SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3byw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CD2_A_FOLA307_0 (DIHYDROFOLATE REDUCTASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 12	ILE A 137 ALA A 188 LEU A 186 LEU A 109 ILE A 135	None	0.93A	1cd2A-3bywA: undetectable	1cd2A-3bywA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERR_A_RALA600_2 (ESTROGEN RECEPTOR)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 6	LEU A 100 LEU A 88 LEU A 83 LEU A 57	None	0.84A	1errA-3bywA: undetectable	1errA-3bywA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_C_TRPC81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.18A	1gtnB-3bywA: undetectable 1gtnC-3bywA: undetectable	1gtnB-3bywA: 22.45 1gtnC-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_I_TRPI81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.18A	1gtnH-3bywA: undetectable 1gtnI-3bywA: undetectable	1gtnH-3bywA: 22.45 1gtnI-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_J_TRPJ81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 8	ALA A 67 GLY A 86 ALA A 188 ILE A 169	None	0.74A	1gtnI-3bywA: undetectable 1gtnJ-3bywA: undetectable	1gtnI-3bywA: 22.45 1gtnJ-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RB3_B_MTXB161_1 (DIHYDROFOLATE REDUCTASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 12	ILE A 137 ALA A 188 SER A 73 LEU A 109 ILE A 135	None	0.97A	1rb3B-3bywA: undetectable	1rb3B-3bywA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_T_TRPT81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.19A	1utdT-3bywA: undetectable 1utdU-3bywA: undetectable	1utdT-3bywA: 22.45 1utdU-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CD2_A_FOLA307_0 (DIHYDROFOLATE REDUCTASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 12	ILE A 137 ALA A 188 LEU A 186 LEU A 109 ILE A 135	None	1.00A	2cd2A-3bywA: undetectable	2cd2A-3bywA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XKW_B_P1BB1475_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 6	LEU A 121 ILE A 135 ILE A 169 LEU A 83	None	0.90A	2xkwB-3bywA: undetectable	2xkwB-3bywA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DGQ_A_EAAA211_1 (GLUTATHIONE S-TRANSFERASE P)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 5	TYR A 60 ILE A 169 TYR A 170 THR A 171	None	1.42A	3dgqA-3bywA: undetectable	3dgqA-3bywA: 24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EIG_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 12	ILE A 137 ALA A 188 LEU A 186 SER A 73 LEU A 109	None	1.41A	3eigA-3bywA: undetectable	3eigA-3bywA: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UR0_B_SVRB516_1 (RNA-DEPENDENT RNA POLYMERASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 7	PRO A 70 GLY A 185 ALA A 184 ALA A 179 ASP A 180	None	1.43A	3ur0B-3bywA: undetectable	3ur0B-3bywA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UR0_C_SVRC516_1 (RNA-DEPENDENT RNA POLYMERASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 9	PRO A 70 GLY A 185 ALA A 184 ALA A 179 ASP A 180	None	1.39A	3ur0C-3bywA: undetectable	3ur0C-3bywA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NC3_A_ERMA1202_2 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 6	THR A 134 GLN A 81 LEU A 77 GLU A 174	None	1.21A	4nc3A-3bywA: undetectable	4nc3A-3bywA: 18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PWD_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 8	LEU A 121 VAL A 102 VAL A 74 LEU A 119	None	0.99A	4pwdA-3bywA: undetectable	4pwdA-3bywA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UYM_A_VORA590_1 (14-ALPHA STEROL DEMETHYLASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 7	ALA A 188 ILE A 166 LEU A 100 PHE A 65	None	1.08A	4uymA-3bywA: undetectable	4uymA-3bywA: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UYM_B_VORB590_1 (14-ALPHA STEROL DEMETHYLASE)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	4 / 7	ALA A 188 