SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c10'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 11 PRO A 542
HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
LEU A 810
 TSN  A 301 ( 4.5A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 (-4.2A)
 0.76A 1c3sA-3c10A:
39.2		 1c3sA-3c10A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 4 VAL A 663
TRP A 640
TRP A 552
 None
 1.30A 1gmkA-3c10A:
undetectable
1gmkB-3c10A:
undetectable		 1gmkA-3c10A:
7.64
1gmkB-3c10A:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 4 VAL A 663
TRP A 640
TRP A 552
 None
 1.18A 1gmkC-3c10A:
undetectable
1gmkD-3c10A:
undetectable		 1gmkC-3c10A:
7.64
1gmkD-3c10A:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 9 GLY A 678
PRO A 542
GLY A 841
GLY A 842
ASP A 801
 TSN  A 301 ( 3.7A)
TSN  A 301 ( 4.5A)
TSN  A 301 ( 3.9A)
None
ZN  A 101 ( 2.5A)
 1.10A 1mxdA-3c10A:
undetectable		 1mxdA-3c10A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 11 GLY A 678
PRO A 542
GLY A 841
GLY A 842
ASP A 801
 TSN  A 301 ( 3.7A)
TSN  A 301 ( 4.5A)
TSN  A 301 ( 3.9A)
None
ZN  A 101 ( 2.5A)
 1.08A 1mxgA-3c10A:
undetectable		 1mxgA-3c10A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 12 ASP A 626
GLY A 678
PHE A 679
HIS A 709
PHE A 738
ASP A 707
 TSN  A 301 ( 4.0A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 (-2.1A)
 1.28A 1t69A-3c10A:
39.9		 1t69A-3c10A:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 ASP A 626
HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
 TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
 0.53A 1t69A-3c10A:
39.9		 1t69A-3c10A:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 1v54A-3c10A:
undetectable		 1v54A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 1v54N-3c10A:
undetectable		 1v54N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 1v55A-3c10A:
undetectable		 1v55A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 1v55N-3c10A:
undetectable		 1v55N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 LEU A 884
LEU A 878
MET A 769
 None
 0.69A 1ya3B-3c10A:
undetectable		 1ya3B-3c10A:
19.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 11 HIS A 669
HIS A 670
ASP A 707
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 ( 2.5A)
None
 1.14A 1zz1A-3c10A:
47.9		 1zz1A-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		8 / 11 HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.48A 1zz1A-3c10A:
47.9		 1zz1A-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 11 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.17A 1zz1A-3c10A:
47.9		 1zz1A-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 669
HIS A 670
ASP A 707
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 ( 2.5A)
None
 1.16A 1zz1B-3c10A:
48.3
1zz1C-3c10A:
48.1		 1zz1B-3c10A:
33.57
1zz1C-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		8 / 12 HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.41A 1zz1B-3c10A:
48.3
1zz1C-3c10A:
48.1		 1zz1B-3c10A:
33.57
1zz1C-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.19A 1zz1B-3c10A:
48.3
1zz1C-3c10A:
48.1		 1zz1B-3c10A:
33.57
1zz1C-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 ASP A 624
HIS A 669
HIS A 670
GLY A 678
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 None
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.71A 1zz1C-3c10A:
48.1		 1zz1C-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 ASP A 624
HIS A 709
GLY A 678
ASP A 801
GLY A 841
 None
ZN  A 101 (-3.1A)
TSN  A 301 ( 3.7A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 1.12A 1zz1C-3c10A:
48.1		 1zz1C-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 669
HIS A 670
ASP A 707
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 ( 2.5A)
None
 1.14A 1zz1C-3c10A:
48.1		 1zz1C-3c10A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		7 / 9 HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
 0.43A 1zz1D-3c10A:
48.0		 1zz1D-3c10A:
33.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 2dyrA-3c10A:
undetectable		 2dyrA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 2dyrN-3c10A:
undetectable		 2dyrN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.75A 2dysA-3c10A:
undetectable		 2dysA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 2dysN-3c10A:
undetectable		 2dysN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 2eijA-3c10A:
undetectable		 2eijA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 2eijN-3c10A:
undetectable		 2eijN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 2eikA-3c10A:
