SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c1a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		6 / 12 ALA A 113
ALA A 112
ALA A 117
ILE A  74
HIS A  81
LEU A 101
 None
 1.29A 1fm6U-3c1aA:
undetectable		 1fm6U-3c1aA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 12 GLY A 237
PHE A 236
LEU A 137
ILE A 147
LEU A 182
 None
 0.95A 1lhuA-3c1aA:
undetectable		 1lhuA-3c1aA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ASP A 245
ALA A 248
ASP A 250
GLY A 266
ALA A 234
 None
 0.91A 1rl8A-3c1aA:
undetectable		 1rl8A-3c1aA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ASP A 245
ALA A 248
ASP A 250
GLY A 266
ALA A 234
 None
 0.91A 1sguB-3c1aA:
undetectable		 1sguB-3c1aA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ASP A 245
ALA A 248
ASP A 250
GLY A 266
ALA A 234
 None
 0.90A 2b7zA-3c1aA:
undetectable		 2b7zA-3c1aA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 10 ASP A 245
ALA A 248
ASP A 250
GLY A 266
ALA A 234
 None
 0.89A 3ekpB-3c1aA:
undetectable		 3ekpB-3c1aA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 10 ASP A 245
ALA A 248
ASP A 250
GLY A 266
ALA A 234
 None
 0.93A 3ekpC-3c1aA:
undetectable		 3ekpC-3c1aA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 9 ASP A 245
ALA A 248
ASP A 250
GLY A 266
ALA A 234
 None
 0.92A 3ektB-3c1aA:
undetectable		 3ektB-3c1aA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		3 / 3 PRO A 293
PHE A 286
ALA A  94
 None
 0.68A 3itaD-3c1aA:
undetectable		 3itaD-3c1aA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ALA A 113
ALA A 112
ALA A 117
ILE A  74
LEU A 101
 None
 1.27A 3uvvB-3c1aA:
undetectable		 3uvvB-3c1aA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		4 / 4 ALA A 110
ALA A 113
ALA A 114
ALA A 117
 None
 0.13A 4oaeA-3c1aA:
undetectable		 4oaeA-3c1aA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		3 / 3 TRP A 263
GLU A 153
ASP A 245
 None
 0.95A 5gqbA-3c1aA:
undetectable		 5gqbA-3c1aA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 12 GLY A 261
GLN A 258
TRP A 263
MET A 183
LEU A 233
 None
None
None
None
PG4  A 315 ( 4.2A)
 1.44A 5uc3A-3c1aA:
undetectable		 5uc3A-3c1aA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		6 / 12 ALA A 113
ALA A 112
ALA A 117
ILE A  74
HIS A  81
LEU A 101
 None
 1.28A 6a5zL-3c1aA:
undetectable		 6a5zL-3c1aA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		6 / 12 ALA A 113
ALA A 112
ALA A 117
ILE A  74
HIS A  81
LEU A 101
 None
 1.28A 6a60D-3c1aA:
undetectable		 6a60D-3c1aA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3c1a PUTATIVE
OXIDOREDUCTASE
(Magnetospirillum
magnetotacticum) 		5 / 12 GLU A 125
TYR A  24
HIS A 126
VAL A 306
GLY A 172
 None
 1.42A 6gngA-3c1aA:
3.9		 6gngA-3c1aA:
20.83