SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bze'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		3 / 3 TRP A 167
GLU A  63
TYR A  59
 None
 0.91A 2a3aA-3bzeA:
undetectable		 2a3aA-3bzeA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		3 / 3 GLN A 226
THR A 200
TRP A 244
 None
 1.14A 2rctA-3bzeA:
undetectable		 2rctA-3bzeA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		4 / 8 TYR A 123
TYR A  84
TYR A 118
HIS A  93
 None
 0.98A 2zm8A-3bzeA:
undetectable		 2zm8A-3bzeA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		4 / 8 TYR A 123
TYR A  84
TYR A 118
HIS A  93
 None
 1.05A 2zmaA-3bzeA:
undetectable		 2zmaA-3bzeA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		3 / 3 TYR A 171
TYR A   7
GLU A 166
 None
 0.71A 3pfgA-3bzeA:
undetectable		 3pfgA-3bzeA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		5 / 12 THR A 187
LEU A 206
ALA A 205
GLY A 265
LEU A 266
 None
 1.04A 4xi3C-3bzeA:
undetectable		 4xi3C-3bzeA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		4 / 4 GLU A 232
THR A 233
GLU A 212
HIS A   3
 None
 1.21A 5utuF-3bzeA:
0.0		 5utuF-3bzeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3bze HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHA CHAIN
E
(Homo
sapiens) 		4 / 5 ALA A 135
TYR A 123
GLN A 141
ILE A 142
 None
 1.27A 6f6sA-3bzeA:
undetectable
6f6sB-3bzeA:
undetectable		 6f6sA-3bzeA:
14.72
6f6sB-3bzeA:
13.67