SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		3 / 3 ARG A 140
ARG A  90
ILE A 147
 None
 0.54A 1uobA-3c5oA:
undetectable		 1uobA-3c5oA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		5 / 9 PHE A  11
GLY A  48
VAL A  10
GLN A 151
GLY A  45
 None
 1.39A 3kmoA-3c5oA:
undetectable		 3kmoA-3c5oA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		5 / 7 PHE A 119
PHE A  74
THR A  76
ILE A  46
PHE A  11
 None
 1.23A 4ejjA-3c5oA:
undetectable		 4ejjA-3c5oA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		4 / 6 PHE A 119
VAL A  84
TYR A  72
ILE A  13
 None
 0.90A 5iwuA-3c5oA:
1.5		 5iwuA-3c5oA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		4 / 6 PHE A 119
VAL A  84
TYR A  72
ILE A 147
 None
 0.83A 5iwuA-3c5oA:
1.5		 5iwuA-3c5oA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		5 / 10 TYR A 126
THR A  12
THR A  76
GLY A  48
GLU A  40
 None
 1.21A 6mb7A-3c5oA:
undetectable		 6mb7A-3c5oA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		5 / 10 TYR A 126
THR A  12
THR A  76
GLY A  48
GLU A  40
 None
 1.20A 6mb9A-3c5oA:
undetectable		 6mb9A-3c5oA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		5 / 10 TYR A 126
THR A  12
THR A  76
GLY A  48
GLU A  40
 None
 1.26A 6mb9B-3c5oA:
undetectable		 6mb9B-3c5oA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		5 / 10 TYR A 126
THR A  12
THR A  76
GLY A  48
GLU A  40
 None
 1.28A 6mb9C-3c5oA:
undetectable		 6mb9C-3c5oA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 3c5o UPF0311 PROTEIN
RPA1785
(Rhodopseudomonas
palustris) 		5 / 10 TYR A 126
THR A  12
THR A  76
GLY A  48
GLU A  40
 None
 1.16A 6mb9D-3c5oA:
undetectable		 6mb9D-3c5oA:
21.29