SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c37'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 4 ASP A 166
HIS A 106
ARG A 214
GLU A 162
 None
ZN  A 301 (-3.2A)
None
ZN  A 301 (-2.2A)
 0.83A 1lqtA-3c37A:
undetectable		 1lqtA-3c37A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1426_0
(FPRA)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 4 ASP A 166
HIS A 106
ARG A 214
GLU A 162
 None
ZN  A 301 (-3.2A)
None
ZN  A 301 (-2.2A)
 0.59A 1lquA-3c37A:
0.0		 1lquA-3c37A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 5 PHE A  26
LEU A 128
PHE A 149
MET A 155
 None
 1.27A 1wrlC-3c37A:
undetectable		 1wrlC-3c37A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 5 ALA A 113
ALA A 165
TYR A 161
GLN A 122
 None
ZN  A 301 ( 4.6A)
None
None
 1.02A 1xl6A-3c37A:
undetectable
1xl6B-3c37A:
undetectable		 1xl6A-3c37A:
21.91
1xl6B-3c37A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		5 / 12 ALA A  78
HIS A 208
GLU A 107
HIS A 106
GLU A 162
 None
ZN  A 301 (-3.1A)
None
ZN  A 301 (-3.2A)
ZN  A 301 (-2.2A)
 1.20A 2c6nA-3c37A:
undetectable		 2c6nA-3c37A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 8 LEU A 210
ARG A 217
VAL A 170
GLY A 169
 None
 0.85A 2po5A-3c37A:
undetectable		 2po5A-3c37A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 8 LEU A 210
ARG A 217
VAL A 170
GLY A 169
 None
 0.89A 2po5B-3c37A:
undetectable		 2po5B-3c37A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		5 / 9 ALA A  94
ASP A  95
GLY A 182
LEU A 183
VAL A  49
 None
 1.07A 3em4B-3c37A:
undetectable		 3em4B-3c37A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IT4_C_BEZC503_0
(ARGININE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
ARGJ ALPHA CHAIN)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 4 ARG A 118
GLN A 164
LEU A 168
HIS A 115
 None
 1.49A 3it4C-3c37A:
0.6		 3it4C-3c37A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		5 / 10 VAL A  46
GLY A  50
VAL A  69
GLN A  34
ILE A 108
 None
 1.31A 3km6A-3c37A:
undetectable		 3km6A-3c37A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		5 / 11 VAL A 129
GLY A  81
GLY A  82
TYR A  64
ILE A  79
 None
 1.36A 3owxA-3c37A:
undetectable
3owxB-3c37A:
undetectable		 3owxA-3c37A:
24.01
3owxB-3c37A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		3 / 3 GLY A 182
THR A  98
ASN A 179
 None
 0.53A 3v4tD-3c37A:
undetectable		 3v4tD-3c37A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 6 TYR A 157
GLN A 119
GLN A 164
GLU A  61
 None
 1.44A 4azvA-3c37A:
undetectable		 4azvA-3c37A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 6 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.11A 4mi4A-3c37A:
undetectable		 4mi4A-3c37A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 7 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.12A 4mi4B-3c37A:
undetectable
4mi4C-3c37A:
undetectable		 4mi4B-3c37A:
19.69
4mi4C-3c37A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 7 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.10A 4mi4A-3c37A:
undetectable
4mi4C-3c37A:
undetectable		 4mi4A-3c37A:
19.69
4mi4C-3c37A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 8 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.11A 4mj8A-3c37A:
undetectable
4mj8C-3c37A:
undetectable		 4mj8A-3c37A:
17.86
4mj8C-3c37A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 8 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.11A 4mj8B-3c37A:
undetectable
4mj8C-3c37A:
undetectable		 4mj8B-3c37A:
17.86
4mj8C-3c37A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 7 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.08A 4mj8C-3c37A:
undetectable		 4mj8C-3c37A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 7 ARG A  83
ILE A 108
PHE A  66
LEU A  54
 None
 0.97A 4mmcA-3c37A:
undetectable		 4mmcA-3c37A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 8 TYR A 157
PHE A 149
GLY A  81
ILE A  16
 None
 0.93A 4qoiA-3c37A:
undetectable
4qoiB-3c37A:
undetectable		 4qoiA-3c37A:
24.01
4qoiB-3c37A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 7 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.03A 4r87I-3c37A:
undetectable		 4r87I-3c37A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		4 / 7 PHE A 149
ARG A 118
MET A 120
THR A 121
 None
 0.89A 5b1bN-3c37A:
undetectable
5b1bW-3c37A:
undetectable		 5b1bN-3c37A:
19.53
5b1bW-3c37A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		3 / 3 ASP A  63
VAL A  60
LEU A  54
 None
 0.68A 5e5jB-3c37A:
undetectable		 5e5jB-3c37A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3c37 PEPTIDASE, M48
FAMILY
(Geobacter
sulfurreducens) 		3 / 3 HIS A 106
ASN A 109
ALA A 113
 ZN  A 301 (-3.2A)
None
None
 0.67A 5n4tB-3c37A:
undetectable		 5n4tB-3c37A:
22.54