SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		5 / 11 ILE A 145
LEU A 132
LEU A 149
ILE A 152
PRO A 111
 None
 1.02A 3a50B-3bzhA:
undetectable		 3a50B-3bzhA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		4 / 8 ASN A  75
LEU A  45
ALA A  49
SER A  48
 None
 0.93A 3kp6A-3bzhA:
undetectable		 3kp6A-3bzhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		5 / 12 ILE A 145
LEU A 132
LEU A 149
ILE A 152
PRO A 111
 None
 0.98A 3vrmA-3bzhA:
undetectable		 3vrmA-3bzhA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		5 / 11 ILE A 152
ILE A 145
ILE A  83
ALA A  69
VAL A 113
 None
None
None
None
GOL  A 200 ( 4.3A)
 0.94A 4h1nA-3bzhA:
undetectable		 4h1nA-3bzhA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		4 / 6 LYS A 147
LEU A 150
PRO A  64
ARG A  51
 None
 1.37A 4yv5B-3bzhA:
undetectable		 4yv5B-3bzhA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		4 / 6 LYS A 147
LEU A 150
PRO A  64
ARG A  51
 None
 1.44A 4yv5A-3bzhA:
undetectable		 4yv5A-3bzhA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		4 / 5 LEU A  98
LEU A 135
PHE A 115
LEU A 155
 None
GOL  A 200 (-3.0A)
None
None
 1.05A 5gtrA-3bzhA:
undetectable		 5gtrA-3bzhA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		3 / 3 ILE A 130
VAL A 113
PRO A 111
 GOL  A 200 (-3.7A)
GOL  A 200 ( 4.3A)
None
 0.70A 5uunA-3bzhA:
undetectable		 5uunA-3bzhA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		5 / 10 LEU A 155
GLY A  85
ILE A  83
ILE A 130
ILE A 124
 None
None
None
GOL  A 200 (-3.7A)
None
 1.09A 6ebpD-3bzhA:
undetectable		 6ebpD-3bzhA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1
(Homo
sapiens) 		5 / 10 SER A  81
GLY A  70
ILE A 100
ILE A 152
ILE A  83
 None
 1.11A 6ebpD-3bzhA:
undetectable		 6ebpD-3bzhA:
19.08