SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3c0u UNCHARACTERIZED
PROTEIN YAEQ
(Escherichia
coli) 		3 / 3 ALA A 100
VAL A 102
TRP A  81
 None
 1.00A 1c4dA-3c0uA:
undetectable
1c4dB-3c0uA:
undetectable		 1c4dA-3c0uA:
7.22
1c4dB-3c0uA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3c0u UNCHARACTERIZED
PROTEIN YAEQ
(Escherichia
coli) 		3 / 3 TRP A  81
ALA A 100
VAL A 102
 None
 0.79A 1c4dA-3c0uA:
undetectable
1c4dB-3c0uA:
undetectable		 1c4dA-3c0uA:
7.22
1c4dB-3c0uA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3c0u UNCHARACTERIZED
PROTEIN YAEQ
(Escherichia
coli) 		4 / 7 LEU A 163
ALA A 154
VAL A  14
VAL A  12
 None
 0.81A 1epbA-3c0uA:
undetectable		 1epbA-3c0uA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3c0u UNCHARACTERIZED
PROTEIN YAEQ
(Escherichia
coli) 		3 / 3 GLU A  66
GLU A  68
LEU A  55
 None
 0.73A 1v8bA-3c0uA:
undetectable		 1v8bA-3c0uA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3c0u UNCHARACTERIZED
PROTEIN YAEQ
(Escherichia
coli) 		3 / 3 ASN A 169
MET A 150
PHE A 145
 None
 1.15A 3g4lD-3c0uA:
undetectable		 3g4lD-3c0uA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3c0u UNCHARACTERIZED
PROTEIN YAEQ
(Escherichia
coli) 		4 / 5 TYR A  50
TRP A  47
LEU A  42
LEU A 104
 None
 1.35A 5eshA-3c0uA:
undetectable		 5eshA-3c0uA:
15.50