SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		4 / 8 ALA A  43
LEU A  17
ALA A  28
THR A  82
 None
 0.81A 1ie4B-3c19A:
undetectable
1ie4D-3c19A:
undetectable		 1ie4B-3c19A:
22.04
1ie4D-3c19A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		5 / 9 THR A 145
LEU A 168
VAL A 166
VAL A 116
VAL A 105
 None
 1.28A 2l8mA-3c19A:
undetectable		 2l8mA-3c19A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		4 / 7 GLY A  63
GLY A  64
VAL A  74
ARG A  89
 None
 0.65A 2oa1B-3c19A:
5.2		 2oa1B-3c19A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		4 / 6 LEU A 168
TYR A 109
ILE A 141
ILE A 147
 None
 0.87A 2q8hA-3c19A:
undetectable		 2q8hA-3c19A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		3 / 3 ARG A  52
LYS A  49
LYS A  50
 None
 1.41A 4k50E-3c19A:
undetectable		 4k50E-3c19A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		4 / 6 HIS A  42
CYH A  41
HIS A  55
LEU A  57
 PO4  A 185 (-4.2A)
None
None
None
 1.33A 5hrqD-3c19A:
undetectable
5hrqG-3c19A:
undetectable
5hrqH-3c19A:
undetectable		 5hrqD-3c19A:
12.69
5hrqG-3c19A:
5.81
5hrqH-3c19A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		4 / 6 HIS A  42
CYH A  41
HIS A  55
LEU A  57
 PO4  A 185 (-4.2A)
None
None
None
 1.31A 5hrqH-3c19A:
undetectable
5hrqK-3c19A:
undetectable
5hrqL-3c19A:
undetectable		 5hrqH-3c19A:
12.69
5hrqK-3c19A:
5.81
5hrqL-3c19A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3c19 UNCHARACTERIZED
PROTEIN MK0293
(Methanopyrus
kandleri) 		4 / 7 HIS A  42
HIS A  55
LEU A  17
VAL A  44
 PO4  A 185 (-4.2A)
None
None
PO4  A 185 ( 4.5A)
 1.06A 5m8rA-3c19A:
undetectable		 5m8rA-3c19A:
15.81