
undetectable
5vuwB-3bxzA:
undetectable
5vuwA-3bxzA:
21.36
5vuwB-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.45A 5vuyA-3bxzA:
1.3
5vuyB-3bxzA:
undetectable
5vuyA-3bxzA:
21.36
5vuyB-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.47A 5vuzA-3bxzA:
undetectable
5vuzB-3bxzA:
undetectable
5vuzA-3bxzA:
21.36
5vuzB-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.44A 5vv2A-3bxzA:
undetectable
5vv2B-3bxzA:
1.2
5vv2A-3bxzA:
21.36
5vv2B-3bxzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 6ausA-3bxzA:
undetectable
6ausB-3bxzA:
undetectable
6ausA-3bxzA:
11.94
6ausB-3bxzA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 6auvA-3bxzA:
undetectable
6auvB-3bxzA:
undetectable
6auvA-3bxzA:
11.94
6auvB-3bxzA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.50A 6auvA-3bxzA:
undetectable
6auvB-3bxzA:
undetectable
6auvA-3bxzA:
11.94
6auvB-3bxzA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.46A 6auwA-3bxzA:
undetectable
6auwB-3bxzA:
undetectable
6auwA-3bxzA:
11.94
6auwB-3bxzA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
None
1.45A 6auwA-3bxzA:
undetectable
6auwB-3bxzA:
undetectable
6auwA-3bxzA:
11.94
6auwB-3bxzA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.50A 6auyA-3bxzA:
undetectable
6auyB-3bxzA:
1.1
6auyA-3bxzA:
10.47
6auyB-3bxzA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 6av0A-3bxzA:
0.3
6av0B-3bxzA:
1.2
6av0A-3bxzA:
10.47
6av0B-3bxzA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.49A 6av3A-3bxzA:
undetectable
6av3B-3bxzA:
1.2
6av3A-3bxzA:
10.47
6av3B-3bxzA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli)
4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
None
1.47A 6av4A-3bxzA:
undetectable
6av4B-3bxzA:
undetectable
6av4A-3bxzA:
10.47
6av4B-3bxzA:
10.47