SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 7 ASP A 278
ASP A 279
TYR A 287
ARG A 290
 None
 1.47A 1cebA-3c0kA:
undetectable		 1cebA-3c0kA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 7 ASP A 278
ASP A 279
TYR A 287
ARG A 290
 None
 1.43A 1cebB-3c0kA:
undetectable		 1cebB-3c0kA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 6 ASN A 226
PHE A 234
ALA A 235
GLY A 232
 None
 1.12A 1l5qB-3c0kA:
3.1		 1l5qB-3c0kA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 TYR A 382
GLY A 111
VAL A  65
ALA A 106
PHE A  68
 None
 1.12A 1nw3A-3c0kA:
11.2		 1nw3A-3c0kA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 8 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 0.90A 1pk7B-3c0kA:
undetectable		 1pk7B-3c0kA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 1.02A 1pk9C-3c0kA:
undetectable		 1pk9C-3c0kA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 9 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 0.98A 1pw7B-3c0kA:
undetectable		 1pw7B-3c0kA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 8 GLY A 242
GLY A 241
MET A 240
LEU A 239
 None
 0.64A 1qzzA-3c0kA:
15.0		 1qzzA-3c0kA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 10 LEU A 336
ALA A 214
VAL A 296
GLN A 208
PHE A 338
 None
 1.33A 1rlbE-3c0kA:
undetectable		 1rlbE-3c0kA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 ALA A 373
LEU A 206
LEU A  93
LEU A  99
SER A 101
 None
 1.17A 1tz8A-3c0kA:
undetectable
1tz8B-3c0kA:
undetectable		 1tz8A-3c0kA:
17.49
1tz8B-3c0kA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 LEU A  93
LEU A  99
SER A 101
ALA A 373
LEU A 206
 None
 1.18A 1tz8A-3c0kA:
undetectable
1tz8B-3c0kA:
undetectable		 1tz8A-3c0kA:
17.49
1tz8B-3c0kA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 0.99A 1vhwA-3c0kA:
undetectable
1vhwD-3c0kA:
undetectable		 1vhwA-3c0kA:
21.62
1vhwD-3c0kA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 1.00A 1vhwC-3c0kA:
undetectable
1vhwE-3c0kA:
undetectable		 1vhwC-3c0kA:
21.62
1vhwE-3c0kA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 0.99A 1vhwA-3c0kA:
undetectable
1vhwD-3c0kA:
undetectable		 1vhwA-3c0kA:
21.62
1vhwD-3c0kA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 1.00A 1vhwC-3c0kA:
undetectable
1vhwE-3c0kA:
undetectable		 1vhwC-3c0kA:
21.62
1vhwE-3c0kA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 7 ARG A 103
LEU A 206
PRO A 180
VAL A 194
 None
 1.28A 2hrcA-3c0kA:
undetectable		 2hrcA-3c0kA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 5 SER A 109
LEU A 386
GLY A 385
ARG A 371
 None
 0.84A 2j2pA-3c0kA:
undetectable
2j2pB-3c0kA:
undetectable		 2j2pA-3c0kA:
20.40
2j2pB-3c0kA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 6 ARG A 371
SER A 109
LEU A 386
GLY A 385
 None
 0.94A 2j2pA-3c0kA:
undetectable
2j2pC-3c0kA:
undetectable		 2j2pA-3c0kA:
20.40
2j2pC-3c0kA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 6 ARG A 371
SER A 109
LEU A 386
GLY A 385
 None
 0.94A 2j2pD-3c0kA:
undetectable
2j2pF-3c0kA:
undetectable		 2j2pD-3c0kA:
20.40
2j2pF-3c0kA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 LEU A 183
VAL A 174
LEU A 128
SER A 157
ILE A 115
 None
 1.01A 3frqB-3c0kA:
undetectable		 3frqB-3c0kA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 8 LEU A 284
LEU A 225
CYH A 227
SER A 229
 None
 0.97A 3lm8A-3c0kA:
2.4
3lm8C-3c0kA:
2.4		 3lm8A-3c0kA:
18.00
3lm8C-3c0kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 5 VAL A 395
VAL A 364
ARG A 362
LYS A 319
 None
 1.27A 3rv5A-3c0kA:
undetectable
3rv5B-3c0kA:
undetectable		 3rv5A-3c0kA:
14.16
3rv5B-3c0kA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 11 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 1.00A 3uawA-3c0kA:
undetectable		 3uawA-3c0kA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 10 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 0.99A 3uayA-3c0kA:
undetectable		 3uayA-3c0kA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 LEU A 126
ILE A 117
HIS A 376
LEU A 112
