SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 7 VAL A  63
ARG A  90
ILE A  52
GLY A  10
 None
NO3  A 266 (-3.9A)
None
None
 0.97A 11gsA-3c26A:
undetectable		 11gsA-3c26A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 9 ASP A  45
GLY A  87
ILE A  74
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
EDO  A 269 (-3.4A)
None
None
None
 1.04A 1hxwA-3c26A:
undetectable		 1hxwA-3c26A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 7 PHE A 217
ASN A 219
TYR A 145
VAL A 260
 None
 1.40A 1wu8A-3c26A:
undetectable
1wu8C-3c26A:
undetectable		 1wu8A-3c26A:
23.25
1wu8C-3c26A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 8 VAL A  63
ARG A  90
ILE A  52
GLY A  10
 None
NO3  A 266 (-3.9A)
None
None
 0.95A 2gssA-3c26A:
undetectable		 2gssA-3c26A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 8 VAL A  63
ARG A  90
ILE A  52
GLY A  10
 None
NO3  A 266 (-3.9A)
None
None
 0.95A 2gssB-3c26A:
undetectable		 2gssB-3c26A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ASP A  45
VAL A  51
GLY A  87
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
None
EDO  A 269 (-3.4A)
None
None
 0.92A 2pynA-3c26A:
undetectable		 2pynA-3c26A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ASP A  45
VAL A  51
GLY A  87
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
None
EDO  A 269 (-3.4A)
None
None
 0.86A 2qhcB-3c26A:
undetectable		 2qhcB-3c26A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		6 / 12 ASP A  45
VAL A  51
GLY A  87
ILE A  74
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
None
EDO  A 269 (-3.4A)
None
None
None
 1.07A 2z54B-3c26A:
undetectable		 2z54B-3c26A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		6 / 12 ASP A  45
VAL A  51
GLY A  87
ILE A  74
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
None
EDO  A 269 (-3.4A)
None
None
None
 1.08A 3jw2A-3c26A:
undetectable		 3jw2A-3c26A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 4 GLY A 201
TYR A 167
GLY A 169
ASP A 220
 None
 1.22A 3kl3A-3c26A:
undetectable		 3kl3A-3c26A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ASP A  45
GLY A  87
ILE A  74
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
EDO  A 269 (-3.4A)
None
None
None
 0.94A 3lzsA-3c26A:
undetectable		 3lzsA-3c26A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ASP A  45
VAL A  51
GLY A  87
ILE A  74
VAL A  56
 NO3  A 266 (-3.1A)
None
EDO  A 269 (-3.4A)
None
None
 0.97A 3lzsA-3c26A:
undetectable		 3lzsA-3c26A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ASP A  45
VAL A  51
GLY A  87
ILE A  74
VAL A  56
 NO3  A 266 (-3.1A)
None
EDO  A 269 (-3.4A)
None
None
 0.97A 3lzsB-3c26A:
undetectable		 3lzsB-3c26A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 9 ASP A  45
GLY A  87
ILE A  74
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
EDO  A 269 (-3.4A)
None
None
None
 1.10A 3ndwB-3c26A:
undetectable		 3ndwB-3c26A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 11 ASP A  45
GLY A  87
ILE A  74
VAL A  56
ILE A  52
 NO3  A 266 (-3.1A)
EDO  A 269 (-3.4A)
None
None
None
 0.95A 4hlaB-3c26A:
undetectable		 4hlaB-3c26A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 6 PHE A 217
TYR A 145
LEU A 258
THR A  43
 None
 1.25A 4paeA-3c26A:
undetectable		 4paeA-3c26A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 6 PHE A 217
ARG A 243
PHE A 175
TYR A 180
 None
 1.09A 4uciA-3c26A:
undetectable		 4uciA-3c26A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 7 PHE A 217
ARG A 243
PHE A 175
TYR A 180
 None
 1.10A 4uciB-3c26A:
undetectable		 4uciB-3c26A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		3 / 3 TRP A  55
GLU A  77
ASP A 177
 EDO  A 269 (-4.9A)
EDO  A 269 ( 4.8A)
None
 1.04A 5gqbA-3c26A:
undetectable		 5gqbA-3c26A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		4 / 8 TRP A  55
GLU A  77
TYR A 193
ASP A 177
 EDO  A 269 (-4.9A)
EDO  A 269 ( 4.8A)
None
None
 1.06A 5gqbA-3c26A:
undetectable		 5gqbA-3c26A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ILE A 238
VAL A 242
TYR A 210
ILE A 209
MET A 234
 None
 1.10A 5n0tA-3c26A:
undetectable		 5n0tA-3c26A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ILE A 238
VAL A 242
TYR A 210
ILE A 209
MET A 234
 None
 1.06A 5n0wB-3c26A:
undetectable		 5n0wB-3c26A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ILE A 238
VAL A 242
TYR A 210
ILE A 209
MET A 234
 None
 1.04A 5n0xA-3c26A:
undetectable		 5n0xA-3c26A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821
(Thermoplasma
acidophilum) 		5 / 12 ILE A 238
VAL A 242
TYR A 210
ILE A 209
MET A 234
 None
 1.04A 5n4iA-3c26A:
undetectable		 5n4iA-3c26A:
21.12