SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		4 / 8 ALA A  39
GLY A  23
ILE A  26
ILE A  55
 None
 0.63A 1d4yB-3c24A:
undetectable		 1d4yB-3c24A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		4 / 7 THR A 116
GLY A 164
HIS A 160
ILE A 167
 None
 0.88A 1gtnF-3c24A:
undetectable
1gtnG-3c24A:
undetectable		 1gtnF-3c24A:
12.98
1gtnG-3c24A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		4 / 7 THR A 116
GLY A 164
HIS A 160
ILE A 167
 None
 0.88A 1gtnJ-3c24A:
undetectable
1gtnK-3c24A:
undetectable		 1gtnJ-3c24A:
12.98
1gtnK-3c24A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 10 ALA A  39
GLY A  20
GLY A  23
ILE A  26
ILE A  55
 None
 0.90A 1sdvA-3c24A:
undetectable		 1sdvA-3c24A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 10 GLY A 164
ALA A 165
ILE A 149
GLY A 120
ILE A 119
 None
 1.00A 1t7iA-3c24A:
undetectable		 1t7iA-3c24A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 GLY A  17
GLY A  19
LEU A  74
PRO A  75
ILE A  78
 None
 0.77A 1zq9B-3c24A:
4.7		 1zq9B-3c24A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		4 / 4 GLN A 147
GLU A 169
ILE A 149
PRO A 122
 None
 1.36A 2fcnA-3c24A:
undetectable		 2fcnA-3c24A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 ALA A  39
GLY A  20
GLY A  23
ILE A  26
ILE A  55
 None
 0.84A 2fxeA-3c24A:
undetectable		 2fxeA-3c24A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 9 VAL A  70
THR A  94
ASP A  65
ILE A  64
VAL A  90
 None
GOL  A 288 (-3.2A)
None
None
None
 1.50A 2l8mA-3c24A:
undetectable		 2l8mA-3c24A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		4 / 7 ALA A  38
TRP A  63
ILE A  40
ILE A  15
 None
 1.19A 2zm7A-3c24A:
undetectable		 2zm7A-3c24A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		4 / 7 GLY A  17
GLY A  19
GLU A  41
ALA A  73
 None
 0.74A 3fpjB-3c24A:
5.5		 3fpjB-3c24A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 GLY A 229
ALA A 222
ALA A 223
CYH A 212
ASP A 219
 None
 1.05A 3keeA-3c24A:
undetectable		 3keeA-3c24A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 11 ILE A 115
PRO A  88
ILE A  86
VAL A  96
VAL A  70
 None
 1.27A 3rf4A-3c24A:
undetectable
3rf4B-3c24A:
undetectable		 3rf4A-3c24A:
18.53
3rf4B-3c24A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 VAL A  71
GLY A 107
ALA A 103
ALA A 101
ALA A 187
 None
 1.04A 3sudD-3c24A:
undetectable		 3sudD-3c24A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 VAL A  82
PRO A 110
PRO A 104
ILE A 282
ILE A 119
 None
 1.43A 4eb6B-3c24A:
undetectable
4eb6C-3c24A:
3.3		 4eb6B-3c24A:
20.95
4eb6C-3c24A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 GLY A  17
GLY A  20
ILE A  26
LEU A  74
PRO A  75
 None
 0.93A 4gc9A-3c24A:
undetectable		 4gc9A-3c24A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 VAL A 202
ILE A 228
LEU A 231
ALA A 208
LEU A 224
 None
 1.25A 4m11C-3c24A:
undetectable		 4m11C-3c24A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 GLY A  17
ALA A  18
GLY A  20
GLY A  19
LEU A  50
 None
 0.93A 4o33A-3c24A:
2.9		 4o33A-3c24A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		4 / 4 VAL A  71
ALA A  18
ILE A  30
THR A  27
 None
 0.93A 5e4dB-3c24A:
undetectable		 5e4dB-3c24A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 ILE A 163
GLY A  93
ILE A 115
ILE A  15
LEU A  99
 None
GOL  A 288 ( 4.0A)
None
None
None
 0.90A 5e72A-3c24A:
5.2		 5e72A-3c24A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 MET A 171
THR A 170
GLY A 120
ILE A  98
ALA A 101
 None
 1.22A 5kvaA-3c24A:
4.0		 5kvaA-3c24A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 GLY A 164
ALA A 165
ILE A 149
GLY A 120
ILE A 119
 None
 0.89A 6dj1B-3c24A:
undetectable		 6dj1B-3c24A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 3c24 PUTATIVE
OXIDOREDUCTASE
(Jannaschia
sp.
CCS1) 		5 / 12 GLY A 164
ALA A 165
ILE A 149
GLY A 120
ILE A 119
 None
 0.89A 6dj2B-3c24A:
undetectable		 6dj2B-3c24A:
14.72