SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3byv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		5 / 12 ALA A 548
LEU A 546
LEU A 404
ARG A 558
ILE A 497
 None
 1.21A 1errA-3byvA:
undetectable		 1errA-3byvA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 ASP A 541
THR A 551
PRO A 552
 None
 0.56A 2pynB-3byvA:
undetectable		 2pynB-3byvA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 ASP A 541
THR A 551
PRO A 552
 None
 0.59A 2qakB-3byvA:
undetectable		 2qakB-3byvA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		5 / 12 ALA A 548
LEU A 546
LEU A 404
ARG A 558
ILE A 497
 None
 1.12A 2qxsA-3byvA:
undetectable		 2qxsA-3byvA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		5 / 12 ALA A 548
LEU A 546
LEU A 404
ARG A 558
ILE A 497
 None
 1.09A 2qxsB-3byvA:
undetectable		 2qxsB-3byvA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 SER A 412
TYR A 416
HIS A 414
 None
 0.81A 2r2vD-3byvA:
undetectable		 2r2vD-3byvA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 GLU A 560
GLN A 525
ARG A 528
 None
 0.97A 2w3bB-3byvA:
undetectable		 2w3bB-3byvA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		5 / 12 LEU A 530
THR A 403
VAL A 493
GLY A 491
ILE A 407
 None
 1.23A 3bf1A-3byvA:
undetectable
3bf1B-3byvA:
undetectable		 3bf1A-3byvA:
20.81
3bf1B-3byvA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		4 / 4 LEU A 384
ALA A 225
PHE A 219
ASN A 376
 None
 1.32A 3vasA-3byvA:
undetectable		 3vasA-3byvA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 TYR A 422
ARG A 457
SER A 456
 None
 1.13A 4dr2I-3byvA:
undetectable
4dr2J-3byvA:
undetectable		 4dr2I-3byvA:
18.23
4dr2J-3byvA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 TYR A 422
ARG A 457
SER A 456
 None
 1.19A 4lf7I-3byvA:
undetectable
4lf7J-3byvA:
undetectable		 4lf7I-3byvA:
18.23
4lf7J-3byvA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 TYR A 422
ARG A 457
SER A 456
 None
 1.19A 4lf8I-3byvA:
undetectable
4lf8J-3byvA:
undetectable		 4lf8I-3byvA:
18.23
4lf8J-3byvA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 GLY A 209
PRO A 210
GLN A 401
 None
 0.45A 4oltB-3byvA:
undetectable		 4oltB-3byvA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 GLY A 209
PRO A 210
GLN A 405
 None
 0.38A 4oltB-3byvA:
undetectable		 4oltB-3byvA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 GLY A 209
PRO A 210
GLN A 401
 None
 0.37A 4qwpB-3byvA:
undetectable		 4qwpB-3byvA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 GLY A 209
PRO A 210
GLN A 405
 None
 0.52A 4qwpB-3byvA:
undetectable		 4qwpB-3byvA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		5 / 12 LEU A 410
VAL A 493
VAL A 429
TYR A 370
GLY A 440
 None
None
None
EDO  A 602 (-4.2A)
MG  A 601 ( 4.5A)
 1.44A 5i8fA-3byvA:
undetectable		 5i8fA-3byvA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		5 / 12 PHE A 380
LEU A 384
ALA A 398
ARG A 221
ILE A 222
 None
 1.08A 5ljeA-3byvA:
undetectable		 5ljeA-3byvA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		5 / 10 PHE A 219
ARG A 221
LEU A 218
ILE A 494
LEU A 490
 None
 1.16A 5oy01-3byvA:
undetectable
5oy07-3byvA:
undetectable		 5oy01-3byvA:
14.29
5oy07-3byvA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		4 / 5 GLY A 448
ARG A 450
ASP A 447
GLN A 547
 None
 1.37A 5ubbA-3byvA:
undetectable		 5ubbA-3byvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3byv RHOPTRY KINASE
(Toxoplasma
gondii) 		3 / 3 THR A 230
GLU A 293
ASN A 376
 None
EDO  A 602 (-3.9A)
None
 0.74A 6nj9K-3byvA:
undetectable		 6nj9K-3byvA:
21.58