ILE A 166 LEU A 100 PHE A 65	None	1.07A	4uymB-3bywA: undetectable	4uymB-3bywA: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5eeuF-3bywA: undetectable 5eeuG-3bywA: undetectable	5eeuF-3bywA: 22.45 5eeuG-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.20A	5eeuO-3bywA: undetectable 5eeuP-3bywA: undetectable	5eeuO-3bywA: 22.45 5eeuP-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.19A	5eeuQ-3bywA: undetectable 5eeuR-3bywA: undetectable	5eeuQ-3bywA: 22.45 5eeuR-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5eevF-3bywA: undetectable 5eevG-3bywA: undetectable	5eevF-3bywA: 22.45 5eevG-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 12	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.16A	5eevI-3bywA: undetectable 5eevJ-3bywA: undetectable	5eevI-3bywA: 22.45 5eevJ-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.20A	5eevO-3bywA: undetectable 5eevP-3bywA: undetectable	5eevO-3bywA: 22.45 5eevP-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.19A	5eevQ-3bywA: undetectable 5eevR-3bywA: undetectable	5eevQ-3bywA: 22.45 5eevR-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5eewF-3bywA: undetectable 5eewG-3bywA: undetectable	5eewF-3bywA: 22.45 5eewG-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 12	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.16A	5eewI-3bywA: undetectable 5eewJ-3bywA: undetectable	5eewI-3bywA: 22.45 5eewJ-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.20A	5eewO-3bywA: undetectable 5eewP-3bywA: undetectable	5eewO-3bywA: 22.45 5eewP-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.19A	5eewQ-3bywA: undetectable 5eewR-3bywA: undetectable	5eewQ-3bywA: 22.45 5eewR-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEX_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5eexF-3bywA: undetectable 5eexG-3bywA: undetectable	5eexF-3bywA: 22.45 5eexG-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEX_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.20A	5eexO-3bywA: undetectable 5eexP-3bywA: undetectable	5eexO-3bywA: 22.45 5eexP-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEY_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5eeyF-3bywA: undetectable 5eeyG-3bywA: undetectable	5eeyF-3bywA: 22.45 5eeyG-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEY_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.21A	5eeyO-3bywA: undetectable 5eeyP-3bywA: undetectable	5eeyO-3bywA: 22.45 5eeyP-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5eezF-3bywA: undetectable 5eezG-3bywA: undetectable	5eezF-3bywA: 22.45 5eezG-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.21A	5eezO-3bywA: undetectable 5eezP-3bywA: undetectable	5eezO-3bywA: 22.45 5eezP-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF0_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5ef0F-3bywA: undetectable 5ef0G-3bywA: undetectable	5ef0F-3bywA: 22.45 5ef0G-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF0_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.20A	5ef0O-3bywA: undetectable 5ef0P-3bywA: undetectable	5ef0O-3bywA: 22.45 5ef0P-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.17A	5ef1F-3bywA: undetectable 5ef1G-3bywA: undetectable	5ef1F-3bywA: 22.45 5ef1G-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.20A	5ef1O-3bywA: undetectable 5ef1P-3bywA: undetectable	5ef1O-3bywA: 22.45 5ef1P-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.18A	5ef2F-3bywA: undetectable 5ef2G-3bywA: undetectable	5ef2F-3bywA: 22.45 5ef2G-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.21A	5ef2O-3bywA: undetectable 5ef2P-3bywA: undetectable	5ef2O-3bywA: 22.45 5ef2P-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	ALA A 67 GLY A 86 ALA A 188 THR A 87 ILE A 169	None	1.18A	5ef3F-3bywA: undetectable 5ef3G-3bywA: undetectable	5ef3F-3bywA: 22.45 5ef3G-3bywA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3byw	PUTATIVE ARABINOFURANOSYLTRAN SFERASE (Corynebacterium diphtheriae)	5 / 10	GLY A 86 ALA A 188 THR A 87 ILE A 169 ALA A 67	None	1.21A	5ef3O-3bywA: undetectable 5ef3P-3bywA: undetectable	5ef3O-3bywA: 22.45 5ef3P-3bywA: 22.45

