SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3c0d PUTATIVE NITRITE
REDUCTASE NADPH
(SMALL SUBUNIT)
OXIDOREDUCTASE
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 GLY A  50
PRO A  48
ASP A  88
ALA A  90
 None
 1.00A 1gxsA-3c0dA:
undetectable
1gxsB-3c0dA:
undetectable		 1gxsA-3c0dA:
17.34
1gxsB-3c0dA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QYX_A_ASDA500_1
(ESTRADIOL 17
BETA-DEHYDROGENASE 1)		 3c0d PUTATIVE NITRITE
REDUCTASE NADPH
(SMALL SUBUNIT)
OXIDOREDUCTASE
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 9 VAL A  60
LEU A  80
SER A  38
PHE A  18
VAL A  40
 None
 1.48A 1qyxA-3c0dA:
0.0		 1qyxA-3c0dA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 3c0d PUTATIVE NITRITE
REDUCTASE NADPH
(SMALL SUBUNIT)
OXIDOREDUCTASE
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 6 TYR A  34
ASN A 103
LEU A  12
ASP A  13
 None
 1.43A 3lslG-3c0dA:
undetectable		 3lslG-3c0dA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3c0d PUTATIVE NITRITE
REDUCTASE NADPH
(SMALL SUBUNIT)
OXIDOREDUCTASE
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 CYH A  10
LEU A  15
THR A  95
VAL A  23
ILE A  25
 None
 1.17A 4x1kD-3c0dA:
undetectable		 4x1kD-3c0dA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3c0d PUTATIVE NITRITE
REDUCTASE NADPH
(SMALL SUBUNIT)
OXIDOREDUCTASE
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 5 ILE A  59
PHE A  33
SER A  56
ALA A  70
 None
 1.19A 5msdA-3c0dA:
undetectable		 5msdA-3c0dA:
7.79