SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c4n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 ILE A 229
LEU A 373
MET A  47
VAL A  41
 None
None
ADP  A 411 ( 4.9A)
None
 0.59A 1a29A-3c4nA:
undetectable		 1a29A-3c4nA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 5 LEU A 374
LEU A 372
LEU A 197
GLY A 236
 None
 1.01A 1a4lC-3c4nA:
undetectable		 1a4lC-3c4nA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 THR A  79
GLY A  45
GLY A 383
GLY A 375
 ADP  A 411 (-3.6A)
ADP  A 411 (-3.5A)
None
ADP  A 411 ( 4.4A)
 0.75A 1d0vA-3c4nA:
undetectable		 1d0vA-3c4nA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 ARG A 272
PRO A 171
LEU A 106
TYR A 169
ASP A  90
 None
 1.37A 1e7wA-3c4nA:
3.6		 1e7wA-3c4nA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 ALA A  50
GLY A 172
ALA A  49
THR A  79
 None
None
None
ADP  A 411 (-3.6A)
 0.74A 1gtnI-3c4nA:
undetectable
1gtnJ-3c4nA:
undetectable		 1gtnI-3c4nA:
12.17
1gtnJ-3c4nA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
VAL A  40
ILE A 223
VAL A 230
ILE A 228
 None
 1.01A 1hxbB-3c4nA:
undetectable		 1hxbB-3c4nA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 THR A  79
GLY A  45
GLY A 383
GLY A 375
 ADP  A 411 (-3.6A)
ADP  A 411 (-3.5A)
None
ADP  A 411 ( 4.4A)
 0.74A 1jhaA-3c4nA:
undetectable		 1jhaA-3c4nA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		6 / 12 ILE A  42
ALA A 232
ALA A 231
LEU A 373
LEU A 239
LEU A  66
 ADP  A 411 (-4.9A)
ADP  A 411 (-3.6A)
None
None
ADP  A 411 (-4.4A)
None
 1.37A 1k74A-3c4nA:
undetectable		 1k74A-3c4nA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 384
LEU A 390
ALA A 391
LEU A  55
VAL A  41
 None
 0.76A 1s9pB-3c4nA:
undetectable		 1s9pB-3c4nA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 384
LEU A 390
ALA A 391
LEU A  55
VAL A  41
 None
 0.75A 1s9pC-3c4nA:
undetectable		 1s9pC-3c4nA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 5 GLU A 319
THR A 311
LEU A 313
LEU A 306
 None
 1.03A 1u18B-3c4nA:
undetectable		 1u18B-3c4nA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.90A 2f80A-3c4nA:
undetectable		 2f80A-3c4nA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.87A 2f81B-3c4nA:
undetectable		 2f81B-3c4nA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.94A 2f8gA-3c4nA:
undetectable		 2f8gA-3c4nA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.81A 2f8gB-3c4nA:
undetectable		 2f8gB-3c4nA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.92A 2ienA-3c4nA:
undetectable		 2ienA-3c4nA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.80A 2o4lB-3c4nA:
undetectable		 2o4lB-3c4nA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.85A 2pynA-3c4nA:
undetectable		 2pynA-3c4nA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.84A 2pynB-3c4nA:
undetectable		 2pynB-3c4nA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.87A 2q63A-3c4nA:
undetectable		 2q63A-3c4nA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.86A 2q63B-3c4nA:
undetectable		 2q63B-3c4nA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.82A 2qakB-3c4nA:
undetectable		 2qakB-3c4nA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 GLY A 375
ILE A 229
ALA A 351
HIS A 250
 ADP  A 411 ( 4.4A)
None
None
None
 0.89A 2x0pA-3c4nA:
undetectable		 2x0pA-3c4nA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 5 VAL A 288
GLN A 281
ARG A 255
ARG A 170
 None
 1.39A 3bjwE-3c4nA:
0.7		 3bjwE-3c4nA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 6 VAL A 288
GLN A 281
ARG A 255
ARG A 170
 None
 1.16A 3bjwF-3c4nA:
0.5		 3bjwF-3c4nA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.86A 3bvbA-3c4nA:
undetectable		 3bvbA-3c4nA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.89A 3bvbB-3c4nA:
undetectable		 3bvbB-3c4nA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.83A 3cywB-3c4nA:
undetectable		 3cywB-3c4nA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 VAL A 198
ILE A  42
VAL A  40
GLY A 201
 None