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CD2_A_FOLA307_0","DIHYDROFOLATE REDUCTASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ILE A 137;ALA A 188;LEU A 186;LEU A 109;ILE A 135","None","0.93A","1cd2A-3bywA:undetectable","1cd2A-3bywA:20.66"],["1ERR_A_RALA600_2","ESTROGEN RECEPTOR","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"LEU A 100;LEU A  88;LEU A  83;LEU A  57","None","0.84A","1errA-3bywA:undetectable","1errA-3bywA:20.85"],["1GTN_C_TRPC81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.18A","1gtnB-3bywA:undetectable;1gtnC-3bywA:undetectable","1gtnB-3bywA:22.45;1gtnC-3bywA:22.45"],["1GTN_I_TRPI81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.18A","1gtnH-3bywA:undetectable;1gtnI-3bywA:undetectable","1gtnH-3bywA:22.45;1gtnI-3bywA:22.45"],["1GTN_J_TRPJ81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"ALA A  67;GLY A  86;ALA A 188;ILE A 169","None","0.74A","1gtnI-3bywA:undetectable;1gtnJ-3bywA:undetectable","1gtnI-3bywA:22.45;1gtnJ-3bywA:22.45"],["1RB3_B_MTXB161_1","DIHYDROFOLATE REDUCTASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ILE A 137;ALA A 188;SER A  73;LEU A 109;ILE A 135","None","0.97A","1rb3B-3bywA:undetectable","1rb3B-3bywA:22.91"],["1UTD_T_TRPT81_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.19A","1utdT-3bywA:undetectable;1utdU-3bywA:undetectable","1utdT-3bywA:22.45;1utdU-3bywA:22.45"],["2CD2_A_FOLA307_0","DIHYDROFOLATE REDUCTASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ILE A 137;ALA A 188;LEU A 186;LEU A 109;ILE A 135","None","1.00A","2cd2A-3bywA:undetectable","2cd2A-3bywA:20.66"],["2XKW_B_P1BB1475_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"LEU A 121;ILE A 135;ILE A 169;LEU A  83","None","0.90A","2xkwB-3bywA:undetectable","2xkwB-3bywA:20.73"],["3DGQ_A_EAAA211_1","GLUTATHIONE S-TRANSFERASE P","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"TYR A  60;ILE A 169;TYR A 170;THR A 171","None","1.42A","3dgqA-3bywA:undetectable","3dgqA-3bywA:24.65"],["3EIG_A_MTXA200_1","DIHYDROFOLATE REDUCTASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ILE A 137;ALA A 188;LEU A 186;SER A  73;LEU A 109","None","1.41A","3eigA-3bywA:undetectable","3eigA-3bywA:22.00"],["3UR0_B_SVRB516_1","RNA-DEPENDENT RNA POLYMERASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"PRO A  70;GLY A 185;ALA A 184;ALA A 179;ASP A 180","None","1.43A","3ur0B-3bywA:undetectable","3ur0B-3bywA:17.46"],["3UR0_C_SVRC516_1","RNA-DEPENDENT RNA POLYMERASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"PRO A  70;GLY A 185;ALA A 184;ALA A 179;ASP A 180","None","1.39A","3ur0C-3bywA:undetectable","3ur0C-3bywA:17.46"],["4NC3_A_ERMA1202_2","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"THR A 134;GLN A  81;LEU A  77;GLU A 174","None","1.21A","4nc3A-3bywA:undetectable","4nc3A-3bywA:18.37"],["4PWD_A_NVPA901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"LEU A 121;VAL A 102;VAL A  74;LEU A 119","None","0.99A","4pwdA-3bywA:undetectable","4pwdA-3bywA:15.61"],["4UYM_A_VORA590_1","14-ALPHA STEROL DEMETHYLASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"ALA A 188;ILE A 166;LEU A 100;PHE A  65","None","1.08A","4uymA-3bywA:undetectable","4uymA-3bywA:17.86"],["4UYM_B_VORB590_1","14-ALPHA STEROL DEMETHYLASE","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",4,"ALA A 188;ILE A 166;LEU A 100;PHE A  