SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		3 / 3 SER A 292
GLU A 293
GLU A 294
 None
 0.64A 1eqbD-3c3vA:
undetectable		 1eqbD-3c3vA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		3 / 3 SER A 292
GLU A 293
GLU A 294
 None
 0.66A 1eqbB-3c3vA:
undetectable		 1eqbB-3c3vA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_A_PE2A1_1
(THYMIDINE KINASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 HIS A 202
GLU A 294
ILE A  46
ILE A  53
ARG A  81
 None
 1.17A 1ki3A-3c3vA:
undetectable		 1ki3A-3c3vA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_B_PE2B2_1
(THYMIDINE KINASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 HIS A 202
GLU A 294
ILE A  46
ILE A  53
ARG A  81
 None
 1.18A 1ki3B-3c3vA:
0.0		 1ki3B-3c3vA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		4 / 6 GLU A 114
LEU A 308
LEU A 305
GLY A 304
 None
 0.91A 1n13H-3c3vA:
undetectable
1n13K-3c3vA:
undetectable		 1n13H-3c3vA:
11.02
1n13K-3c3vA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		3 / 3 GLY A 200
GLU A 291
ASN A 197
 None
 0.69A 1zq9A-3c3vA:
undetectable		 1zq9A-3c3vA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_A_AC2A1_1
(PROTEIN (THYMIDINE
KINASE))		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 HIS A 202
GLU A 294
ILE A  46
ILE A  53
ARG A  81
 None
 1.26A 2ki5A-3c3vA:
undetectable		 2ki5A-3c3vA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_B_AC2B2_1
(PROTEIN (THYMIDINE
KINASE))		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 HIS A 202
GLU A 294
ILE A  46
ILE A  53
ARG A  81
 None
 1.29A 2ki5B-3c3vA:
0.0		 2ki5B-3c3vA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		4 / 6 ARG A 194
THR A 182
ALA A  88
PRO A  58
 None
 1.14A 2ql8A-3c3vA:
undetectable
2ql8B-3c3vA:
undetectable		 2ql8A-3c3vA:
14.01
2ql8B-3c3vA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 11 SER A 178
ILE A  92
PHE A 150
GLU A  54
LEU A  75
 None
 1.33A 2v0mA-3c3vA:
undetectable		 2v0mA-3c3vA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 11 SER A 178
ILE A  92
PHE A 150
GLU A  54
LEU A  75
 None
 1.30A 2v0mD-3c3vA:
undetectable		 2v0mD-3c3vA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 GLN A  95
SER A 415
ILE A 416
LEU A  70
TYR A 437
 None
 1.09A 3ia4A-3c3vA:
undetectable		 3ia4A-3c3vA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 GLN A  95
SER A 415
ILE A 416
LEU A  70
TYR A 437
 None
 1.10A 3ia4C-3c3vA:
undetectable		 3ia4C-3c3vA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		4 / 8 GLU A 381
PHE A  23
ARG A 474
ASP A 472
 None
 1.07A 3mjrD-3c3vA:
undetectable		 3mjrD-3c3vA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		4 / 8 ILE A  92
LEU A 166
PHE A 150
GLY A  97
 None
 1.04A 3selX-3c3vA:
undetectable		 3selX-3c3vA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		3 / 3 ASN A 197
ALA A 297
ARG A  81
 None
 0.74A 3tj7C-3c3vA:
undetectable
3tj7D-3c3vA:
undetectable		 3tj7C-3c3vA:
17.39
3tj7D-3c3vA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		4 / 6 HIS A 445
GLY A 444
ALA A 419
GLU A 440
 None
 0.92A 4ae1A-3c3vA:
2.9		 4ae1A-3c3vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 LEU A 480
ASN A 479
GLY A 482
ILE A 477
PHE A 517
 None
 1.44A 4p6xA-3c3vA:
undetectable		 4p6xA-3c3vA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 LEU A 480
ASN A 479
GLY A 482
ILE A 477
PHE A 517
 None
 1.47A 4p6xE-3c3vA:
undetectable		 4p6xE-3c3vA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		5 / 12 LEU A 480
ASN A 479
GLY A 482
ILE A 477
PHE A 517
 None
 1.47A 4p6xI-3c3vA:
undetectable		 4p6xI-3c3vA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		3 / 3 TRP A 389
ILE A  21
SER A 473
 None
 0.71A 5gqbA-3c3vA:
undetectable		 5gqbA-3c3vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		4 / 7 ILE A  21
VAL A 467
ASN A 184
PHE A 469
 None
 0.99A 5hieC-3c3vA:
0.8		 5hieC-3c3vA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3c3v ARACHIN ARAH3
ISOFORM
(Arachis
hypogaea) 		3 / 3 ARG A  76
GLY A  50
GLU A  49
 None
 0.55A 6fgdA-3c3vA:
undetectable		 6fgdA-3c3vA:
22.18