ADP  A 411 (-4.9A)
None
None
 0.81A 3hjoB-3c4nA:
undetectable		 3hjoB-3c4nA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.85A 3jvyA-3c4nA:
undetectable		 3jvyA-3c4nA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.85A 3jw2A-3c4nA:
undetectable		 3jw2A-3c4nA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.82A 3jw2B-3c4nA:
undetectable		 3jw2B-3c4nA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.87A 3lzsA-3c4nA:
undetectable		 3lzsA-3c4nA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.87A 3lzsB-3c4nA:
undetectable		 3lzsB-3c4nA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.84A 3lzuA-3c4nA:
undetectable		 3lzuA-3c4nA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.84A 3lzuB-3c4nA:
undetectable		 3lzuB-3c4nA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
VAL A  40
ILE A 223
VAL A 230
ILE A 228
 None
 0.98A 3mwsB-3c4nA:
undetectable		 3mwsB-3c4nA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 ALA A 385
GLY A 383
TRP A  86
MET A  47
ALA A  99
 None
None
None
ADP  A 411 ( 4.9A)
None
 1.17A 3ou7B-3c4nA:
3.2		 3ou7B-3c4nA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		3 / 3 TYR A  54
LEU A 190
ARG A  56
 None
 0.81A 3sufB-3c4nA:
undetectable		 3sufB-3c4nA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.82A 3tkwA-3c4nA:
undetectable		 3tkwA-3c4nA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.81A 3tkwB-3c4nA:
undetectable		 3tkwB-3c4nA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.83A 3tl9B-3c4nA:
undetectable		 3tl9B-3c4nA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 7 THR A 168
ALA A 166
THR A  87
VAL A  85
 None
 0.79A 4ik7A-3c4nA:
undetectable		 4ik7A-3c4nA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 THR A 168
ALA A 166
THR A  87
VAL A  85
 None
 0.73A 4ik7B-3c4nA:
undetectable		 4ik7B-3c4nA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.82A 4jecA-3c4nA:
undetectable		 4jecA-3c4nA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 ALA A 148
PRO A 146
LEU A 152
LEU A 271
 None
 0.96A 4jjkA-3c4nA:
2.2		 4jjkA-3c4nA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 189
ALA A 179
ASN A 192
GLY A  71
ALA A 231
 None
 0.96A 4nkxB-3c4nA:
undetectable		 4nkxB-3c4nA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 189
ALA A 179
ASN A 192
GLY A  71
ALA A 231
 None
 0.84A 4nkxD-3c4nA:
undetectable		 4nkxD-3c4nA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 6 LEU A 151
LEU A 276
LEU A 324
LEU A 336
 None
 0.99A 5gs4A-3c4nA:
undetectable		 5gs4A-3c4nA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 ILE A 229
VAL A  41
GLU A  68
ASN A  74
ALA A 178
 None
None
ADP  A 411 (-2.3A)
ADP  A 411 (-3.8A)
None
 1.04A 5lg3E-3c4nA:
undetectable		 5lg3E-3c4nA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 GLY A 236
LEU A 372
GLN A 242
VAL A 240
LEU A 366
 None
 0.97A 5ubbA-3c4nA:
undetectable		 5ubbA-3c4nA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 ALA A  44
GLY A  71
GLY A 236
LEU A 197
LEU A 239
 None
None
None
None
ADP  A 411 (-4.4A)
 1.03A 5wwsA-3c4nA:
2.5		 5wwsA-3c4nA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 7 LEU A 336
ARG A 279
THR A 277
LEU A 276
 None
 0.97A 5zcpA-3c4nA:
undetectable
5zcpJ-3c4nA:
undetectable		 5zcpA-3c4nA:
22.63
5zcpJ-3c4nA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 TYR A 285
ALA A 330
ALA A 150
LEU A 142
LEU A 126
 None
 1.16A 6aybA-3c4nA:
undetectable		 6aybA-3c4nA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 9 ASP A  90
LEU A 271
VAL A 162
ASP A 163
 None
 0.94A 6c2mD-3c4nA:
undetectable		 6c2mD-3c4nA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		4 / 8 LEU A 317
LEU A 318
LEU A 260
GLY A 335
 None
 0.82A 6ce2A-3c4nA:
0.7		 6ce2A-3c4nA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3c4n UNCHARACTERIZED
PROTEIN DR_0571
(Deinococcus
radiodurans) 		5 / 12 LEU A 370
GLY A 200
VAL A  40
VAL A 230
ILE A 228
 None
 0.92A 6dh6A-3c4nA:
undetectable		 6dh6A-3c4nA:
11.92