65","None","1.07A","4uymB-3bywA:undetectable","4uymB-3bywA:17.86"],["5EEU_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5eeuF-3bywA:undetectable;5eeuG-3bywA:undetectable","5eeuF-3bywA:22.45;5eeuG-3bywA:22.45"],["5EEU_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.20A","5eeuO-3bywA:undetectable;5eeuP-3bywA:undetectable","5eeuO-3bywA:22.45;5eeuP-3bywA:22.45"],["5EEU_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.19A","5eeuQ-3bywA:undetectable;5eeuR-3bywA:undetectable","5eeuQ-3bywA:22.45;5eeuR-3bywA:22.45"],["5EEV_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5eevF-3bywA:undetectable;5eevG-3bywA:undetectable","5eevF-3bywA:22.45;5eevG-3bywA:22.45"],["5EEV_I_TRPI101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.16A","5eevI-3bywA:undetectable;5eevJ-3bywA:undetectable","5eevI-3bywA:22.45;5eevJ-3bywA:22.45"],["5EEV_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.20A","5eevO-3bywA:undetectable;5eevP-3bywA:undetectable","5eevO-3bywA:22.45;5eevP-3bywA:22.45"],["5EEV_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.19A","5eevQ-3bywA:undetectable;5eevR-3bywA:undetectable","5eevQ-3bywA:22.45;5eevR-3bywA:22.45"],["5EEW_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5eewF-3bywA:undetectable;5eewG-3bywA:undetectable","5eewF-3bywA:22.45;5eewG-3bywA:22.45"],["5EEW_I_TRPI101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.16A","5eewI-3bywA:undetectable;5eewJ-3bywA:undetectable","5eewI-3bywA:22.45;5eewJ-3bywA:22.45"],["5EEW_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.20A","5eewO-3bywA:undetectable;5eewP-3bywA:undetectable","5eewO-3bywA:22.45;5eewP-3bywA:22.45"],["5EEW_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.19A","5eewQ-3bywA:undetectable;5eewR-3bywA:undetectable","5eewQ-3bywA:22.45;5eewR-3bywA:22.45"],["5EEX_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5eexF-3bywA:undetectable;5eexG-3bywA:undetectable","5eexF-3bywA:22.45;5eexG-3bywA:22.45"],["5EEX_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.20A","5eexO-3bywA:undetectable;5eexP-3bywA:undetectable","5eexO-3bywA:22.45;5eexP-3bywA:22.45"],["5EEY_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5eeyF-3bywA:undetectable;5eeyG-3bywA:undetectable","5eeyF-3bywA:22.45;5eeyG-3bywA:22.45"],["5EEY_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.21A","5eeyO-3bywA:undetectable;5eeyP-3bywA:undetectable","5eeyO-3bywA:22.45;5eeyP-3bywA:22.45"],["5EEZ_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5eezF-3bywA:undetectable;5eezG-3bywA:undetectable","5eezF-3bywA:22.45;5eezG-3bywA:22.45"],["5EEZ_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.21A","5eezO-3bywA:undetectable;5eezP-3bywA:undetectable","5eezO-3bywA:22.45;5eezP-3bywA:22.45"],["5EF0_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5ef0F-3bywA:undetectable;5ef0G-3bywA:undetectable","5ef0F-3bywA:22.45;5ef0G-3bywA:22.45"],["5EF0_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.20A","5ef0O-3bywA:undetectable;5ef0P-3bywA:undetectable","5ef0O-3bywA:22.45;5ef0P-3bywA:22.45"],["5EF1_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.17A","5ef1F-3bywA:undetectable;5ef1G-3bywA:undetectable","5ef1F-3bywA:22.45;5ef1G-3bywA:22.45"],["5EF1_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.20A","5ef1O-3bywA:undetectable;5ef1P-3bywA:undetectable","5ef1O-3bywA:22.45;5ef1P-3bywA:22.45"],["5EF2_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.18A","5ef2F-3bywA:undetectable;5ef2G-3bywA:undetectable","5ef2F-3bywA:22.45;5ef2G-3bywA:22.45"],["5EF2_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.21A","5ef2O-3bywA:undetectable;5ef2P-3bywA:undetectable","5ef2O-3bywA:22.45;5ef2P-3bywA:22.45"],["5EF3_F_TRPF101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"ALA A  67;GLY A  86;ALA A 188;THR A  87;ILE A 169","None","1.18A","5ef3F-3bywA:undetectable;5ef3G-3bywA:undetectable","5ef3F-3bywA:22.45;5ef3G-3bywA:22.45"],["5EF3_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3byw","PUTATIVE ARABINOFURANOSYLTRANSFERASE","Corynebacterium diphtheriae",5,"GLY A  86;ALA A 188;THR A  87;ILE A 169;ALA A  67","None","1.21A","5ef3O-3bywA:undetectable;5ef3P-3bywA:undetectable","5ef3O-3bywA:22.45;5ef3P-3bywA:22.45"]]