SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.18A 1cilA-3c4qA:
undetectable		 1cilA-3c4qA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 ALA A  87
PHE A  88
GLY A  90
LEU A  81
PRO A  72
 None
 0.93A 1cmcA-3c4qA:
undetectable
1cmcB-3c4qA:
undetectable		 1cmcA-3c4qA:
13.37
1cmcB-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.28A 1dmyB-3c4qA:
undetectable		 1dmyB-3c4qA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 ARG A 212
ALA A 301
GLY A 218
ALA A 305
ILE A 219
 None
 1.16A 1gtnH-3c4qA:
undetectable
1gtnI-3c4qA:
undetectable		 1gtnH-3c4qA:
11.65
1gtnI-3c4qA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ALA A  87
PHE A  88
GLY A  90
LEU A  81
PRO A  72
 None
 1.03A 1mj2A-3c4qA:
undetectable
1mj2B-3c4qA:
undetectable		 1mj2A-3c4qA:
13.37
1mj2B-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ALA A  87
PHE A  88
GLY A  90
LEU A  81
PRO A  72
 None
 1.00A 1mj2C-3c4qA:
undetectable
1mj2D-3c4qA:
undetectable		 1mj2C-3c4qA:
13.37
1mj2D-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ALA A  87
PHE A  88
GLY A  90
LEU A  81
PRO A  72
 None
 1.00A 1mjoC-3c4qA:
undetectable
1mjoD-3c4qA:
undetectable		 1mjoC-3c4qA:
13.37
1mjoD-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 LEU A  81
PRO A  72
ALA A  87
PHE A  88
GLY A  90
 None
 0.96A 1mjqA-3c4qA:
undetectable
1mjqB-3c4qA:
undetectable		 1mjqA-3c4qA:
13.37
1mjqB-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 LEU A  81
PRO A  72
ALA A  87
PHE A  88
GLY A  90
 None
 0.98A 1mjqC-3c4qA:
undetectable
1mjqD-3c4qA:
undetectable		 1mjqC-3c4qA:
13.37
1mjqD-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ALA A  87
PHE A  88
GLY A  90
LEU A  81
PRO A  72
 None
 0.94A 1mjqC-3c4qA:
undetectable
1mjqD-3c4qA:
undetectable		 1mjqC-3c4qA:
13.37
1mjqD-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 LEU A  81
PRO A  72
ALA A  87
PHE A  88
GLY A  90
 None
 0.99A 1mjqI-3c4qA:
undetectable
1mjqJ-3c4qA:
undetectable		 1mjqI-3c4qA:
13.37
1mjqJ-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ALA A  87
PHE A  88
GLY A  90
LEU A  81
PRO A  72
 None
 0.95A 1mjqI-3c4qA:
undetectable
1mjqJ-3c4qA:
undetectable		 1mjqI-3c4qA:
13.37
1mjqJ-3c4qA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 LEU A 128
ALA A 165
LEU A 161
ALA A 132
ALA A 169
 None
 1.04A 1sa1A-3c4qA:
4.1
1sa1B-3c4qA:
6.0		 1sa1A-3c4qA:
23.09
1sa1B-3c4qA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 LEU A 128
ALA A 165
LEU A 161
ALA A 132
ALA A 169
 None
 1.05A 1sa1C-3c4qA:
5.7
1sa1D-3c4qA:
6.1		 1sa1C-3c4qA:
23.09
1sa1D-3c4qA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.27A 1zgfA-3c4qA:
undetectable		 1zgfA-3c4qA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 7 ARG A 294
LEU A 299
PRO A 312
VAL A 309
 None
UDP  A 600 ( 4.3A)
None
None
 1.30A 2hrcA-3c4qA:
2.9		 2hrcA-3c4qA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 8 LEU A 232
ARG A 294
LEU A 299
PRO A 312
VAL A 309
 None
None
UDP  A 600 ( 4.3A)
None
None
 1.47A 2po5B-3c4qA:
3.4		 2po5B-3c4qA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.24A 2pouA-3c4qA:
undetectable		 2pouA-3c4qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 7 ALA A  36
GLY A  39
ASP A  43
ARG A  64
 None
 0.83A 2uyqA-3c4qA:
2.5		 2uyqA-3c4qA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.19A 3bl1A-3c4qA:
undetectable		 3bl1A-3c4qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.20A 3dcwA-3c4qA:
undetectable		 3dcwA-3c4qA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.21A 3dd0A-3c4qA:
undetectable		 3dd0A-3c4qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 GLY A 230
PRO A  16
GLY A  22
GLY A  23
ILE A 261
 UDP  A 600 ( 4.0A)
UDP  A 600 (-4.0A)
UDP  A 600 ( 3.8A)