GLY A 107
 None
 0.99A 3uwlB-3c0kA:
undetectable		 3uwlB-3c0kA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 8 ARG A 209
VAL A 125
ASP A 207
ARG A 212
 None
 1.11A 3uy4A-3c0kA:
2.6		 3uy4A-3c0kA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA802_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 9 PHE A 228
TYR A 230
ASP A 250
SER A 252
ASP A 279
 None
 0.42A 3v8vA-3c0kA:
27.5		 3v8vA-3c0kA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB802_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 ARG A 212
PHE A 228
TYR A 230
ASP A 279
ASP A 300
 None
 1.05A 3v8vB-3c0kA:
27.3		 3v8vB-3c0kA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB802_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 ARG A 212
PHE A 228
TYR A 230
SER A 252
ASP A 279
 None
 0.45A 3v8vB-3c0kA:
27.3		 3v8vB-3c0kA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		3 / 3 ARG A 212
ASP A 118
GLN A 127
 None
 0.83A 4azsA-3c0kA:
13.6		 4azsA-3c0kA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 8 LEU A 283
VAL A 276
VAL A 247
GLN A 245
 None
 0.92A 4em2A-3c0kA:
undetectable		 4em2A-3c0kA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 LEU A 124
GLN A  87
LEU A  83
THR A 202
PHE A 120
 None
 1.45A 4p6xI-3c0kA:
undetectable		 4p6xI-3c0kA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		3 / 3 GLU A 292
ARG A 290
GLN A 245
 None
 0.71A 4rtbA-3c0kA:
undetectable		 4rtbA-3c0kA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 7 ILE A 353
LEU A 335
GLY A 390
LYS A 389
 None
 1.04A 4z69A-3c0kA:
undetectable		 4z69A-3c0kA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 9 LEU A 128
LEU A 144
ILE A 153
SER A 142
ALA A 138
 None
 1.48A 4z69A-3c0kA:
undetectable		 4z69A-3c0kA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 TYR A 204
LEU A 206
ILE A 196
GLY A 121
HIS A 188
 None
 1.09A 5fsaA-3c0kA:
undetectable		 5fsaA-3c0kA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 9 ARG A 212
GLY A 203
VAL A 194
GLU A 187
ILE A 196
 None
 1.00A 5i3cA-3c0kA:
undetectable		 5i3cA-3c0kA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 6 TYR A 387
ASP A 375
HIS A 376
ILE A 105
 None
 1.29A 5ih0A-3c0kA:
undetectable		 5ih0A-3c0kA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 ALA A 325
LEU A 328
PHE A 294
LEU A 336
THR A 337
 None
 0.96A 5k9dA-3c0kA:
undetectable		 5k9dA-3c0kA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 LEU A 324
GLY A 317
ILE A 326
GLN A 327
ALA A 356
 None
 0.97A 5l0zA-3c0kA:
2.3		 5l0zA-3c0kA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 GLU A 165
LEU A 140
ALA A 133
ARG A 156
ARG A  64
 None
 1.26A 5nd4B-3c0kA:
undetectable		 5nd4B-3c0kA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 8 ASN A 322
GLN A 327
ILE A 326
GLY A 361
 None
 0.89A 5nzxA-3c0kA:
undetectable		 5nzxA-3c0kA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 7 ASN A 322
GLN A 327
ILE A 326
GLY A 361
 None
 0.92A 5nzyA-3c0kA:
2.0		 5nzyA-3c0kA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 GLN A 327
ALA A 360
LEU A 328
ILE A 297
CYH A 393
 None
 1.35A 5vlmB-3c0kA:
undetectable		 5vlmB-3c0kA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 6 TYR A 204
ILE A 185
GLU A 187
ARG A 209
 None
 0.97A 5z3jA-3c0kA:
undetectable		 5z3jA-3c0kA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		3 / 3 ARG A  52
ILE A  74
SER A  73
 None
 0.81A 5zw2A-3c0kA:
undetectable		 5zw2A-3c0kA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		4 / 6 ARG A  81
ARG A  82
LEU A  83
GLN A  85
 None
 0.61A 6b89B-3c0kA:
undetectable		 6b89B-3c0kA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		3 / 3 ALA A 214
PHE A 234
GLN A 208
 None
 0.83A 6eceA-3c0kA:
2.4		 6eceA-3c0kA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FZB_B_SRYB301_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 3c0k UPF0064 PROTEIN YCCW
(Escherichia
coli) 		5 / 12 GLU A 134
ASP A 155
LEU A 124
ILE A 105
THR A 116
 None
 1.46A 6fzbB-3c0kA:
undetectable		 6fzbB-3c0kA:
14.75