SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 138
GLY A 128
ILE A 184
SER A 185
ILE A 202
 None
 1.04A 3frqB-3c0rA:
undetectable		 3frqB-3c0rA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 255
SER A 225
LEU A 226
THR A 259
 None
 1.25A 4an2A-3c0rA:
undetectable		 4an2A-3c0rA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 179
ILE A 169
SER A 174
LEU A 158
 None
 0.80A 5fukA-3c0rA:
undetectable
5fukB-3c0rA:
undetectable		 5fukA-3c0rA:
21.54
5fukB-3c0rA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 142
VAL A 146
TYR A 165
GLN A 167
 None
 1.31A 5qggA-3c0rA:
undetectable		 5qggA-3c0rA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 142
VAL A 146
TYR A 165
GLN A 167
 None
 1.35A 5qgoA-3c0rA:
undetectable		 5qgoA-3c0rA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 142
VAL A 146
TYR A 165
GLN A 167
 None
 1.33A 5qgpA-3c0rA:
undetectable		 5qgpA-3c0rA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 142
VAL A 146
TYR A 165
GLN A 167
 None
 1.31A 5qgqA-3c0rA:
undetectable		 5qgqA-3c0rA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 142
VAL A 146
TYR A 165
GLN A 167
 None
 1.35A 5qhbA-3c0rA:
undetectable		 5qhbA-3c0rA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 138
GLY A 182
ILE A 192
PHE A 130
ILE A 129
 None
 0.90A 6ebzA-3c0rA:
undetectable		 6ebzA-3c0rA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 138
GLY A 182
ILE A 192
PHE A 130
ILE A 129
 None
 0.92A 6ebzB-3c0rA:
undetectable		 6ebzB-3c0rA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 138
GLY A 182
ILE A 192
PHE A 130
ILE A 129
 None
 0.92A 6ebzC-3c0rA:
undetectable		 6ebzC-3c0rA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 138
GLY A 182
ILE A 192
PHE A 130
ILE A 129
 None
 0.91A 6ebzD-3c0rA:
undetectable		 6ebzD-3c0rA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 138
GLY A 182
ILE A 192
PHE A 130
ILE A 129
 None
 0.90A 6gp2A-3c0rA:
undetectable		 6gp2A-3c0rA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3c0r UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 138
GLY A 182
ILE A 192
PHE A 130
ILE A 129
 None
 0.97A 6gp2B-3c0rA:
undetectable		 6gp2B-3c0rA:
21.31