UDP  A 600 (-3.2A)
None
 0.91A 3douA-3c4qA:
4.5		 3douA-3c4qA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 109
VAL A   3
ILE A  40
VAL A  42
THR A  31
 None
 0.91A 3fw3A-3c4qA:
undetectable		 3fw3A-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 109
VAL A   3
ILE A  40
VAL A  42
THR A  31
 None
 0.90A 3fw3B-3c4qA:
undetectable		 3fw3B-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 8 ALA A 407
ILE A 406
ASN A 408
PRO A 127
 None
 1.02A 3fxrA-3c4qA:
undetectable		 3fxrA-3c4qA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.16A 3hkuA-3c4qA:
undetectable		 3hkuA-3c4qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.18A 3hs4A-3c4qA:
undetectable		 3hs4A-3c4qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 GLU A 346
GLY A 350
THR A 349
 None
 0.59A 3iazA-3c4qA:
undetectable		 3iazA-3c4qA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 TYR A 402
GLY A  39
ALA A  36
ILE A  44
ILE A   6
 None
 1.23A 3ld6A-3c4qA:
undetectable		 3ld6A-3c4qA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 8 ILE A 342
SER A 317
GLY A 339
PRO A 195
 None
 0.91A 3lslA-3c4qA:
undetectable
3lslD-3c4qA:
1.4		 3lslA-3c4qA:
21.26
3lslD-3c4qA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 8 PRO A 195
ILE A 342
SER A 317
GLY A 339
 None
 0.84A 3lslA-3c4qA:
undetectable
3lslD-3c4qA:
undetectable		 3lslA-3c4qA:
21.26
3lslD-3c4qA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 HIS A 107
HIS A 109
MET A   5
 None
 0.90A 3mihA-3c4qA:
undetectable		 3mihA-3c4qA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.13A 3ml5A-3c4qA:
undetectable		 3ml5A-3c4qA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 GLY A 350
ILE A 333
ALA A 334
VAL A 344
GLU A 384
 None
 1.15A 3nvkI-3c4qA:
4.2		 3nvkI-3c4qA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 VAL A 344
ALA A 335
ARG A 336
VAL A 353
ILE A 333
 None
 1.39A 3retA-3c4qA:
undetectable
3retB-3c4qA:
undetectable		 3retA-3c4qA:
13.38
3retB-3c4qA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.18A 3v2jA-3c4qA:
undetectable		 3v2jA-3c4qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.14A 4coqA-3c4qA:
undetectable		 4coqA-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 9 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.16A 4coqB-3c4qA:
undetectable		 4coqB-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 7 ALA A 197
ALA A 343
ALA A 386
THR A 388
 None
 0.91A 4du2B-3c4qA:
undetectable		 4du2B-3c4qA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ILE A 261
ALA A 322
GLU A 316
ALA A 334
VAL A 332
 None
None
UDP  A 600 (-3.2A)
None
None
 1.09A 4hfpD-3c4qA:
undetectable		 4hfpD-3c4qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.20A 4k0sA-3c4qA:
undetectable		 4k0sA-3c4qA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 GLY A 196
GLU A  34
THR A  31
 None
 0.54A 4kouA-3c4qA:
undetectable		 4kouA-3c4qA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 GLY A 205
PRO A 204
ALA A 327
 None
 0.41A 4qn9B-3c4qA:
undetectable		 4qn9B-3c4qA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 THR A 210
ALA A 306
ALA A 227
GLY A 329
THR A 330
 MG  A 602 ( 4.7A)
MG  A 602 (-4.6A)
None
None
MG  A 602 (-2.7A)
 1.03A 4qvyK-3c4qA:
undetectable
4qvyL-3c4qA:
undetectable		 4qvyK-3c4qA:
20.05
4qvyL-3c4qA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 THR A 210
ALA A 306
ALA A 227
GLY A 329
THR A 330
 MG  A 602 ( 4.7A)
MG  A 602 (-4.6A)
None
None
MG  A 602 (-2.7A)
 1.03A 4qvyY-3c4qA:
undetectable
4qvyZ-3c4qA:
undetectable		 4qvyY-3c4qA:
20.05
4qvyZ-3c4qA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 GLY A 264
PRO A 265
GLN A 233
 None
 0.56A 4qwpB-3c4qA:
