SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
3c1d REGULATORY PROTEIN
RECX

(Escherichia
coli)
3 / 3 PRO A 134
LEU A 133
GLN A 144
None
0.58A 4pevB-3c1dA:
undetectable
4pevB-3c1dA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
3c1d REGULATORY PROTEIN
RECX

(Escherichia
coli)
4 / 6 SER A 102
GLU A 104
ASP A  26
ARG A  77
None
0.84A 5cdnC-3c1dA:
undetectable
5cdnD-3c1dA:
undetectable
5cdnC-3c1dA:
16.11
5cdnD-3c1dA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
3c1d REGULATORY PROTEIN
RECX

(Escherichia
coli)
4 / 6 SER A 102
GLU A 104
ASP A  26
ARG A  77
None
0.78A 5cdnT-3c1dA:
undetectable
5cdnU-3c1dA:
undetectable
5cdnT-3c1dA:
16.11
5cdnU-3c1dA:
20.00