SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3byh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		3 / 3 VAL B 561
TRP B 555
TRP B 564
 None
 1.33A 1c4dA-3byhB:
undetectable
1c4dB-3byhB:
undetectable		 1c4dA-3byhB:
5.22
1c4dB-3byhB:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		5 / 12 LEU B 612
LEU B 553
LEU B 554
GLY B 547
LEU B 544
 None
 0.96A 1g50B-3byhB:
undetectable		 1g50B-3byhB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		5 / 11 LEU B 612
LEU B 553
LEU B 554
GLY B 547
LEU B 544
 None
 0.96A 1g50C-3byhB:
undetectable		 1g50C-3byhB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 7 LEU B 405
TYR B 398
MET B 608
ILE B 611
 None
 1.08A 1tuvA-3byhB:
undetectable		 1tuvA-3byhB:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		5 / 11 ASN B 524
ILE B 536
LEU B 544
THR B 613
PHE B 550
 None
 1.40A 1tw4A-3byhB:
undetectable		 1tw4A-3byhB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 8 ARG B 419
LEU B 425
VAL B 459
VAL B 479
 None
 1.02A 2bdmA-3byhB:
1.0		 2bdmA-3byhB:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 8 SER B 435
LEU B 428
PHE B 496
LEU B 493
 None
 0.74A 3i45A-3byhB:
undetectable		 3i45A-3byhB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		5 / 12 GLU B 395
VAL B 427
ASP B 417
ILE B 423
GLU B 426
 None
 1.35A 3jayA-3byhB:
undetectable		 3jayA-3byhB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		5 / 12 GLU B 395
VAL B 427
ASP B 417
ILE B 423
GLU B 426
 None
 1.37A 3jb3A-3byhB:
undetectable		 3jb3A-3byhB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		5 / 12 LEU B 612
LEU B 553
LEU B 554
GLY B 547
LEU B 544
 None
 1.01A 3olsA-3byhB:
undetectable		 3olsA-3byhB:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 7 PRO B 449
LYS B 447
ARG B 451
PRO B 445
 None
 1.16A 3ucbB-3byhB:
undetectable		 3ucbB-3byhB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 8 LEU B 424
VAL B 411
TYR B 398
LEU B 493
 None
 1.03A 3v81A-3byhB:
undetectable		 3v81A-3byhB:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B402_1
(PROTEASE)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 5 PRO B 449
LYS B 447
ARG B 451
PRO B 445
 None
 1.20A 4j5jB-3byhB:
undetectable		 4j5jB-3byhB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		5 / 12 ALA B 587
LEU B 553
ILE B 609
LEU B 544
ILE B 601
 None
 1.10A 4pstA-3byhB:
undetectable		 4pstA-3byhB:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 7 ARG B 525
THR B 613
ILE B 616
LEU B 553
 None
 0.85A 5te8A-3byhB:
undetectable		 5te8A-3byhB:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3byh FIMBRIN ABD2
(Homo
sapiens) 		4 / 8 ARG B 525
THR B 613
ILE B 616
LEU B 553
 None
 0.75A 5te8B-3byhB:
undetectable		 5te8B-3byhB:
17.23