SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		4 / 4 THR J 193
GLY J 203
ASP J 204
ALA J 183
 None
 1.16A 1sg9A-3c41J:
2.4		 1sg9A-3c41J:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		5 / 12 LEU J 151
VAL J  30
GLY J  80
LEU J  47
ILE J   2
 None
 1.11A 3ku1G-3c41J:
undetectable		 3ku1G-3c41J:
25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		4 / 7 ILE J  60
LEU J  65
PHE J  53
GLY J  56
 None
 0.94A 4hajA-3c41J:
undetectable		 4hajA-3c41J:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		5 / 10 PHE J 235
GLY J  39
VAL J 192
ILE J  33
VAL J  32
 None
ANP  J 601 (-3.2A)
None
None
None
 1.14A 4jx1B-3c41J:
undetectable		 4jx1B-3c41J:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		5 / 12 PRO J  35
GLY J  39
ILE J  20
PHE J 208
ARG J 231
 None
ANP  J 601 (-3.2A)
None
None
None
 1.13A 4kosA-3c41J:
undetectable		 4kosA-3c41J:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		5 / 12 PRO J  35
GLY J  39
ILE J  20
PHE J 208
ARG J 231
 None
ANP  J 601 (-3.2A)
None
None
None
 1.16A 4kotA-3c41J:
undetectable		 4kotA-3c41J:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		5 / 12 PRO J  35
GLY J  39
ILE J  20
PHE J 208
ARG J 231
 None
ANP  J 601 (-3.2A)
None
None
None
 1.15A 4kovA-3c41J:
undetectable		 4kovA-3c41J:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		4 / 8 LEU J 159
VAL J 190
VAL J   4
VAL J  22
 None
 0.98A 4l4bA-3c41J:
undetectable		 4l4bA-3c41J:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		4 / 8 LEU J 182
VAL J  82
VAL J 191
LEU J 151
 None
 0.99A 4puoC-3c41J:
undetectable		 4puoC-3c41J:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		5 / 7 PHE J 235
GLY J  39
VAL J 192
ILE J  33
VAL J  32
 None
ANP  J 601 (-3.2A)
None
None
None
 1.13A 5ik1A-3c41J:
undetectable		 5ik1A-3c41J:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		5 / 12 LEU J 167
VAL J 172
GLY J 173
SER J 177
VAL J  82
 None
 1.43A 6a94A-3c41J:
undetectable		 6a94A-3c41J:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3c41 AMINO ACID ABC
TRANSPORTER (ARTP)
(Geobacillus
stearothermophil
us) 		4 / 8 LEU J 159
VAL J 190
VAL J   4
VAL J  22
 None
 0.98A 6cp4A-3c41J:
undetectable		 6cp4A-3c41J:
20.49