SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 3c01 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS
SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS
(Salmonella
enterica;
Salmonella
enterica) 		5 / 12 ILE E 266
VAL E 329
VAL A 256
ALA A 257
LEU E 311
 None
 1.03A 1vptA-3c01E:
undetectable		 1vptA-3c01E:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3c01 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS
(Salmonella
enterica) 		4 / 7 VAL E 321
ILE E 278
ILE E 264
THR E 314
 None
 0.82A 3deuA-3c01E:
undetectable		 3deuA-3c01E:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 3c01 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS
(Salmonella
enterica) 		4 / 7 ARG E 286
VAL E 299
VAL A 245
VAL E 280
 None
 0.82A 3ufnB-3c01E:
undetectable		 3ufnB-3c01E:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3c01 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS
(Salmonella
enterica) 		4 / 8 LEU E 307
LEU E 332
VAL E 329
ILE E 266
 None
 0.95A 4oj4A-3c01E:
undetectable		 4oj4A-3c01E:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3c01 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS
SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS
(Salmonella
enterica;
Salmonella
enterica) 		5 / 12 ILE E 278
LEU E 307
ALA E 308
LEU A 254
THR E 314
 None
 0.97A 4psyA-3c01E:
undetectable		 4psyA-3c01E:
21.47