SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
4 / 5 ASP A 104
VAL A 103
SER A 102
ASP A 127
None
1.38A 1n2xB-3c30A:
undetectable
1n2xB-3c30A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
5 / 12 ILE A 167
LEU A 143
ASN A 141
VAL A 165
ILE A 123
None
1.22A 2vn0A-3c30A:
undetectable
2vn0A-3c30A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
4 / 8 PHE A 132
ILE A 167
VAL A 165
GLY A 134
None
0.85A 3hjoB-3c30A:
undetectable
3hjoB-3c30A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
5 / 11 ASN A 193
LEU A 155
VAL A 256
ILE A 190
PHE A  64
None
1.29A 3jw5A-3c30A:
undetectable
3jw5A-3c30A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
4 / 7 ILE A 190
LEU A 168
LEU A 254
SER A 206
None
0.88A 3r9vA-3c30A:
undetectable
3r9vB-3c30A:
undetectable
3r9vA-3c30A:
26.28
3r9vB-3c30A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
3 / 3 ASN A 110
ALA A  70
ARG A  67
None
0.60A 3tj7C-3c30A:
undetectable
3tj7D-3c30A:
undetectable
3tj7C-3c30A:
21.03
3tj7D-3c30A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
5 / 12 LEU A 198
LEU A 192
ASN A 195
LEU A 220
VAL A 156
None
1.34A 3zqtA-3c30A:
undetectable
3zqtA-3c30A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio
cholerae)
5 / 9 TYR A 133
GLY A 189
LEU A 143
VAL A 156
VAL A 147
None
1.47A 4mjrA-3c30A:
1.3
4mjrA-3c30A:
22.79