undetectable		 2eikA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 2eikN-3c10A:
undetectable		 2eikN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 2eilA-3c10A:
undetectable		 2eilA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 2eilN-3c10A:
undetectable		 2eilN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.70A 2eimA-3c10A:
undetectable		 2eimA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 ILE A 888
ALA A 886
ALA A 880
LEU A 884
HIS A 730
 None
 0.99A 2h79A-3c10A:
undetectable		 2h79A-3c10A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 2y69A-3c10A:
undetectable		 2y69A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.67A 2y69N-3c10A:
undetectable		 2y69N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 2zxwA-3c10A:
undetectable		 2zxwA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.69A 2zxwN-3c10A:
undetectable		 2zxwN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 MET A 528
GLU A 543
ASP A 801
 None
None
ZN  A 101 ( 2.5A)
 1.10A 3a25A-3c10A:
3.4		 3a25A-3c10A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 3ablA-3c10A:
undetectable		 3ablA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.74A 3ablN-3c10A:
undetectable		 3ablN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.75A 3abmA-3c10A:
undetectable		 3abmA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.67A 3abmN-3c10A:
undetectable		 3abmN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.70A 3ag1N-3c10A:
undetectable		 3ag1N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.74A 3ag4N-3c10A:
undetectable		 3ag4N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 3asnA-3c10A:
undetectable		 3asnA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 3asnN-3c10A:
undetectable		 3asnN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 3asoA-3c10A:
undetectable		 3asoA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 3asoN-3c10A:
undetectable		 3asoN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 806
GLU A 804
HIS A 814
 None
 0.66A 3ba0A-3c10A:
undetectable		 3ba0A-3c10A:
19.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 5 HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
 0.08A 3c0zA-3c10A:
73.3		 3c0zA-3c10A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 8 HIS A 669
HIS A 670
ASP A 707
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 ( 2.5A)
None
 1.27A 3c0zB-3c10A:
67.2		 3c0zB-3c10A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		8 / 8 HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.14A 3c0zB-3c10A:
67.2		 3c0zB-3c10A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 8 PHE A 679
ASP A 801
HIS A 709
PHE A 738
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 ( 2.5A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
None
 1.43A 3c0zB-3c10A:
67.2		 3c0zB-3c10A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 8 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.17A 3c0zB-3c10A:
67.2		 3c0zB-3c10A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		4 / 8 PHE A 738
ASP A 801
PHE A 679
ASP A 707
 TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
 0.79A 3c0zB-3c10A:
67.2		 3c0zB-3c10A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 6 ASP A 626
HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
 TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
 0.23A 3c0zC-3c10A:
66.6		 3c0zC-3c10A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 ILE A 551
ALA A 851
LEU A 837
ALA A 838
LEU A 522
 None
 1.11A 3dauA-3c10A:
undetectable		 3dauA-3c10A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 3dtuA-3c10A:
undetectable		 3dtuA-3c10A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 3dtuC-3c10A:
undetectable		 3dtuC-3c10A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 9 MET A 783
PRO A 791
SER A 790
VAL A 835
GLY A 833
 None
 1.31A 3hcoA-3c10A:
1.9		 3hcoA-3c10A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 GLY A 713
GLU A 840
ALA A 838
ASP A 801
GLY A 799
 None
None
None
ZN  A 101 ( 2.5A)
None
 1.42A 3jzjA-3c10A:
undetectable		 3jzjA-3c10A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		4 / 7 GLU A 840
VAL A 796
VAL A 645
ALA A 662
 None
 1.06A 3kp6B-3c10A:
undetectable		 3kp6B-3c10A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 806
GLY A 811
GLY A 799
ALA A 847
SER A 550
 None
 1.12A 3sudB-3c10A:
undetectable		 3sudB-3c10A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 806
GLY A 811
GLY A 799
ALA A 847
SER A 550
 None
 1.15A 3sueD-3c10A:
