SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NRR_B_D16B520_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3c5p	PROTEIN BAS0735 OF UNKNOWN FUNCTION (Bacillus anthracis)	5 / 12	HIS A 170 ASP A 148 LEU A 182 ILE A 13 PRO A 14	None MG A 301 ( 2.7A) None None None	0.94A	3nrrB-3c5pA: undetectable	3nrrB-3c5pA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_B_SAMB501_1 (PEPTIDE N-METHYLTRANSFERASE)	3c5p	PROTEIN BAS0735 OF UNKNOWN FUNCTION (Bacillus anthracis)	4 / 4	GLY A 89 ALA A 91 MET A 47 THR A 93	None	1.49A	5n0sB-3c5pA: undetectable	5n0sB-3c5pA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_B_ADNB401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	3c5p	PROTEIN BAS0735 OF UNKNOWN FUNCTION (Bacillus anthracis)	5 / 12	GLY A 149 ASP A 187 ASP A 128 ALA A 179 PRO A 125	None MG A 302 (-3.2A) MG A 301 (-3.3A) None None	1.10A	6bq4B-3c5pA: undetectable	6bq4B-3c5pA: 16.58