undetectable		 4qwpB-3c4qA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 5 ILE A 342
PRO A 341
HIS A 356
VAL A 321
 None
None
None
UDP  A 600 ( 3.9A)
 1.04A 4s0vA-3c4qA:
22.9		 4s0vA-3c4qA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 SER A 191
THR A  31
THR A 394
ALA A 395
TYR A 402
 None
 1.38A 4u15B-3c4qA:
undetectable		 4u15B-3c4qA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.11A 4uovA-3c4qA:
undetectable		 4uovA-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.14A 4uovB-3c4qA:
undetectable		 4uovB-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.12A 4uovC-3c4qA:
undetectable		 4uovC-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.13A 4uovD-3c4qA:
undetectable		 4uovD-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.13A 4uovE-3c4qA:
undetectable		 4uovE-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.12A 4uovF-3c4qA:
undetectable		 4uovF-3c4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.15A 4x5sB-3c4qA:
undetectable		 4x5sB-3c4qA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 6 TYR A 303
ILE A 260
VAL A 309
ALA A 227
 None
 0.92A 5cu6A-3c4qA:
undetectable		 5cu6A-3c4qA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ARG A 212
ALA A 301
GLY A 218
ALA A 305
ILE A 219
 None
 1.16A 5eeuI-3c4qA:
undetectable
5eeuJ-3c4qA:
undetectable		 5eeuI-3c4qA:
11.65
5eeuJ-3c4qA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.16A 5jn8A-3c4qA:
undetectable		 5jn8A-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.14A 5jn8B-3c4qA:
undetectable		 5jn8B-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.20A 5jn9A-3c4qA:
undetectable		 5jn9A-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.17A 5jn9B-3c4qA:
undetectable		 5jn9B-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.18A 5jn9D-3c4qA:
undetectable		 5jn9D-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.15A 5jnaB-3c4qA:
undetectable		 5jnaB-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.12A 5jnaC-3c4qA:
undetectable		 5jnaC-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.16A 5jnaD-3c4qA:
undetectable		 5jnaD-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 11 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.16A 5jncA-3c4qA:
undetectable		 5jncA-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.16A 5jncB-3c4qA:
undetectable		 5jncB-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.15A 5ku6A-3c4qA:
undetectable		 5ku6A-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 107
HIS A 109
VAL A   3
LEU A  35
THR A  31
 None
 1.14A 5ku6B-3c4qA:
undetectable		 5ku6B-3c4qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 TYR A  27
SER A 194
TRP A 391
 None
 1.03A 5n8jB-3c4qA:
undetectable		 5n8jB-3c4qA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 TYR A  27
SER A 194
TRP A 391
 None
 1.03A 5n8jA-3c4qA:
undetectable		 5n8jA-3c4qA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		3 / 3 TYR A  27
SER A 194
TRP A 391
 None
 0.99A 5n8jD-3c4qA:
undetectable		 5n8jD-3c4qA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 GLY A  23
HIS A 133
LYS A 236
GLU A 316
GLY A 319
 UDP  A 600 (-3.2A)
None
UDP  A 600 (-2.7A)
UDP  A 600 (-3.2A)
None
 0.98A 5vncC-3c4qA:
26.5		 5vncC-3c4qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 133
ASN A 171
LYS A 236
GLU A 316
GLY A 319
 None
None
UDP  A 600 (-2.7A)
UDP  A 600 (-3.2A)
None
 1.41A 5vncC-3c4qA:
26.5		 5vncC-3c4qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 6 LYS A 286
ARG A 276
GLU A 285
ALA A 279
 None
 0.95A 6an0A-3c4qA:
3.9		 6an0A-3c4qA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 TRP A 391
ASN A 171
HIS A 109
LEU A  35
THR A  31
 None
 1.22A 6bbsA-3c4qA:
undetectable		 6bbsA-3c4qA:
14.64