undetectable		 3sueD-3c10A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 806
GLY A 811
GLY A 841
ALA A 847
SER A 550
 None
None
TSN  A 301 ( 3.9A)
None
None
 1.30A 3sueD-3c10A:
undetectable		 3sueD-3c10A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.69A 3wg7A-3c10A:
undetectable		 3wg7A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 3wg7N-3c10A:
undetectable		 3wg7N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.66A 3x2qN-3c10A:
undetectable		 3x2qN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 10 HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.29A 4bz6A-3c10A:
39.1		 4bz6A-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 10 HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.27A 4bz6A-3c10A:
39.1		 4bz6A-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 10 HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
PRO A 807
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 0.80A 4bz6A-3c10A:
39.1		 4bz6A-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.01A 4bz6A-3c10A:
39.1
4bz6B-3c10A:
39.0		 4bz6A-3c10A:
25.40
4bz6B-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 ASP A 707
HIS A 709
PHE A 738
PRO A 807
GLY A 842
 ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
None
None
 1.02A 4bz6A-3c10A:
39.1
4bz6B-3c10A:
39.0		 4bz6A-3c10A:
25.40
4bz6B-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		7 / 12 HIS A 669
HIS A 670
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.31A 4bz6A-3c10A:
39.1
4bz6B-3c10A:
39.0		 4bz6A-3c10A:
25.40
4bz6B-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 12 HIS A 669
HIS A 670
ASP A 707
HIS A 709
PHE A 738
PRO A 807
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
None
 0.79A 4bz6A-3c10A:
39.1
4bz6B-3c10A:
39.0		 4bz6A-3c10A:
25.40
4bz6B-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 669
HIS A 670
HIS A 709
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.22A 4bz6A-3c10A:
39.1
4bz6B-3c10A:
39.0		 4bz6A-3c10A:
25.40
4bz6B-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 12 ASP A 707
HIS A 709
PHE A 738
ASP A 801
PRO A 807
GLY A 842
 ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
None
 1.07A 4bz6C-3c10A:
39.3		 4bz6C-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		8 / 12 HIS A 669
HIS A 670
GLY A 678
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.34A 4bz6C-3c10A:
39.3		 4bz6C-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		8 / 12 HIS A 669
HIS A 670
GLY A 678
ASP A 707
HIS A 709
PHE A 738
ASP A 801
PRO A 807
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 0.85A 4bz6C-3c10A:
39.3		 4bz6C-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 12 HIS A 669
HIS A 670
GLY A 678
ASP A 707
HIS A 709
PRO A 809
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
None
 1.37A 4bz6C-3c10A:
39.3		 4bz6C-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 669
HIS A 670
HIS A 709
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.20A 4bz6C-3c10A:
39.3		 4bz6C-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 10 HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.25A 4bz6D-3c10A:
39.5		 4bz6D-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 10 HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
PRO A 807
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 0.80A 4bz6D-3c10A:
39.5		 4bz6D-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 10 HIS A 669
HIS A 670
ASP A 707
HIS A 709
PRO A 809
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
None
 1.43A 4bz6D-3c10A:
39.5		 4bz6D-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 10 HIS A 669
HIS A 670
HIS A 709
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.21A 4bz6D-3c10A:
39.5		 4bz6D-3c10A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		4 / 6 SER A 644
ASP A 647
ARG A 570
GLU A 576
 None
 1.11A 4eysA-3c10A:
undetectable		 4eysA-3c10A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		4 / 7 MET A 783
PRO A 791
SER A 790
VAL A 835
 None
 1.33A 4kmmA-3c10A:
undetectable		 4kmmA-3c10A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 12 ASP A 626
GLY A 678
PHE A 679
HIS A 709
ASP A 707
GLY A 841
 TSN  A 301 ( 4.0A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
ZN  A 101 (-2.1A)
TSN  A 301 ( 3.9A)
 1.49A 4lxzA-3c10A:
42.2		 4lxzA-3c10A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		10 / 12 PRO A 542
ASP A 626
HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
ASP A 801
GLY A 841
 TSN  A 301 ( 4.5A)
TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.50A 4lxzA-3c10A:
42.2		 4lxzA-3c10A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 12 PRO A 542
ASP A 626
PHE A 679
HIS A 709
ASP A 801
GLY A 842
 TSN  A 301 ( 4.5A)
TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.27A 4lxzA-3c10A:
42.2		 4lxzA-3c10A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 11 PRO A 542
ASP A 626
HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
ASP A 801
GLY A 841
 TSN  A 301 ( 4.5A)
TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.50A 4lxzB-3c10A:
42.2		 4lxzB-3c10A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 11 PRO A 542
ASP A 626
PHE A 679
HIS A 709
ASP A 801
GLY A 842
 TSN  A 301 ( 4.5A)
TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.26A 4lxzB-3c10A:
42.2		 4lxzB-3c10A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		11 / 12 PRO A 542
ASP A 626
HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 ( 4.5A)
TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.49A 4lxzC-3c10A:
42.1		 4lxzC-3c10A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		7 / 12 PRO A 542
ASP A 626
PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 ( 4.5A)
TSN  A 301 ( 4.0A)
TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.20A 4lxzC-3c10A:
42.1		 4lxzC-3c10A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 ILE A 551
ALA A 851
LEU A 837
ALA A 838
LEU A 522
 None
 0.99A 4psyA-3c10A:
undetectable		 4psyA-3c10A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.47A 4qa0A-3c10A:
39.7		 4qa0A-3c10A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.24A 4qa0A-3c10A:
39.7		 4qa0A-3c10A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		8 / 11 HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.51A 4qa0B-3c10A:
39.5		 4qa0B-3c10A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 11 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.23A 4qa0B-3c10A:
39.5		 4qa0B-3c10A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.40A 4qa2A-3c10A:
39.9		 4qa2A-3c10A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.14A 4qa2A-3c10A:
39.9		 4qa2A-3c10A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.37A 4qa2B-3c10A:
39.9		 4qa2B-3c10A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 HIS A 669
HIS A 670
HIS A 709
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.20A 4qa2B-3c10A:
39.9		 4qa2B-3c10A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.12A 4qa2B-3c10A:
39.9		 4qa2B-3c10A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 LEU A 839
LEU A 837
ALA A 798
ALA A 854
VAL A 856
 None
 1.00A 4x20B-3c10A:
undetectable		 4x20B-3c10A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 5b1aA-3c10A:
undetectable		 5b1aA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.75A 5b1aN-3c10A:
undetectable		 5b1aN-3c10A:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		10 / 12 PRO A 542
HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
LEU A 810
 TSN  A 301 ( 4.5A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 (-4.2A)
 0.56A 5eeiA-3c10A:
56.9		 5eeiA-3c10A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		10 / 12 PRO A 542
HIS A 669
HIS A 670
GLY A 678
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
LEU A 810
 TSN  A 301 ( 4.5A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 ( 3.7A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 (-4.2A)
 0.56A 5eeiB-3c10A:
56.9		 5eeiB-3c10A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		6 / 12 HIS A 669
HIS A 670
ASP A 707
HIS A 709
ASP A 801
GLY A 799
 TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
ZN  A 101 ( 2.5A)
None
 1.18A 5eenA-3c10A:
56.8		 5eenA-3c10A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 PHE A 679
HIS A 709
PHE A 738
ASP A 801
GLY A 842
 TSN  A 301 (-3.9A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
None
 1.19A 5eenA-3c10A:
56.8		 5eenA-3c10A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 PRO A 542
HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
GLY A 841
 TSN  A 301 ( 4.5A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 ( 3.9A)
 0.33A 5eenA-3c10A:
56.8		 5eenA-3c10A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 PRO A 542
HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
LEU A 810
 TSN  A 301 ( 4.5A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 (-4.2A)
 0.47A 5eenB-3c10A:
56.3		 5eenB-3c10A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		8 / 12 PRO A 542
HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
