SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3c4r UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 TRP A  15
VAL A  23
PRO A  24
 None
 0.98A 1rg1A-3c4rA:
undetectable		 1rg1A-3c4rA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3c4r UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 TRP A  15
VAL A  23
PRO A  24
 None
 0.96A 1rh0A-3c4rA:
undetectable		 1rh0A-3c4rA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3c4r UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 8 HIS A  95
SER A  94
ARG A  93
VAL A 104
 None
 1.27A 1u1jA-3c4rA:
undetectable		 1u1jA-3c4rA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 3c4r UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 LYS A  72
PRO A  40
LYS A  57
 None
 1.49A 4dr5L-3c4rA:
undetectable		 4dr5L-3c4rA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3c4r UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 LYS A  72
PRO A  40
LYS A  57
 None
 1.46A 4duzL-3c4rA:
undetectable		 4duzL-3c4rA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3c4r UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 LYS A  72
PRO A  40
LYS A  57
 None
 1.26A 4dv7L-3c4rA:
undetectable		 4dv7L-3c4rA:
19.33