SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c18'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 3c18 NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Exiguobacterium
sibiricum) 		4 / 8 VAL A 164
VAL A 175
LEU A 165
HIS A 158
 None
 0.79A 2ddwA-3c18A:
undetectable		 2ddwA-3c18A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 3c18 NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Exiguobacterium
sibiricum) 		3 / 3 GLU A 201
PHE A 140
GLN A 202
 None
 1.03A 3r55A-3c18A:
undetectable		 3r55A-3c18A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 3c18 NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Exiguobacterium
sibiricum) 		4 / 7 ASP A 101
ASP A 105
GLU A  98
ARG A 111
 None
 1.25A 3s3oA-3c18A:
undetectable		 3s3oA-3c18A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3c18 NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Exiguobacterium
sibiricum) 		5 / 11 ALA A  14
ALA A  13
THR A  18
VAL A  43
LEU A  41
 None
 1.15A 4jbtB-3c18A:
undetectable		 4jbtB-3c18A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3c18 NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Exiguobacterium
sibiricum) 		3 / 3 PHE A 133
ASP A 135
LEU A 124
 None
 0.74A 5uhcC-3c18A:
undetectable		 5uhcC-3c18A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 3c18 NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Exiguobacterium
sibiricum) 		4 / 4 ILE A 204
LEU A 211
HIS A 153
ALA A 155
 None
 0.94A 6ck2C-3c18A:
undetectable
6ck2D-3c18A:
undetectable		 6ck2C-3c18A:
7.86
6ck2D-3c18A:
7.51