SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 8 ALA A 147
ASP A 156
ILE A 157
ILE A  72
 None
 0.93A 1rg9A-3c1lA:
undetectable		 1rg9A-3c1lA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		3 / 3 ARG A 111
THR A 130
VAL A 127
 None
 0.81A 2q64A-3c1lA:
undetectable		 2q64A-3c1lA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		3 / 3 ARG A 111
THR A 130
VAL A 127
 None
 1.01A 2qakA-3c1lA:
undetectable		 2qakA-3c1lA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 8 GLU A 138
ARG A 145
ARG A 141
ASP A 151
 None
 0.95A 3mjrD-3c1lA:
undetectable		 3mjrD-3c1lA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		3 / 3 PHE A 164
CYH A  85
HIS A  89
 None
PEG  A 188 ( 3.9A)
PEG  A 188 (-4.4A)
 1.20A 3u9fG-3c1lA:
undetectable		 3u9fG-3c1lA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		3 / 3 PHE A 164
CYH A  85
HIS A  89
 None
PEG  A 188 ( 3.9A)
PEG  A 188 (-4.4A)
 1.14A 3u9fS-3c1lA:
undetectable		 3u9fS-3c1lA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFX_A_ACTA404_0
(THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 5 SER A   6
LYS A   4
LEU A   8
ASP A   9
 None
 1.38A 4ifxA-3c1lA:
undetectable		 4ifxA-3c1lA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG1_A_ACTA504_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 5 SER A   6
LYS A   4
LEU A   8
ASP A   9
 None
 1.39A 4ig1A-3c1lA:
undetectable		 4ig1A-3c1lA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		3 / 3 GLU A 181
ILE A   5
ALA A  88
 None
None
PEG  A 190 ( 3.8A)
 0.66A 4wnwB-3c1lA:
undetectable		 4wnwB-3c1lA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 5 SER A   6
LYS A   4
LEU A   8
ASP A   9
 None
 1.36A 4xdtA-3c1lA:
undetectable		 4xdtA-3c1lA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 8 ALA A 147
ASP A 156
ILE A 157
ILE A  72
 None
 0.95A 5t8sA-3c1lA:
undetectable		 5t8sA-3c1lA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 7 ARG A 145
PHE A 149
ASP A 156
LEU A  64
 None
 1.03A 5uxcA-3c1lA:
undetectable		 5uxcA-3c1lA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105
(Mesorhizobium
japonicum) 		4 / 7 HIS A  89
LEU A  37
TYR A 182
VAL A  36
 PEG  A 188 (-4.4A)
PEG  A 190 ( 4.9A)
None
PEG  A 188 ( 4.5A)
 1.04A 6g2pA-3c1lA:
undetectable		 6g2pA-3c1lA:
18.96