 TSN  A 301 ( 4.5A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
 0.34A 5ef8A-3c10A:
56.6		 5ef8A-3c10A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		9 / 12 PRO A 542
HIS A 669
HIS A 670
PHE A 679
ASP A 707
HIS A 709
PHE A 738
ASP A 801
LEU A 810
 TSN  A 301 ( 4.5A)
TSN  A 301 (-3.9A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
ZN  A 101 (-2.1A)
ZN  A 101 (-3.1A)
TSN  A 301 ( 4.0A)
ZN  A 101 ( 2.5A)
TSN  A 301 (-4.2A)
 0.52A 5ef8B-3c10A:
56.6		 5ef8B-3c10A:
41.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 GLY A 620
CYH A 533
CYH A 535
 ZN  A 102 ( 4.8A)
ZN  A 102 (-2.4A)
ZN  A 102 (-2.3A)
 0.97A 5inzB-3c10A:
undetectable		 5inzB-3c10A:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 5iy5A-3c10A:
undetectable		 5iy5A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 5iy5N-3c10A:
undetectable		 5iy5N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 LYS A 658
GLN A 826
ASN A 829
 None
 1.06A 5l2tA-3c10A:
undetectable		 5l2tA-3c10A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 11 ALA A 653
GLY A 833
GLY A 832
ALA A 831
ASP A 792
 None
 1.02A 5lf3K-3c10A:
undetectable
5lf3L-3c10A:
undetectable		 5lf3K-3c10A:
20.75
5lf3L-3c10A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 11 ALA A 653
GLY A 833
GLY A 832
ALA A 831
ASP A 792
 None
 1.03A 5lf3Y-3c10A:
undetectable
5lf3Z-3c10A:
undetectable		 5lf3Y-3c10A:
20.75
5lf3Z-3c10A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		4 / 5 THR A 675
HIS A 585
ALA A 671
ASP A 672
 None
 1.36A 5mfxA-3c10A:
3.1		 5mfxA-3c10A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 SER A 728
ASN A 756
GLN A 720
GLY A 711
THR A 714
 K  A 201 (-2.7A)
None
None
None
None
 1.46A 5oj0A-3c10A:
undetectable		 5oj0A-3c10A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 5w97a-3c10A:
undetectable		 5w97a-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 5xdqA-3c10A:
undetectable		 5xdqA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 5xdqN-3c10A:
undetectable		 5xdqN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 5xdxA-3c10A:
undetectable		 5xdxA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.70A 5xdxN-3c10A:
undetectable		 5xdxN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 5z84A-3c10A:
undetectable		 5z84A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 5z84N-3c10A:
undetectable		 5z84N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.73A 5z85A-3c10A:
undetectable		 5z85A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 5z85N-3c10A:
undetectable		 5z85N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.67A 5z86A-3c10A:
undetectable		 5z86A-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.69A 5z86N-3c10A:
undetectable		 5z86N-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 5zcoA-3c10A:
undetectable		 5zcoA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.70A 5zcoN-3c10A:
undetectable		 5zcoN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 5zcpA-3c10A:
undetectable		 5zcpA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 5zcpN-3c10A:
undetectable		 5zcpN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.72A 5zcqA-3c10A:
undetectable		 5zcqA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.71A 5zcqN-3c10A:
undetectable		 5zcqN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		4 / 8 GLY A 713
ASP A 705
ASP A 707
HIS A 730
 None
K  A 201 (-3.2A)
ZN  A 101 (-2.1A)
None
 0.86A 6ag0A-3c10A:
undetectable		 6ag0A-3c10A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 9 VAL A 815
HIS A 814
GLY A 770
ILE A 727
ASP A 707
 None
None
None
None
ZN  A 101 (-2.1A)
 1.32A 6c2mC-3c10A:
undetectable		 6c2mC-3c10A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		5 / 12 GLY A 833
ALA A 831
ASP A 792
VAL A 704
VAL A 794
 None
 1.08A 6dh0B-3c10A:
undetectable		 6dh0B-3c10A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.69A 6hu9a-3c10A:
undetectable		 6hu9a-3c10A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.74A 6hu9m-3c10A:
undetectable		 6hu9m-3c10A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.74A 6nknA-3c10A:
undetectable		 6nknA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.74A 6nknN-3c10A:
undetectable		 6nknN-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.74A 6nmpA-3c10A:
undetectable		 6nmpA-3c10A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3c10 HISTONE DEACETYLASE
7A
(Homo
sapiens) 		3 / 3 HIS A 709
HIS A 670
HIS A 669
 ZN  A 101 (-3.1A)
TSN  A 301 (-3.8A)
TSN  A 301 (-3.9A)
 0.75A 6nmpN-3c10A:
undetectable		 6nmpN-3c10A:
20.65