SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ASN A  20
LEU A  19
LEU A  81
VAL A  97
ILE A  26
 None
 1.20A 3jw5A-3bz6A:
undetectable		 3jw5A-3bz6A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 LEU A 116
GLY A 118
GLN A 120
MET A 132
ILE A 172
 None
 1.21A 4oktA-3bz6A:
undetectable		 4oktA-3bz6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ARG A 151
LEU A 148
VAL A 104
LEU A 153
LEU A 110
 None
 1.15A 4or0B-3bz6A:
undetectable		 4or0B-3bz6A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A 126
GLU A 124
LEU A 145
HIS A 133
 None
 1.22A 4xi3B-3bz6A:
undetectable		 4xi3B-3bz6A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A 172
LEU A  17
ARG A  25
LEU A  76
 None
 0.82A 5b1aA-3bz6A:
undetectable
5b1aJ-3bz6A:
undetectable		 5b1aA-3bz6A:
15.42
5b1aJ-3bz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A 172
LEU A  17
ARG A  25
LEU A  76
 None
 0.84A 5b3sA-3bz6A:
undetectable
5b3sJ-3bz6A:
undetectable		 5b3sA-3bz6A:
15.42
5b3sJ-3bz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.20A 5hm8A-3bz6A:
undetectable		 5hm8A-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.19A 5hm8B-3bz6A:
undetectable		 5hm8B-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.20A 5hm8C-3bz6A:
undetectable		 5hm8C-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.20A 5hm8D-3bz6A:
undetectable		 5hm8D-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.20A 5hm8E-3bz6A:
undetectable		 5hm8E-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.20A 5hm8F-3bz6A:
undetectable		 5hm8F-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.27A 5hm8G-3bz6A:
undetectable		 5hm8G-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLU A  77
GLU A  23
THR A  22
LEU A  48
 None
 1.19A 5hm8H-3bz6A:
undetectable		 5hm8H-3bz6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 LEU A  17
ILE A 172
GLY A 173
LEU A  81
LEU A  27
 None
 0.91A 5o96A-3bz6A:
undetectable
5o96B-3bz6A:
undetectable		 5o96A-3bz6A:
20.95
5o96B-3bz6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A 172
LEU A  17
ARG A  25
LEU A  76
 None
 0.99A 5xdqA-3bz6A:
undetectable
5xdqJ-3bz6A:
undetectable		 5xdqA-3bz6A:
15.42
5xdqJ-3bz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 ILE A 172
LEU A  17
ARG A  25
LEU A  76
 None
 0.86A 5zcoA-3bz6A:
undetectable
5zcoJ-3bz6A:
undetectable		 5zcoA-3bz6A:
15.42
5zcoJ-3bz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A 172
LEU A  17
ARG A  25
LEU A  76
 None
 0.83A 5zcpA-3bz6A:
undetectable
5zcpJ-3bz6A:
undetectable		 5zcpA-3bz6A:
15.42
5zcpJ-3bz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bz6 UPF0502 PROTEIN
PSPTO_2686
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A 172
LEU A  17
ARG A  25
LEU A  76
 None
 0.85A 5zcqA-3bz6A:
undetectable
5zcqJ-3bz6A:
undetectable		 5zcqA-3bz6A:
15.42
5zcqJ-3bz6A:
16.57